AURKB and DCUN1D1

Number of citations of the paper that reports this interaction (PMID 25411243)
0

Data Source:
BioGRID (pull down)

		AURKB	DCUN1D1
Gene Name		aurora kinase B	DCN1, defective in cullin neddylation 1, domain containing 1
Image
Gene Ontology Annotations	Cellular Component	Condensed Chromosome, Centromeric Region Condensed Nuclear Chromosome, Centromeric Region Nucleus Spindle Cytosol Spindle Microtubule Chromocenter Midbody Spindle Pole Centrosome Chromosome Passenger Complex Spindle Midzone	Ubiquitin Ligase Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Binding ATP Binding Histone Serine Kinase Activity Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Mitotic Cell Cycle Negative Regulation Of B Cell Apoptotic Process Protein Phosphorylation Aging Cell Proliferation Attachment Of Spindle Microtubules To Kinetochore Abscission Histone Modification Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Spindle Checkpoint Negative Regulation Of Protein Binding Negative Regulation Of Cytokinesis Positive Regulation Of Cytokinesis Protein Localization To Kinetochore Cellular Response To UV Cleavage Furrow Formation Spindle Stabilization Histone H3-S28 Phosphorylation Protein Autophosphorylation Mitotic Spindle Midzone Assembly Regulation Of Chromosome Segregation	Biological_process
Pathways		Mitotic Prometaphase APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Regulation of mitotic cell cycle Mitotic Anaphase Mitotic Metaphase and Anaphase APC/C-mediated degradation of cell cycle proteins Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		48 interactors: AJUBA ANKZF1 APP BCL2L11 BIRC5 CBX3 CDCA8 CENPA CIB1 CYLD DCUN1D1 DES EVI5 FBXL2 FLOT1 GFAP GNB2L1 GSG2 HIST1H3A HIST2H3C HIST3H3 INCENP KIF20A KLHL13 KLHL21 KLHL9 LATS1 LATS2 MAPRE1 MAPRE2 MAPRE3 NCAPH NDC80 NSUN2 NUF2 PPP2R4 PSMA3 RACGAP1 RASA1 RASSF1 SEPT1 SKA1 SKA3 SUMO1 SUMO2 TACC1 TBL3 TGFBR1	21 interactors: ARRDC3 AURKB CALM1 CAND1 CUL2 CUL3 CUL4A CUL4B DAZAP2 LAPTM5 LZTS2 NEDD4 NEDD8 RHOA RNF11 SMAD2 TP53BP2 TRIM39 TRIM54 UBE2F VPS37B
Entrez ID		9212	54165
HPRD ID		05397	12067
Ensembl ID		ENSG00000178999
Uniprot IDs		Q96GD4	C9JVE2 Q96GG9
PDB IDs		4AF3	3TDU 3TDZ
Enriched GO Terms of Interacting Partners?		Cell Cycle Cell Division Mitotic Cell Cycle Mitotic Cell Cycle Process Cell Cycle Process Mitotic Nuclear Division Organelle Organization Chromosome Segregation Cytokinesis Regulation Of Cell Cycle Regulation Of Microtubule-based Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Microtubule Cytoskeleton Organization Sister Chromatid Segregation Mitotic Spindle Organization Microtubule Cytoskeleton Organization Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Complex Assembly Positive Regulation Of Microtubule Plus-end Binding Regulation Of Cytoskeleton Organization Cellular Localization Protein Complex Localization Regulation Of Organelle Organization Regulation Of Signaling Regulation Of Signal Transduction Regulation Of Protein Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Microtubule Polymerization Or Depolymerization Microtubule-based Process Cellular Process Mitotic Sister Chromatid Segregation Positive Regulation Of Cell Cycle Regulation Of Protein Localization Protein Modification By Small Protein Conjugation Positive Regulation Of Proteolysis Positive Regulation Of Catalytic Activity Regulation Of Catalytic Activity Negative Regulation Of Wnt Signaling Pathway Regulation Of Cell Cycle Process Cytoskeleton Organization Positive Regulation Of Protein Modification Process Regulation Of Protein Kinase Activity G2/M Transition Of Mitotic Cell Cycle Mitotic Cytokinesis Negative Regulation Of Catalytic Activity Spindle Organization Negative Regulation Of Cellular Metabolic Process	Protein Modification By Small Protein Conjugation Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Protein Catabolic Process Regulation Of Cytokinesis Cellular Macromolecule Catabolic Process Regulation Of Cell Cycle Positive Regulation Of Cell Cycle Process Cellular Response To Light Stimulus Cellular Protein Modification Process Regulation Of Cell Cycle Process Positive Regulation Of Cell Cycle Positive Regulation Of Cytokinesis Cellular Response To Radiation Catabolic Process Protein Monoubiquitination Cell Cycle Cleavage Furrow Formation Positive Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Process Positive Regulation Of Cell Cycle Phase Transition Intrinsic Apoptotic Signaling Pathway Proteolysis Cellular Response To UV Protein Neddylation Mitotic Cell Cycle Regulation Of Signal Transduction Response To Radiation Negative Regulation Of Cell Cycle Spindle Midzone Assembly Cellular Protein Metabolic Process Spindle Assembly Regulation Of Cell Division Regulation Of Signaling Developmental Process Viral Process Protein Metabolic Process Cytokinesis Mitotic Nuclear Division Positive Regulation Of Mitotic Cell Cycle Mitotic Spindle Assembly Protein Complex Assembly Cell Cycle Process Positive Regulation Of Cell Division Response To Light Stimulus Spindle Organization Cellular Protein Complex Assembly
Tagcloud ?		allele birc5 cdca8 consortium contribution cpc division european exon familial fifteen fixed genotyped incenp inherited investigates meta modest passenger pivotal rs1675126 rs2071214 snp snps spite sporadic synonymous top variability	achilles adapter adapters amplicons amplifications amplified atlas backgrounds bioinformatics datasets driver druggable emphasis fgfr frs2 gistic2 grb7 hedgehog kras narrowed nsd3 pik3ca projects putative referencing shrna spanning tailoring tcga
Tagcloud (Difference) ?		allele birc5 cdca8 consortium contribution cpc division european exon familial fifteen fixed genotyped incenp inherited investigates meta modest passenger pivotal rs1675126 rs2071214 snp snps spite sporadic synonymous top variability	achilles adapter adapters amplicons amplifications amplified atlas backgrounds bioinformatics datasets driver druggable emphasis fgfr frs2 gistic2 grb7 hedgehog kras narrowed nsd3 pik3ca projects putative referencing shrna spanning tailoring tcga
Tagcloud (Intersection) ?