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FRS3
Gene Name
fibroblast growth factor receptor substrate 3
Image
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Molecular Function
Fibroblast Growth Factor Receptor Binding
Insulin Receptor Binding
Protein Binding
Biological Process
Signal Transduction
Fibroblast Growth Factor Receptor Signaling Pathway
Pathways
Signaling by FGFR in disease
FRS2-mediated cascade
Downstream signaling of activated FGFR
Signaling by FGFR
Drugs
Diseases
GWAS
Protein-protein Interactions
20 interactors:
ADAMTSL4
AES
BMPR2
FGFR1
GATA1
GRB2
KARS
MAPK1
NOTCH2NL
NTRK1
NTRK2
PLSCR1
PRKCI
PTPN11
RFX6
RND1
SPERT
SPRY2
TCF4
TRIP6
Entrez ID
10817
HPRD ID
06373
Ensembl ID
ENSG00000137218
Uniprot IDs
O43559
PDB IDs
2KUP
2KUQ
2YS5
2YT2
Enriched GO Terms of Interacting Partners
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Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Anatomical Structure Morphogenesis
Regulation Of Signaling
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Cell Differentiation
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Signal Transduction
Regulation Of Signal Transduction
Cell Development
Response To External Stimulus
Organ Development
Positive Regulation Of Protein Phosphorylation
Response To Organic Substance
Multicellular Organismal Development
Positive Regulation Of Cellular Metabolic Process
Generation Of Neurons
Positive Regulation Of Intracellular Signal Transduction
System Development
Positive Regulation Of Neuron Differentiation
Neurogenesis
Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Phosphorylation
Positive Regulation Of Protein Metabolic Process
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Positive Regulation Of Protein Modification Process
Regulation Of Phosphorylation
Cellular Response To Fibroblast Growth Factor Stimulus
Regulation Of MAPK Cascade
Response To Fibroblast Growth Factor
Neuron Development
Developmental Process
Intracellular Signal Transduction
Axon Guidance
Organ Morphogenesis
Positive Regulation Of Neurogenesis
Cell Surface Receptor Signaling Pathway
Signaling
Cellular Response To Insulin Stimulus
Regulation Of Apoptotic Process
Regulation Of Phosphorus Metabolic Process
Regulation Of Cell Proliferation
Positive Regulation Of Neuron Projection Development
Cell Communication
Regulation Of Protein Phosphorylation
Cell Morphogenesis Involved In Differentiation
Epithelium Development
Tagcloud
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2yf
4yf
adapters
alleviated
anophthalmia
coordinated
ectodermal
embryogenesis
eye
fgf
fgfr
laevis
maternally
microphthalmia
mo
morphants
morpholino
oligonucleotide
pax6
pi3
placode
rescue
served
shp2
vertebrate
xenopus
xfrs3
zygotically