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FRS3 and TSPAN4
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
FRS3
TSPAN4
Description
fibroblast growth factor receptor substrate 3
tetraspanin 4
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Plasma Membrane
Membrane
Plasma Membrane
Focal Adhesion
Membrane
Vesicle
Molecular Function
Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity
Fibroblast Growth Factor Receptor Binding
Protein Binding
Identical Protein Binding
Antigen Binding
Integrin Binding
Protein Binding
Biological Process
Signal Transduction
Fibroblast Growth Factor Receptor Signaling Pathway
Protein-containing Complex Assembly
Pathways
FRS-mediated FGFR1 signaling
FRS-mediated FGFR2 signaling
FRS-mediated FGFR3 signaling
FRS-mediated FGFR4 signaling
RAF/MAP kinase cascade
Activated NTRK2 signals through FRS2 and FRS3
RND2 GTPase cycle
RND1 GTPase cycle
Signaling by ALK fusions and activated point mutants
Drugs
Diseases
GWAS
Menarche (age at onset) (
25231870
)
Falling risk (
32999390
)
Interacting Genes
112 interacting genes:
ACTMAP
ADAMTSL4
ANAPC11
ANKRD55
ATP23
BLZF1
BMPR2
C22orf39
CATSPER1
CBY2
CCDC33
CCN3
CDPF1
CFAP68
COL8A1
COPS3
CREB5
CYSRT1
DCDC2B
DDX5
DMRT3
DPEP2NB
ECM1
ESM1
FGFR1
GATA1
GPRIN2
GRB14
GRB2
HOXA1
HOXD12
ID2
ID3
IKZF3
INCA1
ISY1-RAB43
KARS1
KATNBL1
KCNJ5-AS1
KIAA0408
KPRP
KRT31
KRT33B
KRT34
KRT35
KRT76
KRTAP1-1
KRTAP10-8
KRTAP11-1
KRTAP3-1
KRTAP3-2
KRTAP6-2
LINGO1
LRRC18
MAPK1
MATK
MBD3L1
MIIP
NADSYN1
NBPF19
NOTCH2NLA
NTRK1
NTRK2
NUMB
PCSK5
PDLIM7
PIH1D2
PLB1
PLLP
PLSCR1
POF1B
PRDM6
PRKCI
PTPN11
RFX6
RIMBP3C
RND1
SAXO4
SCNM1
SH2B1
SHANK3
SLAIN1
SLC67A1-AS
SOCS6
SPATA12
SPRY2
STH
STK16
TCF4
TCP10L
TGM7
TLE5
TNS1
TRAF4
TRIP6
TSC1
TSGA10IP
TSPAN4
UNKL
VASP
VGLL3
WDR83
WWOX
YPEL3
ZMIZ2
ZNF124
ZNF417
ZNF438
ZNF446
ZNF552
ZNF69
ZSCAN30
49 interacting genes:
CATSPER1
CD46
CD81
CD9
CHRD
CLDN11
CLEC2D
CREB3
CREB5
CYSRT1
EVA1A
FCHO1
FRS3
GNE
GRN
GUCD1
HOXA1
ITGA3
ITGA6
ITGB1
KRTAP10-1
KRTAP10-8
KRTAP4-11
KRTAP4-5
KRTAP6-2
KRTAP9-2
KRTAP9-3
LCE1A
LCE2B
LCE2D
LCE3A
LCE3C
LCE3D
LCE4A
LRRC25
LTB4R2
MDFI
MGAT5B
MKRN3
NBPF19
NOTCH2NLA
NR4A3
OTX1
PHLDA1
PLSCR4
SGPL1
TEKT4
TMEM106A
VGLL3
Entrez ID
10817
7106
HPRD ID
06373
04033
Ensembl ID
ENSG00000137218
ENSG00000214063
Uniprot IDs
A0A140VJJ7
O43559
A8MVV6
O14817
PDB IDs
2KUP
2KUQ
2YS5
2YT2
Enriched GO Terms of Interacting Partners
?
Keratin Filament
Intermediate Filament
Protein Binding
Outer Ear Morphogenesis
Structural Constituent Of Skin Epidermis
Regulation Of Transcription By RNA Polymerase II
Regulation Of Ossification
Cellular Developmental Process
Anatomical Structure Morphogenesis
Structural Molecule Activity
Intermediate Filament Organization
Developmental Process
Anatomical Structure Formation Involved In Morphogenesis
Response To Growth Factor
Neurotrophin Receptor Activity
Neurotrophin Binding
Negative Regulation Of Chondrocyte Proliferation
Myelination
Intermediate Filament Cytoskeleton Organization
Supramolecular Fiber Organization
Intermediate Filament-based Process
Cell Differentiation
Axon Ensheathment
Cellular Response To Growth Factor Stimulus
Keratinization
Epidermis Development
Keratin Filament
Intermediate Filament
Integrin Alpha6-beta1 Complex
Integrin Alpha3-beta1 Complex
Myoblast Fusion Involved In Skeletal Muscle Regeneration
Myoblast Fusion
Integrin Complex
Cellular Response To Low-density Lipoprotein Particle Stimulus
Cellular Response To Lipoprotein Particle Stimulus
Cell-cell Fusion
Syncytium Formation
Syncytium Formation By Plasma Membrane Fusion
Cerebellar Climbing Fiber To Purkinje Cell Synapse
Identical Protein Binding
CAMP Response Element Binding
Regulation Of Cell Motility
Hair Cycle
Regulation Of Locomotion
Integrin Binding
Mesodermal Cell Differentiation
Tissue Development
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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