NOMO1 and EXOSC10

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NOMO1	EXOSC10
Gene Name		NODAL modulator 1	exosome component 10
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Membrane Integral Component Of Membrane	Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Nucleus Nucleoplasm Nucleolus Cytoplasm Membrane Transcriptionally Active Chromatin
	Molecular Function	Molecular_function Carbohydrate Binding	Nucleotide Binding Exoribonuclease Activity Protein Binding 3'-5' Exonuclease Activity Poly(A) RNA Binding
	Biological Process	Biological_process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Maturation Of 5.8S RRNA Nuclear-transcribed MRNA Catabolic Process Dosage Compensation By Inactivation Of X Chromosome Nuclear MRNA Surveillance CUT Catabolic Process Nuclear Polyadenylation-dependent RRNA Catabolic Process Histone MRNA Catabolic Process Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: ATF7IP BAG6 ECT2 EXOSC10 NCLN SHBG STAT1 TOM1L1 TRIM55 TRIM63 UBQLN4 UPF2	35 interactors: ALDH1B1 B9D1 CHPF CIB1 DIS3 DXO EIF3M EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 FERMT3 FOXRED1 IMMT LCAT LSM2 LSM8 MPHOSPH6 MPP6 NOMO1 NOMO2 PTGES2 RPE RUVBL2 SCRIB SKIV2L SSRP1 TARDBP TOX4 UPF2 USP16 USP21 XRN1 XRN2
Entrez ID		23420	5394
HPRD ID		11398	16180
Ensembl ID		ENSG00000103512	ENSG00000171824
Uniprot IDs		Q15155	Q01780 Q96G78
PDB IDs			2CPR 3SAF 3SAG 3SAH
Enriched GO Terms of Interacting Partners?		Cellular Macromolecule Catabolic Process Negative Regulation Of Macrophage Fusion Primary Spermatocyte Growth Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Negative Regulation By Virus Of Viral Protein Levels In Host Cell Negative Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Catabolic Process Negative Regulation Of Nephron Tubule Epithelial Cell Differentiation Metanephric Mesenchymal Cell Proliferation Involved In Metanephros Development Ubiquitin-dependent Protein Catabolic Process Response To Hydrogen Peroxide Modification-dependent Protein Catabolic Process Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Nuclear Polyadenylation-dependent RRNA Catabolic Process CUT Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Metanephric Mesenchymal Cell Differentiation Nuclear-transcribed MRNA Catabolic Process Cellular Protein Catabolic Process RNA Localization MRNA Catabolic Process Skeletal Muscle Atrophy Protein Catabolic Process Negative Regulation Of Syncytium Formation By Plasma Membrane Fusion Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Striated Muscle Atrophy Nuclear MRNA Surveillance Tail-anchored Membrane Protein Insertion Into ER Membrane RNA Catabolic Process Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Muscle Atrophy Response To Reactive Oxygen Species Regulation Of Proteasomal Protein Catabolic Process Protein Insertion Into ER Membrane RNA Surveillance Skeletal Muscle Adaptation Mesenchymal Cell Differentiation Involved In Kidney Development Histone MRNA Catabolic Process Regulation Of Gene Expression, Epigenetic Dosage Compensation By Inactivation Of X Chromosome Cell Proliferation Involved In Metanephros Development Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Intracellular MRNA Localization Regulation Of I-kappaB Kinase/NF-kappaB Signaling Dosage Compensation RRNA Catabolic Process Cell Differentiation Involved In Metanephros Development	Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic RNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process MRNA Metabolic Process RRNA Metabolic Process RRNA Processing Aromatic Compound Catabolic Process Cellular Macromolecule Catabolic Process Ribosome Biogenesis Ribonucleoprotein Complex Biogenesis RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Catabolic Process RNA Metabolic Process NcRNA Metabolic Process Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Nuclear MRNA Surveillance Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Deamination RNA Surveillance Nucleic Acid Phosphodiester Bond Hydrolysis RNA Phosphodiester Bond Hydrolysis Gene Expression Maturation Of 5.8S RRNA Histone MRNA Catabolic Process RRNA Catabolic Process Cellular Metabolic Process DNA Modification Protein K63-linked Deubiquitination Histone Deubiquitination Histone MRNA Metabolic Process DNA Metabolic Process Chromatin Modification Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Male Germ Cell Proliferation Metabolic Process Chromatin Remodeling MRNA Processing Regulation Of RNA Stability Chromatin Organization Thrombopoietin-mediated Signaling Pathway Posttranscriptional Regulation Of Gene Expression Histone H2A K63-linked Deubiquitination Regulation Of Male Germ Cell Proliferation Endomitotic Cell Cycle
Tagcloud ?			18s adopt assumed candidates carry defects exosome extensively functionally fundamental hela homolog its2 itss nucleolar polycistronic posing precede precursors processing recruit ribosomopathies rnas rrna rrnas rrp6 spacers transcribed yeast
Tagcloud (Difference) ?			18s adopt assumed candidates carry defects exosome extensively functionally fundamental hela homolog its2 itss nucleolar polycistronic posing precede precursors processing recruit ribosomopathies rnas rrna rrnas rrp6 spacers transcribed yeast
Tagcloud (Intersection) ?