MAPRE3 and POU4F1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MAPRE3	POU4F1
Description		microtubule associated protein RP/EB family member 3	POU class 4 homeobox 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Cytoskeleton Microtubule Cytoplasmic Microtubule Microtubule Cytoskeleton Midbody Microtubule Plus-end Perinuclear Region Of Cytoplasm Spindle Midzone Neuron To Neuron Synapse Mitotic Spindle Astral Microtubule End Microtubule End	Chromatin Nucleus Nucleoplasm Cytoplasm Neuron Projection RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Protein Binding Microtubule Binding Identical Protein Binding Protein Serine/threonine Kinase Activator Activity Microtubule Plus-end Binding Protein Serine/threonine Kinase Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Single-stranded DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding GTPase Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Intracellular Protein Localization Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule Polymerization Protein Localization To Microtubule Positive Regulation Of DNA-templated Transcription Behavioral Response To Cocaine Spindle Assembly Cell Division Positive Regulation Of Dendritic Spine Morphogenesis	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Suckling Behavior Ventricular Compact Myocardium Morphogenesis Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Nervous System Development Axonogenesis Synapse Assembly Mesoderm Development Heart Development Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Cell Migration In Hindbrain Trigeminal Nerve Development Central Nervous System Neuron Differentiation Habenula Development Neuron Differentiation Neuron Projection Development Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Osteoclast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Neuron Fate Specification Sensory System Development Peripheral Nervous System Neuron Differentiation Peripheral Nervous System Neuron Development Regulation Of Neurogenesis Regulation Of DNA-binding Transcription Factor Activity Proprioception Involved In Equilibrioception Neuron Apoptotic Process Regulation Of Cell Cycle Innervation Cellular Response To Cytokine Stimulus Cellular Response To Estradiol Stimulus Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Transcription Regulatory Region DNA Binding
Pathways			Regulation of TP53 Activity through Association with Co-factors
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Estimated glomerular filtration rate in non-diabetics ( 31451708) Left–right brain asymmetry ( 33723403) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Post bronchodilator FEV1/FVC ratio ( 26634245) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Antipsychotic drug-induced weight gain in schizophrenia ( 31447353) Total ventricular volume (Alzheimer's disease interaction) ( 21116278)
Interacting Genes		56 interacting genes: ANKRD1 APC2 AURKA AURKB C20orf202 CCSER1 CHRDL2 CLASP1 CRTAC1 DCTN2 DDIT4L DOK4 EIF4E2 FAM161B FOXD4L1 FOXD4L4 FXR2 GTF2F2 GTSE1 HROB IKZF1 JUN KIF19 KLHDC7B KNSTRN LAP3 LHX4 LMO2 MAPRE2 MARCHF7 MEOX2 MRPL12 PDE4DIP PICK1 POU4F1 PSMA1 PSMB1 PSRC1 RAB1A REL SDCBP SIAH1 SLAIN1 SPDYE2 SPDYE2B SPMIP10 SPMIP2 TLE5 TRAIP TRIM14 TXN2 YAF2 ZC2HC1A ZC2HC1C ZNF526 ZNF547	4 interacting genes: ESR1 EWSR1 MAPRE3 RIT2
Entrez ID		22924	5457
HPRD ID		16156	03379
Ensembl ID		ENSG00000084764	ENSG00000152192
Uniprot IDs		Q9UPY8	Q01851
PDB IDs		1WYO 3CO1 3JAK 3JAL 3JAR 3TQ7 7SJ9
Enriched GO Terms of Interacting Partners?		Regulation Of Microtubule Polymerization Or Depolymerization Microtubule-based Process Microtubule Cytoskeleton Organization Spindle Organization Regulation Of Microtubule Cytoskeleton Organization Cytoplasmic Microtubule Microtubule Plus-end Microtubule Cytoskeleton Regulation Of Microtubule-based Process Positive Regulation Of Microtubule Polymerization Cytoskeleton Spindle Microtubule Cytoskeleton Organization Microtubule Microtubule Organizing Center Plasma Membrane Bounded Cell Projection Organization Microtubule Plus-end Binding Cytoplasmic Microtubule Organization Regulation Of Microtubule Polymerization Spindle Midzone Protein Binding Cell Projection Organization Chromosome Passenger Complex Positive Regulation Of Protein Polymerization Microtubule Binding Kinetochore Mitotic Spindle Organization Spindle Assembly Positive Regulation Of Supramolecular Fiber Organization Regulation Of Microtubule Depolymerization Regulation Of Supramolecular Fiber Organization Regulation Of Cytoskeleton Organization Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Epithelial Cell Migration Cilium Disassembly Protein Localization To Cytoskeleton Astral Microtubule Organization Beta-catenin Destruction Complex Regulation Of Signal Transduction By P53 Class Mediator Microtubule Cytoskeleton Organization Involved In Mitosis Negative Regulation Of Interferon-beta Production Positive Regulation Of Organelle Organization Regulation Of Organelle Organization Regulation Of Epithelial Cell Migration	Calmodulin Binding Nuclear Estrogen Receptor Activity Regulation Of Branching Involved In Prostate Gland Morphogenesis TFIIB-class Transcription Factor Binding Prostate Epithelial Cord Elongation Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Nitric-oxide Synthase Activity Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis Mammary Gland Branching Involved In Pregnancy Regulation Of Gene Expression Antral Ovarian Follicle Growth Regulation Of Nitric-oxide Synthase Activity Identical Protein Binding Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Positive Regulation Of Neuron Projection Development Dendritic Tree Mitotic Spindle Astral Microtubule End Microtubule End Nitric-oxide Synthase Regulator Activity Neuron To Neuron Synapse Branching Involved In Prostate Gland Morphogenesis Regulation Of Macromolecule Metabolic Process Estrogen Response Element Binding Prostate Gland Growth Regulation Of Canonical NF-kappaB Signal Transduction Vagina Development Regulation Of Cdc42 Protein Signal Transduction Branching Involved In Mammary Gland Duct Morphogenesis Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Cellular Response To Estrogen Stimulus Branch Elongation Of An Epithelium Axis Elongation Mammary Gland Alveolus Development Negative Regulation Of Smooth Muscle Cell Apoptotic Process Mammary Gland Epithelial Cell Proliferation Regulation Of RNA Biosynthetic Process Female Genitalia Development Regulation Of Metabolic Process Golgi Apparatus Regulation Of Oxidoreductase Activity Positive Regulation Of Cell Projection Organization Protein Localization To Microtubule Behavioral Response To Cocaine Positive Regulation Of Dendritic Spine Morphogenesis Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Prostate Gland Epithelium Morphogenesis Estrogen Receptor Signaling Pathway
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