MAPRE3 and MAPRE2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		MAPRE3	MAPRE2
Gene Name		microtubule-associated protein, RP/EB family, member 3	microtubule-associated protein, RP/EB family, member 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoplasmic Microtubule Microtubule Cytoskeleton Midbody Microtubule Plus-end Perinuclear Region Of Cytoplasm	Cytoplasm Microtubule Cytoskeleton Microtubule Plus-end
	Molecular Function	Protein Binding Microtubule Binding	Microtubule Binding
	Biological Process	Mitotic Nuclear Division Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Transcription, DNA-templated Cell Division Positive Regulation Of Microtubule Plus-end Binding	Mitotic Nuclear Division Signal Transduction Cell Proliferation Cell Division
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: APC2 AURKA AURKB CLASP1 EIF4E2 JUN LMO2 MAPRE1 MAPRE2 PSMA1 PSMB1 RAB1A SDCBP SIAH1 TROAP TXN2	17 interactors: APC APP AURKA AURKB CDK2 CDK4 CLASP2 CLIP1 CRTAC1 LMO2 MAPRE1 MAPRE3 NIF3L1 PAXIP1 TRAF1 TRAIP TXN2
Entrez ID		22924	10982
HPRD ID		16156	16157
Ensembl ID		ENSG00000084764	ENSG00000166974
Uniprot IDs		Q9UPY8	G5E9I6 Q15555
PDB IDs		1WYO 3CO1 3TQ7
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Cell Cycle Mitotic Cell Cycle Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Negative Regulation Of Microtubule Polymerization Or Depolymerization Mitotic Nuclear Division Cell Cycle Process Regulation Of Microtubule Polymerization Or Depolymerization Cell Division Ubiquitin-dependent Protein Catabolic Process Mitotic Cell Cycle Phase Transition Modification-dependent Protein Catabolic Process Cell Cycle Phase Transition Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Negative Regulation Of Microtubule Depolymerization Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Microtubule Cytoskeleton Organization Spindle Stabilization Positive Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cytoskeleton Organization Regulation Of Microtubule-based Process Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Negative Regulation Of Cell Cycle Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Protein Catabolic Process Regulation Of Cell Cycle Process Positive Regulation Of Cell Cycle Process Cellular Macromolecule Catabolic Process Cellular Protein Localization Cell Cycle Checkpoint Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Regulation Of Organelle Organization Regulation Of Cell Cycle Regulation Of Binding Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Cell Cycle Histone-serine Phosphorylation Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Complex Disassembly Positive Regulation Of Proteolysis Negative Regulation Of Binding Negative Regulation Of Protein Ubiquitination	Regulation Of Microtubule Polymerization Or Depolymerization Mitotic Nuclear Division Negative Regulation Of Microtubule Polymerization Or Depolymerization Cell Division Mitotic Cell Cycle Process Regulation Of Microtubule Cytoskeleton Organization Mitotic Cell Cycle Regulation Of Protein Binding Regulation Of Microtubule-based Process Negative Regulation Of Microtubule Depolymerization Cell Cycle Process Regulation Of Binding Positive Regulation Of Cell Cycle Negative Regulation Of Cytoskeleton Organization Cell Cycle Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cell Cycle Process Microtubule Cytoskeleton Organization Negative Regulation Of Protein Complex Disassembly Positive Regulation Of Microtubule Plus-end Binding Microtubule-based Process Regulation Of Cell Cycle Process Regulation Of Protein Depolymerization Mitotic Cell Cycle Phase Transition Regulation Of Cytoskeleton Organization Cell Cycle Phase Transition Regulation Of Microtubule Polymerization Regulation Of Protein Complex Disassembly Regulation Of Organelle Organization Regulation Of Cell Cycle Histone Phosphorylation Spindle Stabilization Regulation Of Mitotic Cell Cycle Negative Regulation Of Protein Binding Negative Regulation Of Cell Cycle Organelle Organization Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Microtubule Polymerization Histone-serine Phosphorylation Positive Regulation Of Macromolecule Biosynthetic Process Chromosome Organization Negative Regulation Of Binding Positive Regulation Of Gene Expression Microtubule Organizing Center Organization Positive Regulation Of Cellular Biosynthetic Process Protein Localization To Cytoskeleton Regulation Of Protein Complex Assembly
Tagcloud ?			100nm 48h 81m anapc13 calm2 carcinogenic diarrheic drawing exhaustive explanation hn1 malat1 mllt11 molluscs oa okadaic pathologies poisoning positives pttg1 rodents sga shellfish shsy5y ssh subtractive tax1bp1 toxins tumourigenesis
Tagcloud (Difference) ?			100nm 48h 81m anapc13 calm2 carcinogenic diarrheic drawing exhaustive explanation hn1 malat1 mllt11 molluscs oa okadaic pathologies poisoning positives pttg1 rodents sga shellfish shsy5y ssh subtractive tax1bp1 toxins tumourigenesis
Tagcloud (Intersection) ?