MAPRE3 and CLASP1

Number of citations of the paper that reports this interaction (PMID 15631994)
101

Data Source:
HPRD (in vivo, in vitro)

		MAPRE3	CLASP1
Gene Name		microtubule-associated protein, RP/EB family, member 3	cytoplasmic linker associated protein 1
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoplasmic Microtubule Microtubule Cytoskeleton Midbody Microtubule Plus-end Perinuclear Region Of Cytoplasm	Kinetochore Condensed Chromosome Kinetochore Golgi Apparatus Centrosome Kinetochore Microtubule Cytosol Spindle Microtubule Cytoplasmic Microtubule Cell Cortex Membrane Cortical Microtubule Cytoskeleton Centrosomal Corona Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding Microtubule Binding Kinetochore Binding Microtubule Plus-end Binding
	Biological Process	Mitotic Nuclear Division Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Transcription, DNA-templated Cell Division Positive Regulation Of Microtubule Plus-end Binding	G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule Bundle Formation Organelle Organization Microtubule Nucleation Negative Regulation Of Microtubule Depolymerization Establishment Or Maintenance Of Cell Polarity Axon Guidance Exit From Mitosis Microtubule Organizing Center Organization Negative Regulation Of Microtubule Polymerization Or Depolymerization Microtubule Anchoring Establishment Of Spindle Orientation Cell Division
Pathways			Role of Abl in Robo-Slit signaling Mitotic Prometaphase Organelle biogenesis and maintenance Axon guidance Separation of Sister Chromatids Assembly of the primary cilium G2/M Transition Mitotic Anaphase Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane M Phase Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Resolution of Sister Chromatid Cohesion Loss of Nlp from mitotic centrosomes Centrosome maturation Signaling by Robo receptor Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: APC2 AURKA AURKB CLASP1 EIF4E2 JUN LMO2 MAPRE1 MAPRE2 PSMA1 PSMB1 RAB1A SDCBP SIAH1 TROAP TXN2	5 interactors: CLIP2 JAKMIP2 MAPRE1 MAPRE3 YWHAG
Entrez ID		22924	23332
HPRD ID		16156	09322
Ensembl ID		ENSG00000084764	ENSG00000074054
Uniprot IDs		Q9UPY8	A2RU21 B7ZLX3 Q7Z460
PDB IDs		1WYO 3CO1 3TQ7	4K92
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Cell Cycle Mitotic Cell Cycle Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Negative Regulation Of Microtubule Polymerization Or Depolymerization Mitotic Nuclear Division Cell Cycle Process Regulation Of Microtubule Polymerization Or Depolymerization Cell Division Ubiquitin-dependent Protein Catabolic Process Mitotic Cell Cycle Phase Transition Modification-dependent Protein Catabolic Process Cell Cycle Phase Transition Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Negative Regulation Of Microtubule Depolymerization Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Microtubule Cytoskeleton Organization Spindle Stabilization Positive Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cytoskeleton Organization Regulation Of Microtubule-based Process Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Negative Regulation Of Cell Cycle Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Protein Catabolic Process Regulation Of Cell Cycle Process Positive Regulation Of Cell Cycle Process Cellular Macromolecule Catabolic Process Cellular Protein Localization Cell Cycle Checkpoint Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Regulation Of Organelle Organization Regulation Of Cell Cycle Regulation Of Binding Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Cell Cycle Histone-serine Phosphorylation Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Complex Disassembly Positive Regulation Of Proteolysis Negative Regulation Of Binding Negative Regulation Of Protein Ubiquitination	Positive Regulation Of Microtubule Plus-end Binding Positive Regulation Of Protein Binding Mitotic Cell Cycle Process Mitotic Cell Cycle G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Binding Cell Cycle Process Regulation Of Protein Binding Cell Cycle Regulation Of Binding Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Nuclear Division Protein Localization To Microtubule Cell Division Negative Regulation Of Microtubule Polymerization Organelle Organization Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Localization To Cytoskeleton Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Microtubule Polymerization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Organelle Organization Regulation Of Protein Phosphorylation Negative Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of Mitochondrion Organization Regulation Of Phosphorylation Regulation Of Microtubule Polymerization Or Depolymerization Cellular Protein Localization Negative Regulation Of Protein Polymerization Regulation Of Phosphorus Metabolic Process Regulation Of Mitochondrion Organization Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Tagcloud ?			clip1 cranial cytoskeleton ectoderm ectodermal embryogenesis gastrulation glued hemisphere involuting laevis lis1 maternally mesoderm microtubule microtubules movements nerves neurogenesis p150 persists platforms progresses stim1 tip tips tracking vertebrate xenopus
Tagcloud (Difference) ?			clip1 cranial cytoskeleton ectoderm ectodermal embryogenesis gastrulation glued hemisphere involuting laevis lis1 maternally mesoderm microtubule microtubules movements nerves neurogenesis p150 persists platforms progresses stim1 tip tips tracking vertebrate xenopus
Tagcloud (Intersection) ?