NOMO1 and TOM1L1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NOMO1	TOM1L1
Gene Name		NODAL modulator 1	target of myb1 (chicken)-like 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Membrane Integral Component Of Membrane	Cytoplasm Lysosome Endosome Golgi Stack Cytosol Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Molecular_function Carbohydrate Binding	Protein Binding SH3 Domain Binding Protein Kinase Binding Clathrin Binding Protein Kinase Activator Activity Ubiquitin Binding
	Biological Process	Biological_process	Intracellular Protein Transport Signal Transduction Positive Regulation Of Protein Autophosphorylation Activation Of Protein Kinase Activity Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Mitotic Nuclear Division Regulation Of DNA Biosynthetic Process
Pathways
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		12 interactors: ATF7IP BAG6 ECT2 EXOSC10 NCLN SHBG STAT1 TOM1L1 TRIM55 TRIM63 UBQLN4 UPF2	27 interactors: AMFR CCDC47 CELF1 COPS7A CWF19L1 FAM208A FYN GLUD2 GRB2 GSN HGS HNRNPH1 MAP3K3 NDC80 NOMO1 PDPN PELP1 PHYH PIK3R1 PWP2 RAB18 TOLLIP TSG101 TUBA1B UBXN4 VAV2 VCP
Entrez ID		23420	10040
HPRD ID		11398	05266
Ensembl ID		ENSG00000103512	ENSG00000141198
Uniprot IDs		Q15155	B7Z9E2 I3L4I4 O75674
PDB IDs			3RRU
Enriched GO Terms of Interacting Partners?		Cellular Macromolecule Catabolic Process Negative Regulation Of Macrophage Fusion Primary Spermatocyte Growth Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Negative Regulation By Virus Of Viral Protein Levels In Host Cell Negative Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Catabolic Process Negative Regulation Of Nephron Tubule Epithelial Cell Differentiation Metanephric Mesenchymal Cell Proliferation Involved In Metanephros Development Ubiquitin-dependent Protein Catabolic Process Response To Hydrogen Peroxide Modification-dependent Protein Catabolic Process Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Nuclear Polyadenylation-dependent RRNA Catabolic Process CUT Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Metanephric Mesenchymal Cell Differentiation Nuclear-transcribed MRNA Catabolic Process Cellular Protein Catabolic Process RNA Localization MRNA Catabolic Process Skeletal Muscle Atrophy Protein Catabolic Process Negative Regulation Of Syncytium Formation By Plasma Membrane Fusion Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Striated Muscle Atrophy Nuclear MRNA Surveillance Tail-anchored Membrane Protein Insertion Into ER Membrane RNA Catabolic Process Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Muscle Atrophy Response To Reactive Oxygen Species Regulation Of Proteasomal Protein Catabolic Process Protein Insertion Into ER Membrane RNA Surveillance Skeletal Muscle Adaptation Mesenchymal Cell Differentiation Involved In Kidney Development Histone MRNA Catabolic Process Regulation Of Gene Expression, Epigenetic Dosage Compensation By Inactivation Of X Chromosome Cell Proliferation Involved In Metanephros Development Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Intracellular MRNA Localization Regulation Of I-kappaB Kinase/NF-kappaB Signaling Dosage Compensation RRNA Catabolic Process Cell Differentiation Involved In Metanephros Development	Phosphatidylinositol-mediated Signaling Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Response To Endoplasmic Reticulum Stress Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Platelet Activation Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Neurotrophin TRK Receptor Signaling Pathway T Cell Costimulation Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Response To Organic Substance Phagocytosis Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of RNA Splicing Fc Receptor Signaling Pathway ER-nucleus Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Activation Wound Healing Response To Unfolded Protein Response To Stress Intracellular Signal Transduction Cellular Response To Organic Substance Cellular Component Assembly Immune Response-regulating Cell Surface Receptor Signaling Pathway Vesicle-mediated Transport Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Activation Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Complex Assembly Response To Wounding ER-associated Ubiquitin-dependent Protein Catabolic Process Blood Coagulation Hemostasis Cellular Response To Stimulus Cellular Response To Fibroblast Growth Factor Stimulus Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Response To Fibroblast Growth Factor Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination NFAT Protein Import Into Nucleus Regulation Of Phosphatidylinositol 3-kinase Activity Negative Regulation Of ERBB Signaling Pathway Signal Transduction Immune Response-regulating Signaling Pathway Positive Regulation Of T Cell Activation
Tagcloud ?			adaptor behave bridged clathrin cytosolic defective egf egfr elusive endocytic endocytosis endosome engage exogenous grb2 incapable knocked machinery onto participate redistributes rescue rnai shc stimulates tail transient triggers tyr
Tagcloud (Difference) ?			adaptor behave bridged clathrin cytosolic defective egf egfr elusive endocytic endocytosis endosome engage exogenous grb2 incapable knocked machinery onto participate redistributes rescue rnai shc stimulates tail transient triggers tyr
Tagcloud (Intersection) ?