MAPRE3 and SPDYE2B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MAPRE3	SPDYE2B
Description		microtubule associated protein RP/EB family member 3	speedy/RINGO cell cycle regulator family member E2B
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Cytoskeleton Microtubule Cytoplasmic Microtubule Microtubule Cytoskeleton Midbody Microtubule Plus-end Perinuclear Region Of Cytoplasm Spindle Midzone Neuron To Neuron Synapse Mitotic Spindle Astral Microtubule End Microtubule End
	Molecular Function	Protein Binding Microtubule Binding Identical Protein Binding Protein Serine/threonine Kinase Activator Activity Microtubule Plus-end Binding Protein Serine/threonine Kinase Binding	Protein Kinase Binding
	Biological Process	Intracellular Protein Localization Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule Polymerization Protein Localization To Microtubule Positive Regulation Of DNA-templated Transcription Behavioral Response To Cocaine Spindle Assembly Cell Division Positive Regulation Of Dendritic Spine Morphogenesis
Pathways
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Estimated glomerular filtration rate in non-diabetics ( 31451708) Left–right brain asymmetry ( 33723403) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Post bronchodilator FEV1/FVC ratio ( 26634245) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		56 interacting genes: ANKRD1 APC2 AURKA AURKB C20orf202 CCSER1 CHRDL2 CLASP1 CRTAC1 DCTN2 DDIT4L DOK4 EIF4E2 FAM161B FOXD4L1 FOXD4L4 FXR2 GTF2F2 GTSE1 HROB IKZF1 JUN KIF19 KLHDC7B KNSTRN LAP3 LHX4 LMO2 MAPRE2 MARCHF7 MEOX2 MRPL12 PDE4DIP PICK1 POU4F1 PSMA1 PSMB1 PSRC1 RAB1A REL SDCBP SIAH1 SLAIN1 SPDYE2 SPDYE2B SPMIP10 SPMIP2 TLE5 TRAIP TRIM14 TXN2 YAF2 ZC2HC1A ZC2HC1C ZNF526 ZNF547	4 interacting genes: APPBP2 KRTAP17-1 MAPRE1 MAPRE3
Entrez ID		22924	100310812
HPRD ID		16156
Ensembl ID		ENSG00000084764	ENSG00000173678
Uniprot IDs		Q9UPY8	A6NHP3
PDB IDs		1WYO 3CO1 3JAK 3JAL 3JAR 3TQ7 7SJ9
Enriched GO Terms of Interacting Partners?		Regulation Of Microtubule Polymerization Or Depolymerization Microtubule-based Process Microtubule Cytoskeleton Organization Spindle Organization Regulation Of Microtubule Cytoskeleton Organization Cytoplasmic Microtubule Microtubule Plus-end Microtubule Cytoskeleton Regulation Of Microtubule-based Process Positive Regulation Of Microtubule Polymerization Cytoskeleton Spindle Microtubule Cytoskeleton Organization Microtubule Microtubule Organizing Center Plasma Membrane Bounded Cell Projection Organization Microtubule Plus-end Binding Cytoplasmic Microtubule Organization Regulation Of Microtubule Polymerization Spindle Midzone Protein Binding Cell Projection Organization Chromosome Passenger Complex Positive Regulation Of Protein Polymerization Microtubule Binding Kinetochore Mitotic Spindle Organization Spindle Assembly Positive Regulation Of Supramolecular Fiber Organization Regulation Of Microtubule Depolymerization Regulation Of Supramolecular Fiber Organization Regulation Of Cytoskeleton Organization Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Epithelial Cell Migration Cilium Disassembly Protein Localization To Cytoskeleton Astral Microtubule Organization Beta-catenin Destruction Complex Regulation Of Signal Transduction By P53 Class Mediator Microtubule Cytoskeleton Organization Involved In Mitosis Negative Regulation Of Interferon-beta Production Positive Regulation Of Organelle Organization Regulation Of Organelle Organization Regulation Of Epithelial Cell Migration	Mitotic Spindle Astral Microtubule End Protein Localization To Microtubule Microtubule Plus-end Microtubule Plus-end Binding Spindle Midzone Protein Serine/threonine Kinase Binding Microtubule Protein Localization To Cytoskeleton Cytoplasmic Microtubule Regulation Of Microtubule Polymerization Microtubule Organizing Center Spindle Assembly Regulation Of Microtubule Polymerization Or Depolymerization Protein Localization To Astral Microtubule Protein Localization To Mitotic Spindle Protein Localization To Spindle Microtubule Spindle Organization Regulation Of Microtubule Cytoskeleton Organization Cortical Microtubule Cytoskeleton Regulation Of Microtubule-based Process Microtubule Binding Microtubule Cytoskeleton Microtubule End Membraneless Organelle Assembly Neuron To Neuron Synapse Cytoskeleton Regulation Of Supramolecular Fiber Organization Cell Projection Membrane Negative Regulation Of Microtubule Polymerization Intracellular Protein Localization Microtubule Cytoskeleton Organization Regulation Of Protein-containing Complex Assembly Cell Division Mitotic Spindle Microtubule Behavioral Response To Cocaine Cul2-RING Ubiquitin Ligase Complex Positive Regulation Of Dendritic Spine Morphogenesis Attachment Of Mitotic Spindle Microtubules To Kinetochore Microtubule Polymerization Regulation Of Cytoskeleton Organization Protein Localization To Centrosome Microtubule Associated Complex Protein Localization To Organelle Positive Regulation Of Microtubule Polymerization Mitotic Spindle Pole Microtubule Polymerization Or Depolymerization Attachment Of Spindle Microtubules To Kinetochore Establishment Of Mitotic Spindle Orientation Positive Regulation Of Dendrite Morphogenesis Positive Regulation Of Dendritic Spine Development
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