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NOMO1 and ECT2
Number of citations of the paper that reports this interaction (PMID
22990118
)
7
Data Source:
BioGRID
(two hybrid)
NOMO1
ECT2
Gene Name
NODAL modulator 1
epithelial cell transforming 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cellular_component
Membrane
Integral Component Of Membrane
Nucleus
Cytoplasm
Cytosol
Cell-cell Junction
Tight Junction
Midbody
Nuclear Membrane
Cleavage Furrow
Intracellular Membrane-bounded Organelle
Mitotic Spindle
Centralspindlin Complex
Molecular Function
Molecular_function
Carbohydrate Binding
Signal Transducer Activity
Rho Guanyl-nucleotide Exchange Factor Activity
GTPase Activator Activity
Protein Binding
Rho GTPase Binding
Protein Homodimerization Activity
Biological Process
Biological_process
Cell Morphogenesis
Cytokinesis
Small GTPase Mediated Signal Transduction
Protein Transport
Activation Of Protein Kinase Activity
Positive Regulation Of Rho GTPase Activity
Positive Regulation Of Cytokinesis
Activation Of Rho GTPase Activity
Activation Of Rac GTPase Activity
Positive Regulation Of Protein Import Into Nucleus
Positive Regulation Of Apoptotic Process
Positive Regulation Of Cdc42 GTPase Activity
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Neuron Differentiation
Regulation Of Protein Kinase Activity
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Small GTPase Mediated Signal Transduction
Protein Homooligomerization
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Cellular Response To Hydrogen Peroxide
Tight Junction Assembly
Cellular Response To Calcium Ion
Cellular Response To Ionizing Radiation
Apoptotic Signaling Pathway
Pathways
Rho GTPase cycle
Signaling by GPCR
GPCR downstream signaling
Signalling by NGF
Cell death signalling via NRAGE, NRIF and NADE
Signaling by Rho GTPases
NRAGE signals death through JNK
G alpha (12/13) signalling events
p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
12 interactors:
ATF7IP
BAG6
ECT2
EXOSC10
NCLN
SHBG
STAT1
TOM1L1
TRIM55
TRIM63
UBQLN4
UPF2
37 interactors:
ABR
C2orf42
CCDC91
CD19
CDK1
CHST10
COX2
CRIPAK
CSTB
EIF4A2
EIF5B
ERAL1
F2RL2
FANCM
GGN
ILVBL
KLHL20
MBD1
MT2A
NOMO1
NPC2
OOSP2
OTUB1
PARD6A
PCOLCE
PLK1
POMP
PSMA6
RACGAP1
RHOG
RPS20
SNRNP200
SPATA22
TCEB1
THAP11
UBB
VDAC2
Entrez ID
23420
1894
HPRD ID
11398
11860
Ensembl ID
ENSG00000103512
ENSG00000114346
Uniprot IDs
Q15155
G5E9L8
Q9H8V3
PDB IDs
3L46
Enriched GO Terms of Interacting Partners
?
Cellular Macromolecule Catabolic Process
Negative Regulation Of Macrophage Fusion
Primary Spermatocyte Growth
Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription
Negative Regulation By Virus Of Viral Protein Levels In Host Cell
Negative Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Catabolic Process
Negative Regulation Of Nephron Tubule Epithelial Cell Differentiation
Metanephric Mesenchymal Cell Proliferation Involved In Metanephros Development
Ubiquitin-dependent Protein Catabolic Process
Response To Hydrogen Peroxide
Modification-dependent Protein Catabolic Process
Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation
Nuclear Polyadenylation-dependent RRNA Catabolic Process
CUT Catabolic Process
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Metanephric Mesenchymal Cell Differentiation
Nuclear-transcribed MRNA Catabolic Process
Cellular Protein Catabolic Process
RNA Localization
MRNA Catabolic Process
Skeletal Muscle Atrophy
Protein Catabolic Process
Negative Regulation Of Syncytium Formation By Plasma Membrane Fusion
Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis
Striated Muscle Atrophy
Nuclear MRNA Surveillance
Tail-anchored Membrane Protein Insertion Into ER Membrane
RNA Catabolic Process
Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly
Muscle Atrophy
Response To Reactive Oxygen Species
Regulation Of Proteasomal Protein Catabolic Process
Protein Insertion Into ER Membrane
RNA Surveillance
Skeletal Muscle Adaptation
Mesenchymal Cell Differentiation Involved In Kidney Development
Histone MRNA Catabolic Process
Regulation Of Gene Expression, Epigenetic
Dosage Compensation By Inactivation Of X Chromosome
Cell Proliferation Involved In Metanephros Development
Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis
Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation
Intracellular MRNA Localization
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Dosage Compensation
RRNA Catabolic Process
Cell Differentiation Involved In Metanephros Development
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Ubiquitination
Cellular Macromolecule Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Cell Cycle
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of Proteolysis
Negative Regulation Of Transferase Activity
Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
DNA Damage Checkpoint
Modification-dependent Protein Catabolic Process
Mitotic Cell Cycle Checkpoint
Proteolysis Involved In Cellular Protein Catabolic Process
Viral Process
Cellular Protein Catabolic Process
Response To Stress
Cellular Response To DNA Damage Stimulus
Regulation Of Apoptotic Process
Protein Catabolic Process
Cellular Response To Stress
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Cell Death
Positive Regulation Of Protein Catabolic Process
Negative Regulation Of Mitotic Cell Cycle
Positive Regulation Of Cell Cycle Process
Neurotrophin Signaling Pathway
Regulation Of Cell Cycle
Regulation Of Cellular Protein Metabolic Process
Cell Cycle Checkpoint
Regulation Of Proteolysis
Regulation Of Catalytic Activity
Mitotic DNA Damage Checkpoint
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Mitotic DNA Integrity Checkpoint
Negative Regulation Of Cell Cycle
Negative Regulation Of Protein Ubiquitination
Mitotic Cell Cycle Phase Transition
Cell Cycle
Cell Cycle Phase Transition
Tagcloud
?
broader
correlate
correlates
cytoskeleton
dbl
dbs
deregulated
encodes
exchange
family
gtpases
guanine
jun
lfc
lsc
mpk2
nh2
oncogenes
panel
possess
rho
sets
specificities
structurally
transformed
transforming
utilization
versions
weakly
Tagcloud (Difference)
?
broader
correlate
correlates
cytoskeleton
dbl
dbs
deregulated
encodes
exchange
family
gtpases
guanine
jun
lfc
lsc
mpk2
nh2
oncogenes
panel
possess
rho
sets
specificities
structurally
transformed
transforming
utilization
versions
weakly
Tagcloud (Intersection)
?