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MAPRE3 and AURKB
Number of citations of the paper that reports this interaction (PMID
19696028
)
13
Data Source:
BioGRID
(affinity chromatography technology, enzymatic study)
MAPRE3
AURKB
Gene Name
microtubule-associated protein, RP/EB family, member 3
aurora kinase B
Image
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytoplasmic Microtubule
Microtubule Cytoskeleton
Midbody
Microtubule Plus-end
Perinuclear Region Of Cytoplasm
Condensed Chromosome, Centromeric Region
Condensed Nuclear Chromosome, Centromeric Region
Nucleus
Spindle
Cytosol
Spindle Microtubule
Chromocenter
Midbody
Spindle Pole Centrosome
Chromosome Passenger Complex
Spindle Midzone
Molecular Function
Protein Binding
Microtubule Binding
Protein Serine/threonine Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Binding
ATP Binding
Histone Serine Kinase Activity
Metal Ion Binding
Biological Process
Mitotic Nuclear Division
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Transcription, DNA-templated
Cell Division
Positive Regulation Of Microtubule Plus-end Binding
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Mitotic Cell Cycle
Negative Regulation Of B Cell Apoptotic Process
Protein Phosphorylation
Aging
Cell Proliferation
Attachment Of Spindle Microtubules To Kinetochore
Abscission
Histone Modification
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Spindle Checkpoint
Negative Regulation Of Protein Binding
Negative Regulation Of Cytokinesis
Positive Regulation Of Cytokinesis
Protein Localization To Kinetochore
Cellular Response To UV
Cleavage Furrow Formation
Spindle Stabilization
Histone H3-S28 Phosphorylation
Protein Autophosphorylation
Mitotic Spindle Midzone Assembly
Regulation Of Chromosome Segregation
Pathways
Mitotic Prometaphase
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of mitotic cell cycle
Mitotic Anaphase
Mitotic Metaphase and Anaphase
APC/C-mediated degradation of cell cycle proteins
Cell Cycle, Mitotic
M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions
16 interactors:
APC2
AURKA
AURKB
CLASP1
EIF4E2
JUN
LMO2
MAPRE1
MAPRE2
PSMA1
PSMB1
RAB1A
SDCBP
SIAH1
TROAP
TXN2
48 interactors:
AJUBA
ANKZF1
APP
BCL2L11
BIRC5
CBX3
CDCA8
CENPA
CIB1
CYLD
DCUN1D1
DES
EVI5
FBXL2
FLOT1
GFAP
GNB2L1
GSG2
HIST1H3A
HIST2H3C
HIST3H3
INCENP
KIF20A
KLHL13
KLHL21
KLHL9
LATS1
LATS2
MAPRE1
MAPRE2
MAPRE3
NCAPH
NDC80
NSUN2
NUF2
PPP2R4
PSMA3
RACGAP1
RASA1
RASSF1
SEPT1
SKA1
SKA3
SUMO1
SUMO2
TACC1
TBL3
TGFBR1
Entrez ID
22924
9212
HPRD ID
16156
05397
Ensembl ID
ENSG00000084764
ENSG00000178999
Uniprot IDs
Q9UPY8
Q96GD4
PDB IDs
1WYO
3CO1
3TQ7
4AF3
Enriched GO Terms of Interacting Partners
?
Mitotic Cell Cycle
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cell Cycle
Mitotic Cell Cycle Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Negative Regulation Of Microtubule Polymerization Or Depolymerization
Mitotic Nuclear Division
Cell Cycle Process
Regulation Of Microtubule Polymerization Or Depolymerization
Cell Division
Ubiquitin-dependent Protein Catabolic Process
Mitotic Cell Cycle Phase Transition
Modification-dependent Protein Catabolic Process
Cell Cycle Phase Transition
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Negative Regulation Of Microtubule Depolymerization
Protein Catabolic Process
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Regulation Of Microtubule Cytoskeleton Organization
Spindle Stabilization
Positive Regulation Of Cellular Protein Catabolic Process
Negative Regulation Of Cytoskeleton Organization
Regulation Of Microtubule-based Process
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Negative Regulation Of Cell Cycle
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Protein Catabolic Process
Regulation Of Cell Cycle Process
Positive Regulation Of Cell Cycle Process
Cellular Macromolecule Catabolic Process
Cellular Protein Localization
Cell Cycle Checkpoint
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Regulation Of Organelle Organization
Regulation Of Cell Cycle
Regulation Of Binding
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Cell Cycle
Histone-serine Phosphorylation
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Protein Complex Disassembly
Positive Regulation Of Proteolysis
Negative Regulation Of Binding
Negative Regulation Of Protein Ubiquitination
Cell Cycle
Cell Division
Mitotic Cell Cycle
Mitotic Cell Cycle Process
Cell Cycle Process
Mitotic Nuclear Division
Organelle Organization
Chromosome Segregation
Cytokinesis
Regulation Of Cell Cycle
Regulation Of Microtubule-based Process
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Microtubule Cytoskeleton Organization
Sister Chromatid Segregation
Mitotic Spindle Organization
Microtubule Cytoskeleton Organization
Regulation Of Cellular Component Organization
Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Complex Assembly
Positive Regulation Of Microtubule Plus-end Binding
Regulation Of Cytoskeleton Organization
Cellular Localization
Protein Complex Localization
Regulation Of Organelle Organization
Regulation Of Signaling
Regulation Of Signal Transduction
Regulation Of Protein Metabolic Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Regulation Of Microtubule Polymerization Or Depolymerization
Microtubule-based Process
Cellular Process
Mitotic Sister Chromatid Segregation
Positive Regulation Of Cell Cycle
Regulation Of Protein Localization
Protein Modification By Small Protein Conjugation
Positive Regulation Of Proteolysis
Positive Regulation Of Catalytic Activity
Regulation Of Catalytic Activity
Negative Regulation Of Wnt Signaling Pathway
Regulation Of Cell Cycle Process
Cytoskeleton Organization
Positive Regulation Of Protein Modification Process
Regulation Of Protein Kinase Activity
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cytokinesis
Negative Regulation Of Catalytic Activity
Spindle Organization
Negative Regulation Of Cellular Metabolic Process
Tagcloud
?
allele
birc5
cdca8
consortium
contribution
cpc
division
european
exon
familial
fifteen
fixed
genotyped
incenp
inherited
investigates
meta
modest
passenger
pivotal
rs1675126
rs2071214
snp
snps
spite
sporadic
synonymous
top
variability
Tagcloud (Difference)
?
allele
birc5
cdca8
consortium
contribution
cpc
division
european
exon
familial
fifteen
fixed
genotyped
incenp
inherited
investigates
meta
modest
passenger
pivotal
rs1675126
rs2071214
snp
snps
spite
sporadic
synonymous
top
variability
Tagcloud (Intersection)
?