SYN1 and SYN3

Number of citations of the paper that reports this interaction (PMID 10358015)
11

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		SYN1	SYN3
Gene Name		synapsin I	synapsin III
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Cytosol Synaptic Vesicle Cell Junction Dendrite	Synaptic Vesicle Cell Junction Synaptic Vesicle Membrane
	Molecular Function	Actin Binding Catalytic Activity Transporter Activity Protein Binding ATP Binding Protein Kinase Binding Calcium-dependent Protein Binding	Catalytic Activity ATP Binding
	Biological Process	Synaptic Transmission Neurotransmitter Secretion Metabolic Process Regulation Of Neurotransmitter Secretion Regulation Of Synaptic Vesicle Exocytosis	Neurotransmitter Secretion Metabolic Process Regulation Of Synaptic Transmission, GABAergic
Pathways		Dopamine Neurotransmitter Release Cycle Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle Transmission across Chemical Synapses	Dopamine Neurotransmitter Release Cycle Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle Transmission across Chemical Synapses
Drugs
Diseases
GWAS			Age-related macular degeneration ( 20385819) Height ( 21998595 20881960)
Protein-Protein Interactions		30 interactors: AMPH BIN1 BLM CAMK1 CAMK2G CDK5 CRK ERG GRB2 ITSN2 KAT5 MAPK3 NOS1 NOS1AP PAK1 PAK2 PAK3 PFN2 PIK3R1 PLCG1 PRKACA RASA1 S100A1 SH3GL2 SNCA SPTAN1 SRC SYN2 SYN3 VIM	3 interactors: NOS1AP SYN1 SYN2
Entrez ID		6853	8224
HPRD ID		02433	04083
Ensembl ID		ENSG00000008056	ENSG00000185666
Uniprot IDs		P17600	O14994 Q17R54 Q59EX7
PDB IDs			2P0A
Enriched GO Terms of Interacting Partners?		Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Modification Process Positive Regulation Of Catalytic Activity Endocytosis Positive Regulation Of Metabolic Process Regulation Of Cellular Component Organization Axon Guidance Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Catalytic Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Metabolic Process Chemotaxis Regulation Of Kinase Activity Positive Regulation Of Protein Kinase Activity Regulation Of Phosphorylation Positive Regulation Of Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Axonogenesis Positive Regulation Of Protein Phosphorylation Positive Regulation Of Transport Regulation Of Protein Kinase Activity Positive Regulation Of Transferase Activity Immune Response-activating Cell Surface Receptor Signaling Pathway Axon Development Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Neuron Differentiation Locomotion Cell Differentiation Positive Regulation Of Cellular Metabolic Process Signaling Regulation Of Protein Phosphorylation Neuron Projection Morphogenesis Regulation Of Signaling Nervous System Development Neurotrophin TRK Receptor Signaling Pathway Cell Communication Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Phosphorylation Neurotrophin Signaling Pathway Regulation Of Cytoskeleton Organization Regulation Of Organelle Organization T Cell Costimulation Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Morphogenesis Involved In Differentiation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Actin Filament-based Process Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Protein Metabolic Process	Neurotransmitter Secretion Regulation Of Neurotransmitter Levels Positive Regulation Of Nitric Oxide Mediated Signal Transduction Neurotransmitter Transport Positive Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Generation Of L-type Calcium Current Positive Regulation Of Delayed Rectifier Potassium Channel Activity Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Delayed Rectifier Potassium Channel Activity Regulation Of Heart Rate By Chemical Signal Secretion By Cell Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Synaptic Transmission Secretion Positive Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Voltage-gated Calcium Channel Activity Regulation Of Membrane Repolarization Positive Regulation Of Monooxygenase Activity Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Potassium Ion Transport Positive Regulation Of Cation Channel Activity Regulation Of Synaptic Vesicle Exocytosis Cell-cell Signaling Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Oxidoreductase Activity Regulation Of Potassium Ion Transmembrane Transport Regulation Of Synaptic Vesicle Transport Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Transporter Activity Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Calcium Ion Transmembrane Transport Regulation Of Potassium Ion Transport Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Neurotransmitter Secretion Regulation Of Heart Rate Regulation Of Oxidoreductase Activity Positive Regulation Of Ion Transmembrane Transport Regulation Of Cation Channel Activity Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Exocytosis Regulation Of Reactive Oxygen Species Metabolic Process Establishment Of Localization In Cell
Tagcloud ?		anthropometry bf bifidobacterium bifidogenic breastfed breastfeeding carbohydrates closer colonized digestive faecal fermentable formula formulas infant inulin microbiota nct00808756 newborns oligofructose orafti prebiotic softer sterile stool stools supplemented synergy1 try
Tagcloud (Difference) ?		anthropometry bf bifidobacterium bifidogenic breastfed breastfeeding carbohydrates closer colonized digestive faecal fermentable formula formulas infant inulin microbiota nct00808756 newborns oligofructose orafti prebiotic softer sterile stool stools supplemented synergy1 try
Tagcloud (Intersection) ?