Wiki-Pi
About
Search
People
Updates
Search
FRS3 and PLSCR1
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid)
FRS3
PLSCR1
Description
fibroblast growth factor receptor substrate 3
phospholipid scramblase 1
Image
GO Annotations
Cellular Component
Cytoplasm
Plasma Membrane
Membrane
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Golgi Apparatus
Cytosol
Plasma Membrane
Membrane
Membrane Raft
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Molecular Function
Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity
Fibroblast Growth Factor Receptor Binding
Protein Binding
Identical Protein Binding
Magnesium Ion Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Virus Receptor Activity
DNA Binding
Nuclease Activity
Epidermal Growth Factor Receptor Binding
Calcium Ion Binding
Protein Binding
Zinc Ion Binding
Hydrolase Activity
SH3 Domain Binding
Phospholipid Scramblase Activity
Enzyme Binding
Lead Ion Binding
CD4 Receptor Binding
Mercury Ion Binding
Biological Process
Signal Transduction
Fibroblast Growth Factor Receptor Signaling Pathway
Phosphatidylserine Biosynthetic Process
Lipid Transport
Apoptotic Process
Acute-phase Response
Response To Lead Ion
Positive Regulation Of Gene Expression
Plasma Membrane Phospholipid Scrambling
Platelet Activation
Regulation Of Mast Cell Activation
Response To Interferon-beta
Negative Regulation Of Viral Genome Replication
Positive Regulation Of Innate Immune Response
Positive Regulation Of Transcription By RNA Polymerase II
Symbiont Entry Into Host Cell
Negative Regulation Of Phagocytosis
Defense Response To Virus
Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway
Phosphatidylserine Exposure On Apoptotic Cell Surface
Positive Regulation Of Chromosome Separation
Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity
Pathways
FRS-mediated FGFR1 signaling
FRS-mediated FGFR2 signaling
FRS-mediated FGFR3 signaling
FRS-mediated FGFR4 signaling
RAF/MAP kinase cascade
Activated NTRK2 signals through FRS2 and FRS3
RND2 GTPase cycle
RND1 GTPase cycle
Signaling by ALK fusions and activated point mutants
Drugs
Diseases
GWAS
Menarche (age at onset) (
25231870
)
Gut microbiota (beta diversity) (
27723756
)
Interacting Genes
112 interacting genes:
ACTMAP
ADAMTSL4
ANAPC11
ANKRD55
ATP23
BLZF1
BMPR2
C22orf39
CATSPER1
CBY2
CCDC33
CCN3
CDPF1
CFAP68
COL8A1
COPS3
CREB5
CYSRT1
DCDC2B
DDX5
DMRT3
DPEP2NB
ECM1
ESM1
FGFR1
GATA1
GPRIN2
GRB14
GRB2
HOXA1
HOXD12
ID2
ID3
IKZF3
INCA1
ISY1-RAB43
KARS1
KATNBL1
KCNJ5-AS1
KIAA0408
KPRP
KRT31
KRT33B
KRT34
KRT35
KRT76
KRTAP1-1
KRTAP10-8
KRTAP11-1
KRTAP3-1
KRTAP3-2
KRTAP6-2
LINGO1
LRRC18
MAPK1
MATK
MBD3L1
MIIP
NADSYN1
NBPF19
NOTCH2NLA
NTRK1
NTRK2
NUMB
PCSK5
PDLIM7
PIH1D2
PLB1
PLLP
PLSCR1
POF1B
PRDM6
PRKCI
PTPN11
RFX6
RIMBP3C
RND1
SAXO4
SCNM1
SH2B1
SHANK3
SLAIN1
SLC67A1-AS
SOCS6
SPATA12
SPRY2
STH
STK16
TCF4
TCP10L
TGM7
TLE5
TNS1
TRAF4
TRIP6
TSC1
TSGA10IP
TSPAN4
UNKL
VASP
VGLL3
WDR83
WWOX
YPEL3
ZMIZ2
ZNF124
ZNF417
ZNF438
ZNF446
ZNF552
ZNF69
ZSCAN30
132 interacting genes:
ABL1
ADAMTSL4
ADCY7
ANXA11
APP
ARNT2
ATG12
ATN1
BACE1
BCL6B
C10orf62
CATSPER1
CCDC33
CCER1
CDC42EP1
CHRD
CNTFR
CPSF6
CRK
CRKL
CRY1
CTBP1-DT
CTSZ
DAZAP2
DDIAS
DEF6
DEPP1
DHRS1
DLK2
DMRT3
DOCK2
DTX2
EFEMP2
EGFR
ENKD1
EP300
ESR2
EWSR1
EXD3
FAM107A
FBLN1
FBXL18
FRAT1
FRS3
GDPD5
GLRX3
GNAI2
GPRIN2
HEY2
HOXA1
HOXA9
HOXB6
HRG
ILF3
INTS11
IP6K2
IQCN
KIF1A
KRTAP10-11
KRTAP10-3
KRTAP10-9
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP5-6
KRTAP9-2
LASP1
LCE2D
LCE3C
LCE4A
LGALS9C
LINC00663
LINC01547
LONRF1
MAPK6
MDK
MED15
MGAT5B
MVP
NECAP2
NEU4
NOC4L
NPDC1
NR0B2
NTN4
OGDH
P2RY6
PCED1A
PGLS
PHLDA1
PITX1
PKD2
PLSCR3
PLSCR4
PML
PPDPF
PRKCD
PRR13
RAMAC
RASD1
RBL1
RERE
RGS3
RXRB
SCNM1
SF1
SHC1
SLC25A6
SLC35A2
SLPI
SMARCC1
SMCP
SPATA8
SPG7
SPRY2
SRC
STK16
TFG
THBS1
TRAF4
TRIM42
VASP
VPS37C
VSIR
YIPF3
ZBTB16
ZNF417
ZNF581
ZNF587
ZNF638
ZNF688
ZNF764
Entrez ID
10817
5359
HPRD ID
06373
08855
Ensembl ID
ENSG00000137218
ENSG00000188313
Uniprot IDs
A0A140VJJ7
O43559
C9J7K9
O15162
PDB IDs
2KUP
2KUQ
2YS5
2YT2
1Y2A
Enriched GO Terms of Interacting Partners
?
Keratin Filament
Intermediate Filament
Protein Binding
Outer Ear Morphogenesis
Structural Constituent Of Skin Epidermis
Regulation Of Transcription By RNA Polymerase II
Regulation Of Ossification
Cellular Developmental Process
Anatomical Structure Morphogenesis
Structural Molecule Activity
Intermediate Filament Organization
Developmental Process
Anatomical Structure Formation Involved In Morphogenesis
Response To Growth Factor
Neurotrophin Receptor Activity
Neurotrophin Binding
Negative Regulation Of Chondrocyte Proliferation
Myelination
Intermediate Filament Cytoskeleton Organization
Supramolecular Fiber Organization
Intermediate Filament-based Process
Cell Differentiation
Axon Ensheathment
Cellular Response To Growth Factor Stimulus
Enzyme Binding
Ephrin Receptor Binding
Protein Binding
Positive Regulation Of ERK1 And ERK2 Cascade
Regulation Of Cell-substrate Adhesion
Cellular Response To Transforming Growth Factor Beta Stimulus
Keratin Filament
Cellular Response To Growth Factor Stimulus
Regulation Of ERK1 And ERK2 Cascade
Response To Transforming Growth Factor Beta
Intermediate Filament
Response To Growth Factor
Regulation Of Cell Adhesion
Positive Regulation Of MAPK Cascade
Helper T Cell Diapedesis
Shc-EGFR Complex
Positive Regulation Of Cell-substrate Adhesion
Regulation Of Superoxide Metabolic Process
Negative Regulation Of Long-term Synaptic Potentiation
Regulation Of Substrate Adhesion-dependent Cell Spreading
Negative Regulation Of Cell Adhesion
Positive Regulation Of Cell Adhesion
Response To Lipid
Hair Cycle
Apoptotic Process
Regulation Of Focal Adhesion Assembly
Regulation Of MAPK Cascade
Cerebellar Neuron Development
Regulation Of Apoptotic Process
Protein Tyrosine Kinase Activator Activity
Cellular Response To Lipid
Morphogenesis Of A Branching Structure
ERBB Signaling Pathway
Regulation Of DNA-templated Transcription
Regulation Of Cell-substrate Junction Organization
Gland Development
Regulation Of RNA Biosynthetic Process
Programmed Cell Death
Cell Death
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Non-membrane Spanning Protein Tyrosine Kinase Activity
Epidermal Growth Factor Binding
System Development
Regulation Of Cell Population Proliferation
Cellular Response To Oxygen-containing Compound
Positive Regulation Of Cell Migration
Regulation Of Programmed Cell Death
Regulation Of Cell-matrix Adhesion
Positive Regulation Of Superoxide Anion Generation
Central Nervous System Neuron Development
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?