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MACF1 and EXOC1
Number of citations of the paper that reports this interaction (PMID
17043677
)
96
Data Source:
BioGRID
(two hybrid)
MACF1
EXOC1
Gene Name
microtubule-actin crosslinking factor 1
exocyst complex component 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Golgi Apparatus
Cytoskeleton
Microtubule
Plasma Membrane
Actin Cytoskeleton
Ruffle Membrane
Exocyst
Cytosol
Plasma Membrane
Membrane
Molecular Function
Actin Binding
Calcium Ion Binding
Protein Binding
Microtubule Binding
ATPase Activity
Poly(A) RNA Binding
Actin Filament Binding
Protein Binding
Biological Process
Mesoderm Formation
Posttranslational Protein Targeting To Membrane
Movement Of Cell Or Subcellular Component
Cell Cycle Arrest
Establishment Or Maintenance Of Cell Polarity
Metabolic Process
Regulation Of Epithelial Cell Migration
Wnt Signaling Pathway
Positive Regulation Of Wnt Signaling Pathway
Regulation Of Microtubule-based Process
Wound Healing
Golgi To Plasma Membrane Protein Transport
Positive Regulation Of Axon Extension
Regulation Of Focal Adhesion Assembly
Exocytosis
Organelle Organization
Protein Transport
Cellular Protein Metabolic Process
Membrane Organization
Pathways
Peptide hormone metabolism
Cargo trafficking to the periciliary membrane
Organelle biogenesis and maintenance
Translocation of GLUT4 to the plasma membrane
VxPx cargo-targeting to cilium
Assembly of the primary cilium
Insulin processing
Drugs
Diseases
GWAS
HDL cholesterol (
20686565
)
Cervical cancer (
23817570
)
Protein-Protein Interactions
24 interactors:
ACTA1
APC
ATF7IP
CDC5L
CEP63
CNTNAP2
CNTNAP4
DISC1
DTNBP1
ESRRA
EXOC1
GOLGA4
JUN
MAPK9
MAPRE1
NRCAM
NRXN1
NRXN2
PLXND1
PRKCD
SKIL
TANGO6
TNIK
TRAF3IP1
28 interactors:
ATG14
CCDC88A
CCDC93
CCSER2
CDC5L
CEP295
COLEC12
DISC1
DST
GOLGA4
KANSL1
KDM1A
KIAA0226
KIAA1551
KIF5A
LUC7L2
MACF1
NUF2
RALA
RB1CC1
SFR1
SH3BP5
SPTAN1
SRGAP2
SYBU
TRAF3IP1
TRIM9
TRIO
Entrez ID
23499
55763
HPRD ID
09750
07615
Ensembl ID
ENSG00000127603
ENSG00000090989
Uniprot IDs
Q6ZSD7
Q9UPN3
Q9NV70
PDB IDs
Enriched GO Terms of Interacting Partners
?
Nervous System Development
Generation Of Neurons
Neurogenesis
Regulation Of Cell Projection Organization
Cell Projection Organization
System Development
Developmental Process
Multicellular Organismal Development
Vocalization Behavior
Protein Localization
Regulation Of Cellular Component Organization
Cellular Localization
Neuron Projection Development
Anatomical Structure Development
Membrane Organization
Synapse Assembly
Neuroligin Clustering
Organelle Organization
Response To Mechanical Stimulus
Neuron Development
Cellular Protein Localization
Gephyrin Clustering
Cell Differentiation
Signaling
Cellular Component Assembly
Cell Communication
Negative Regulation Of Filopodium Assembly
Neuron Differentiation
Regulation Of Cell Differentiation
Social Behavior
Vocal Learning
Learning
Positive Regulation Of Cell Differentiation
Postsynaptic Membrane Assembly
Regulation Of Grooming Behavior
Synapse Organization
Cell Development
Regulation Of Neuron Projection Development
Postsynaptic Density Protein 95 Clustering
Anatomical Structure Formation Involved In Morphogenesis
Auditory Behavior
Movement Of Cell Or Subcellular Component
Regulation Of Signaling
Neuronal Ion Channel Clustering
Regulation Of Cell Morphogenesis
Neuron Cell-cell Adhesion
Positive Regulation Of Cell Development
Regulation Of Binding
Cell Projection Morphogenesis
Learning Or Memory
Golgi To Plasma Membrane Transport
Movement Of Cell Or Subcellular Component
Regulation Of Cellular Component Organization
Locomotion
Nervous System Development
Post-Golgi Vesicle-mediated Transport
Microtubule-based Process
Regulation Of Cell Projection Organization
Generation Of Neurons
Regulation Of Autophagy
TOR Signaling
Organelle Organization
Golgi To Plasma Membrane Protein Transport
Neurogenesis
Regulation Of Cell Size
Regulation Of Cellular Component Size
Chemotaxis
Intracellular Signal Transduction
Cellular Component Assembly
Regulation Of Neuron Projection Development
Vesicle-mediated Transport
Autophagy
Cellular Localization
Axon Guidance
Regulation Of Neurogenesis
Positive Regulation Of Axon Extension
Autophagic Vacuole Assembly
Establishment Of Localization In Cell
Regulation Of Primitive Erythrocyte Differentiation
Lamellipodium Assembly Involved In Ameboidal Cell Migration
Lamellipodium Assembly
Microtubule Cytoskeleton Organization
Cell Projection Organization
Cell Communication
Lamellipodium Organization
Positive Regulation Of Neural Precursor Cell Proliferation
Macroautophagy
Cell Projection Morphogenesis
Regulation Of Cell Development
Extension Of A Leading Process Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration
Negative Regulation Of SNARE Complex Assembly
Cell Part Morphogenesis
Cerebral Cortex Radially Oriented Cell Migration
Axonogenesis
Regulation Of Axon Extension
Regulation Of Neuron Differentiation
Regulation Of Organelle Organization
Cell Cycle
Response To External Stimulus
Golgi Vesicle Transport
Tagcloud
?
a2
comprehensive
cytoskeleton
ecm
focal
genotypes
hbv
hbx
hcc
hepatocellular
hepg2
hmgb1
lamin
lc
migration
ms
nevertheless
obscure
platform
preliminary
profile
proteasome
proteomics
psma3
s100a11
s100a4
s100a6
supported
turn
Tagcloud (Difference)
?
a2
comprehensive
cytoskeleton
ecm
focal
genotypes
hbv
hbx
hcc
hepatocellular
hepg2
hmgb1
lamin
lc
migration
ms
nevertheless
obscure
platform
preliminary
profile
proteasome
proteomics
psma3
s100a11
s100a4
s100a6
supported
turn
Tagcloud (Intersection)
?