MAPRE3 and CRTAC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MAPRE3	CRTAC1
Description		microtubule associated protein RP/EB family member 3	cartilage acidic protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Cytoskeleton Microtubule Cytoplasmic Microtubule Microtubule Cytoskeleton Midbody Microtubule Plus-end Perinuclear Region Of Cytoplasm Spindle Midzone Neuron To Neuron Synapse Mitotic Spindle Astral Microtubule End Microtubule End	Extracellular Region Postsynaptic Density Growth Cone Extracellular Exosome Glutamatergic Synapse
	Molecular Function	Protein Binding Microtubule Binding Identical Protein Binding Protein Serine/threonine Kinase Activator Activity Microtubule Plus-end Binding Protein Serine/threonine Kinase Binding	Calcium Ion Binding Protein Binding
	Biological Process	Intracellular Protein Localization Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule Polymerization Protein Localization To Microtubule Positive Regulation Of DNA-templated Transcription Behavioral Response To Cocaine Spindle Assembly Cell Division Positive Regulation Of Dendritic Spine Morphogenesis	Axonal Fasciculation Olfactory Bulb Development Regulation Of Synapse Assembly
Pathways
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Estimated glomerular filtration rate in non-diabetics ( 31451708) Left–right brain asymmetry ( 33723403) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Post bronchodilator FEV1/FVC ratio ( 26634245) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Adult body size ( 32376654) Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 30072576) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Evening vs. morning chronotype (self-assessed) ( 32579418) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Hand grip strength ( 29691431) HDL cholesterol levels ( 32203549) Lung cancer in never smokers ( 28604730) Metabolic syndrome ( 31589552 20694148) Multisite chronic pain ( 33830993) Severe insulin-resistant type 2 diabetes ( 34737425) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Triglyceride levels ( 32203549) Walking pace ( 33128006)
Interacting Genes		56 interacting genes: ANKRD1 APC2 AURKA AURKB C20orf202 CCSER1 CHRDL2 CLASP1 CRTAC1 DCTN2 DDIT4L DOK4 EIF4E2 FAM161B FOXD4L1 FOXD4L4 FXR2 GTF2F2 GTSE1 HROB IKZF1 JUN KIF19 KLHDC7B KNSTRN LAP3 LHX4 LMO2 MAPRE2 MARCHF7 MEOX2 MRPL12 PDE4DIP PICK1 POU4F1 PSMA1 PSMB1 PSRC1 RAB1A REL SDCBP SIAH1 SLAIN1 SPDYE2 SPDYE2B SPMIP10 SPMIP2 TLE5 TRAIP TRIM14 TXN2 YAF2 ZC2HC1A ZC2HC1C ZNF526 ZNF547	5 interacting genes: AQP1 CRYAA DSCAM MAPRE3 MORN4
Entrez ID		22924	55118
HPRD ID		16156	10447
Ensembl ID		ENSG00000084764	ENSG00000095713
Uniprot IDs		Q9UPY8	Q9NQ79
PDB IDs		1WYO 3CO1 3JAK 3JAL 3JAR 3TQ7 7SJ9
Enriched GO Terms of Interacting Partners?		Regulation Of Microtubule Polymerization Or Depolymerization Microtubule-based Process Microtubule Cytoskeleton Organization Spindle Organization Regulation Of Microtubule Cytoskeleton Organization Cytoplasmic Microtubule Microtubule Plus-end Microtubule Cytoskeleton Regulation Of Microtubule-based Process Positive Regulation Of Microtubule Polymerization Cytoskeleton Spindle Microtubule Cytoskeleton Organization Microtubule Microtubule Organizing Center Plasma Membrane Bounded Cell Projection Organization Microtubule Plus-end Binding Cytoplasmic Microtubule Organization Regulation Of Microtubule Polymerization Spindle Midzone Protein Binding Cell Projection Organization Chromosome Passenger Complex Positive Regulation Of Protein Polymerization Microtubule Binding Kinetochore Mitotic Spindle Organization Spindle Assembly Positive Regulation Of Supramolecular Fiber Organization Regulation Of Microtubule Depolymerization Regulation Of Supramolecular Fiber Organization Regulation Of Cytoskeleton Organization Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Epithelial Cell Migration Cilium Disassembly Protein Localization To Cytoskeleton Astral Microtubule Organization Beta-catenin Destruction Complex Regulation Of Signal Transduction By P53 Class Mediator Microtubule Cytoskeleton Organization Involved In Mitosis Negative Regulation Of Interferon-beta Production Positive Regulation Of Organelle Organization Regulation Of Organelle Organization Regulation Of Epithelial Cell Migration	Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Eye Morphogenesis Sensory Organ Morphogenesis Nitric Oxide Transmembrane Transporter Activity Metanephric Proximal Convoluted Tubule Segment 2 Development Response To Hydrogen Peroxide Metanephric Glomerulus Vasculature Development Positive Regulation Of Saliva Secretion Response To UV Cellular Response To Mercury Ion Hydrogen Peroxide Channel Activity Potassium Ion Transmembrane Transporter Activity Response To Reactive Oxygen Species Glycerol Transmembrane Transporter Activity Corticotropin Secretion Positive Regulation Of Cell Growth Post-embryonic Retina Morphogenesis In Camera-type Eye Netrin Receptor Binding Mitotic Spindle Astral Microtubule End Nitric Oxide Transport Establishment Or Maintenance Of Actin Cytoskeleton Polarity Cerebrospinal Fluid Secretion Renal Water Absorption Carbon Dioxide Transmembrane Transporter Activity Glomerulus Vasculature Development Regulation Of Anatomical Structure Morphogenesis Water Transmembrane Transporter Activity Transepithelial Water Transport Hydrogen Peroxide Transmembrane Transport Intracellularly CGMP-activated Cation Channel Activity Carbon Dioxide Transmembrane Transport Lipid Digestion Response To Wounding Pancreatic Juice Secretion Positive Regulation Of Axon Extension Involved In Axon Guidance Positive Regulation Of Neurogenesis Microtubule End Ankyrin-1 Complex Glycerol Transmembrane Transport Intracellular Water Homeostasis Lens Fiber Cell Morphogenesis Positive Regulation Of Growth Renal Water Transport Regulation Of Saliva Secretion Neuron To Neuron Synapse Actin-based Cell Projection Positive Regulation Of Nervous System Development Ammonium Channel Activity Polyol Transmembrane Transport
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