NOMO1 and TRIM63

Number of citations of the paper that reports this interaction (PMID 18157088)
41

Data Source:
BioGRID (two hybrid)

		NOMO1	TRIM63
Gene Name		NODAL modulator 1	tripartite motif containing 63, E3 ubiquitin protein ligase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Membrane Integral Component Of Membrane	Nucleus Cytoplasm Microtubule Z Disc M Band
	Molecular Function	Molecular_function Carbohydrate Binding	Ubiquitin-protein Transferase Activity Signal Transducer Activity Protein Binding Zinc Ion Binding Ligase Activity Titin Binding
	Biological Process	Biological_process	Muscle Contraction Signal Transduction Regulation Of Gene Expression Skeletal Muscle Atrophy Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Response To Interleukin-1 Cellular Response To Dexamethasone Stimulus
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: ATF7IP BAG6 ECT2 EXOSC10 NCLN SHBG STAT1 TOM1L1 TRIM55 TRIM63 UBQLN4 UPF2	87 interactors: ACTA1 AK1 AKR7A2 ALDOA ANKRD1 APP ATP5B ATXN3 ATXN3L BAP1 CKB CKM DCAF6 DES EEF1G EHHADH EIF3E ENO3 ESPL1 FHL2 FLNC GFM1 GMEB1 HIBADH JOSD1 LMCD1 MRPL19 MRPL41 MYBPC1 MYBPC3 MYL2 MYOT MYOZ1 NDUFA1 NEB NEBL NOMO1 NRAP OTUB1 OTUB2 PDHB PDK4 PIAS1 PIAS2 PIAS3 PKM PSMD4 PYGM SENP2 SENP3 SQSTM1 SRF STAM SUMO2 TCAP TNNC1 TNNI1 TNNI2 TNNI3 TNNT1 TNNT3 TRIM54 TRIM55 TTN UBC UBE2D1 UBE2D2 UBE2D3 UBE2I UBE2J1 UBE2U UCHL1 UCHL3 UCHL5 UQCRC1 USP13 USP15 USP2 USP21 USP28 USP33 USP4 USP5 USP7 USP8 UXT YOD1
Entrez ID		23420	84676
HPRD ID		11398	05843
Ensembl ID		ENSG00000103512	ENSG00000158022
Uniprot IDs		Q15155	B4DN95 Q969Q1
PDB IDs			2D8U 3DDT
Enriched GO Terms of Interacting Partners?		Cellular Macromolecule Catabolic Process Negative Regulation Of Macrophage Fusion Primary Spermatocyte Growth Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Negative Regulation By Virus Of Viral Protein Levels In Host Cell Negative Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Catabolic Process Negative Regulation Of Nephron Tubule Epithelial Cell Differentiation Metanephric Mesenchymal Cell Proliferation Involved In Metanephros Development Ubiquitin-dependent Protein Catabolic Process Response To Hydrogen Peroxide Modification-dependent Protein Catabolic Process Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Nuclear Polyadenylation-dependent RRNA Catabolic Process CUT Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Metanephric Mesenchymal Cell Differentiation Nuclear-transcribed MRNA Catabolic Process Cellular Protein Catabolic Process RNA Localization MRNA Catabolic Process Skeletal Muscle Atrophy Protein Catabolic Process Negative Regulation Of Syncytium Formation By Plasma Membrane Fusion Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Striated Muscle Atrophy Nuclear MRNA Surveillance Tail-anchored Membrane Protein Insertion Into ER Membrane RNA Catabolic Process Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Muscle Atrophy Response To Reactive Oxygen Species Regulation Of Proteasomal Protein Catabolic Process Protein Insertion Into ER Membrane RNA Surveillance Skeletal Muscle Adaptation Mesenchymal Cell Differentiation Involved In Kidney Development Histone MRNA Catabolic Process Regulation Of Gene Expression, Epigenetic Dosage Compensation By Inactivation Of X Chromosome Cell Proliferation Involved In Metanephros Development Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Intracellular MRNA Localization Regulation Of I-kappaB Kinase/NF-kappaB Signaling Dosage Compensation RRNA Catabolic Process Cell Differentiation Involved In Metanephros Development	Protein Modification By Small Protein Removal Muscle Filament Sliding Actin-myosin Filament Sliding Protein Deubiquitination Actin-mediated Cell Contraction Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Actin Filament-based Movement Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein K48-linked Deubiquitination Proteolysis Muscle Contraction Regulation Of Proteasomal Protein Catabolic Process Catabolic Process Muscle System Process Regulation Of Protein Catabolic Process Actin Filament-based Process Protein K63-linked Deubiquitination Striated Muscle Cell Development Striated Muscle Contraction Muscle Cell Development Muscle Structure Development Myofibril Assembly Cellular Protein Modification Process Cellular Protein Metabolic Process Regulation Of Proteolysis Cardiac Muscle Tissue Morphogenesis Striated Muscle Cell Differentiation Muscle Tissue Morphogenesis Cardiac Muscle Tissue Development Muscle Organ Morphogenesis Actomyosin Structure Organization Protein Sumoylation Protein Metabolic Process Striated Muscle Tissue Development Muscle Cell Differentiation Muscle Tissue Development Regulation Of Muscle Contraction Protein Modification By Small Protein Conjugation Muscle Organ Development Heart Morphogenesis Regulation Of Cellular Protein Metabolic Process Cardiac Myofibril Assembly Muscle Fiber Development Monoubiquitinated Protein Deubiquitination
Tagcloud ?			benzylic bioactivation clues covalent danger dapk1 hapten hepatotoxicity il22 inflammasome marks methide nevirapine nlrp3 nvp obligate oh oxidized presumably quinone ra2 rash rashes reflecting s100a7 s100a7a sulfate travels
Tagcloud (Difference) ?			benzylic bioactivation clues covalent danger dapk1 hapten hepatotoxicity il22 inflammasome marks methide nevirapine nlrp3 nvp obligate oh oxidized presumably quinone ra2 rash rashes reflecting s100a7 s100a7a sulfate travels
Tagcloud (Intersection) ?