MACF1 and GOLGA4

Number of citations of the paper that reports this interaction (PMID 15265687)
10

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		MACF1	GOLGA4
Gene Name		microtubule-actin crosslinking factor 1	golgin A4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytoskeleton Microtubule Plasma Membrane Actin Cytoskeleton Ruffle Membrane	Golgi Membrane Nucleoplasm Cytoplasm Golgi Apparatus Trans-Golgi Network Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Calcium Ion Binding Protein Binding Microtubule Binding ATPase Activity Poly(A) RNA Binding Actin Filament Binding	Protein Binding GTPase Binding
	Biological Process	Mesoderm Formation Posttranslational Protein Targeting To Membrane Movement Of Cell Or Subcellular Component Cell Cycle Arrest Establishment Or Maintenance Of Cell Polarity Metabolic Process Regulation Of Epithelial Cell Migration Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Regulation Of Microtubule-based Process Wound Healing Golgi To Plasma Membrane Protein Transport Positive Regulation Of Axon Extension Regulation Of Focal Adhesion Assembly	Protein Targeting To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Protein Transport Positive Regulation Of Axon Extension
Pathways
Drugs
Diseases
GWAS		HDL cholesterol ( 20686565)
Protein-Protein Interactions		24 interactors: ACTA1 APC ATF7IP CDC5L CEP63 CNTNAP2 CNTNAP4 DISC1 DTNBP1 ESRRA EXOC1 GOLGA4 JUN MAPK9 MAPRE1 NRCAM NRXN1 NRXN2 PLXND1 PRKCD SKIL TANGO6 TNIK TRAF3IP1	8 interactors: APP ARL1 ARL3 EXOC1 MACF1 RAB6A TNIK TRAF3IP1
Entrez ID		23499	2803
HPRD ID		09750	03941
Ensembl ID		ENSG00000127603	ENSG00000144674
Uniprot IDs		Q6ZSD7 Q9UPN3	Q13439 Q49A56
PDB IDs			1R4A 1UPT
Enriched GO Terms of Interacting Partners?		Nervous System Development Generation Of Neurons Neurogenesis Regulation Of Cell Projection Organization Cell Projection Organization System Development Developmental Process Multicellular Organismal Development Vocalization Behavior Protein Localization Regulation Of Cellular Component Organization Cellular Localization Neuron Projection Development Anatomical Structure Development Membrane Organization Synapse Assembly Neuroligin Clustering Organelle Organization Response To Mechanical Stimulus Neuron Development Cellular Protein Localization Gephyrin Clustering Cell Differentiation Signaling Cellular Component Assembly Cell Communication Negative Regulation Of Filopodium Assembly Neuron Differentiation Regulation Of Cell Differentiation Social Behavior Vocal Learning Learning Positive Regulation Of Cell Differentiation Postsynaptic Membrane Assembly Regulation Of Grooming Behavior Synapse Organization Cell Development Regulation Of Neuron Projection Development Postsynaptic Density Protein 95 Clustering Anatomical Structure Formation Involved In Morphogenesis Auditory Behavior Movement Of Cell Or Subcellular Component Regulation Of Signaling Neuronal Ion Channel Clustering Regulation Of Cell Morphogenesis Neuron Cell-cell Adhesion Positive Regulation Of Cell Development Regulation Of Binding Cell Projection Morphogenesis Learning Or Memory	Cellular Localization Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Establishment Of Localization In Cell Golgi Vesicle Transport Vesicle-mediated Transport Intracellular Transport Microtubule-based Movement Protein Localization Movement Of Cell Or Subcellular Component Intraciliary Transport Microtubule-based Process Protein Localization To Golgi Apparatus Transport Retrograde Transport, Endosome To Golgi Endomembrane System Organization Cell Projection Organization Nervous System Development Post-Golgi Vesicle-mediated Transport Protein Localization To Organelle Cellular Protein Localization Regulation Of Neuron Differentiation Synaptic Growth At Neuromuscular Junction Protein Transport Establishment Of Protein Localization Small GTPase Mediated Signal Transduction Collateral Sprouting In Absence Of Injury Minus-end-directed Organelle Transport Along Microtubule Peptidyl-cysteine Methylation Generation Of Neurons Protein Localization To Plasma Membrane Regulation Of Neurogenesis Neurogenesis Collateral Sprouting Axon Midline Choice Point Recognition Organelle Organization Cilium Organization Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Intracellular Signal Transduction Endosomal Transport Signal Transduction Cell Projection Morphogenesis Axon Choice Point Recognition Regulation Of Cell Development Membrane Organization Cilium Morphogenesis Cell Part Morphogenesis Plasma Membrane Organization Posttranslational Protein Targeting To Membrane Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning
Tagcloud ?		a2 comprehensive cytoskeleton ecm focal genotypes hbv hbx hcc hepatocellular hepg2 hmgb1 lamin lc migration ms nevertheless obscure platform preliminary profile proteasome proteomics psma3 s100a11 s100a4 s100a6 supported turn
Tagcloud (Difference) ?		a2 comprehensive cytoskeleton ecm focal genotypes hbv hbx hcc hepatocellular hepg2 hmgb1 lamin lc migration ms nevertheless obscure platform preliminary profile proteasome proteomics psma3 s100a11 s100a4 s100a6 supported turn
Tagcloud (Intersection) ?