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KCTD6 and ACTN1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
KCTD6
ACTN1
Gene Name
potassium channel tetramerization domain containing 6
actinin, alpha 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Stress Fiber
Ruffle
Extracellular Region
Extracellular Space
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Fascia Adherens
Focal Adhesion
Z Disc
Cortical Actin Cytoskeleton
Platelet Alpha Granule Lumen
Pseudopodium
Cell Projection
Dendritic Spine
Extracellular Vesicular Exosome
Molecular Function
Ankyrin Binding
Double-stranded RNA Binding
Integrin Binding
Calcium Ion Binding
Protein Binding
Vinculin Binding
Protein Domain Specific Binding
Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
Ion Channel Binding
Actin Filament Binding
Biological Process
Protein Homooligomerization
Platelet Degranulation
Blood Coagulation
Platelet Activation
Extracellular Matrix Organization
Cell Junction Assembly
Regulation Of Apoptotic Process
Focal Adhesion Assembly
Actin Filament Bundle Assembly
Negative Regulation Of Cellular Component Movement
Actin Crosslink Formation
Regulation Of Nucleic Acid-templated Transcription
Pathways
Cell junction organization
Syndecan interactions
Response to elevated platelet cytosolic Ca2+
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Nephrin interactions
Platelet degranulation
Non-integrin membrane-ECM interactions
Platelet activation, signaling and aggregation
Cell-extracellular matrix interactions
Drugs
Diseases
GWAS
Prostate cancer (
23535732
)
Smoking behavior (
19247474
)
Protein-Protein Interactions
19 interactors:
ACTN1
ACTN3
ANK1
C8orf33
CDC23
CTNND1
CUL3
EHHADH
FAM124B
GOLGA8EP
GOLGA8F
GRB7
GSDMD
LNX1
PPIG
PRPF31
SDCBP
UBC
ZCCHC10
70 interactors:
ACTN3
ADORA2A
APC
ATXN2
ATXN7
CACNA1A
CAMK2A
CDK5
CDK5R1
CDK5R2
CLIC5
COIL
COL17A1
CSRP1
CSRP3
CTNNA1
EPM2AIP1
ERBB2IP
FBP1
FXN
GFI1B
GIPC1
GIT2
GRIA4
GRIN2A
GTF2H1
ITGB1
KAT2B
KCTD6
KPNA2
LPP
MAGEA11
MAP2
MAP3K1
MED14
MICALL2
MYOT
MYOZ1
MYOZ2
MYOZ3
NEBL
NR1H3
NUMBL
OAS1
PALLD
PDHX
PDLIM1
PDLIM5
PIAS4
PKD1
PKN1
PLD2
PSEN1
PSMA1
PTK2
PTPN1
PTPN6
PYGB
RAVER1
RPS27
SLC2A4
SORBS2
SPERT
SRC
SSX2IP
TES
TTN
VCL
XRCC4
ZYX
Entrez ID
200845
87
HPRD ID
13769
00020
Ensembl ID
ENSG00000168301
ENSG00000072110
Uniprot IDs
Q8NC69
P12814
PDB IDs
2EYI
2EYN
Enriched GO Terms of Interacting Partners
?
Cellular Component Assembly
Adherens Junction Organization
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Negative Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Cellular Protein Catabolic Process
Mitotic Metaphase Plate Congression
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Focal Adhesion Assembly
Metaphase Plate Congression
Modification-dependent Protein Catabolic Process
Negative Regulation Of Wnt Signaling Pathway
Cell Junction Assembly
Proteolysis Involved In Cellular Protein Catabolic Process
Cell-cell Junction Organization
Cellular Protein Catabolic Process
Positive Regulation Of Protein Catabolic Process
Regulation Of Mitotic Cell Cycle Phase Transition
Protein Ubiquitination
Regulation Of Canonical Wnt Signaling Pathway
Establishment Of Chromosome Localization
Regulation Of Cell Cycle Phase Transition
Adherens Junction Assembly
Protein Modification By Small Protein Conjugation
Protein Catabolic Process
Regulation Of Mitotic Sister Chromatid Separation
Regulation Of Mitotic Metaphase/anaphase Transition
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Actin Filament-based Process
Cell-substrate Junction Assembly
Proteasomal Protein Catabolic Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Establishment Of Localization In Cell
Positive Regulation Of Proteolysis
Actin Filament Bundle Assembly
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Transferase Activity
Negative Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Wnt Signaling Pathway
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Mitotic Sister Chromatid Segregation
Negative Regulation Of Cellular Protein Metabolic Process
Regulation Of Chromosome Segregation
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Cytoskeleton Organization
Cell Adhesion
Cellular Component Assembly
Organelle Organization
Cell Development
Regulation Of Protein Kinase Activity
Actin Filament-based Process
Regulation Of Kinase Activity
Regulation Of Cellular Protein Metabolic Process
Actin Cytoskeleton Organization
Cell Morphogenesis Involved In Differentiation
Regulation Of Protein Metabolic Process
Cell-substrate Adhesion
Anatomical Structure Morphogenesis
Neurogenesis
Regulation Of Phosphorus Metabolic Process
Cell Differentiation
Generation Of Neurons
Cell Morphogenesis
Regulation Of Protein Phosphorylation
Response To Stress
Actomyosin Structure Organization
Neuron Development
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Catalytic Activity
Central Nervous System Development
Positive Regulation Of Transferase Activity
Regulation Of Signaling
Response To Stimulus
Response To Wounding
Regulation Of Phosphorylation
Cell-cell Junction Organization
Regulation Of Cell Projection Organization
Nervous System Development
Anatomical Structure Formation Involved In Morphogenesis
Single Organismal Cell-cell Adhesion
Adherens Junction Organization
Neuron Projection Development
Neuron Differentiation
Anatomical Structure Development
Blood Coagulation
Cell Surface Receptor Signaling Pathway
Cell Projection Organization
Hemostasis
Cell-matrix Adhesion
Apical Junction Assembly
Cell Morphogenesis Involved In Neuron Differentiation
Regulation Of Signal Transduction
Regulation Of Cell Death
Regulation Of Neuron Projection Development
Tagcloud
?
b5
bcat1
carbamoyl
ctnnd1
egfr1
eph
filamin
flna
genego
i2d
interactors
interologous
metadherin
mtdh
nucleolin
pathwaycommons
plec
plectin
pycard
pyd
rpkm
s100a2
serpinb5
signalings
stratifin
subpathway
sum149
sum190
tfrc
Tagcloud (Difference)
?
b5
bcat1
carbamoyl
ctnnd1
egfr1
eph
filamin
flna
genego
i2d
interactors
interologous
metadherin
mtdh
nucleolin
pathwaycommons
plec
plectin
pycard
pyd
rpkm
s100a2
serpinb5
signalings
stratifin
subpathway
sum149
sum190
tfrc
Tagcloud (Intersection)
?