KCTD6 and ANK1

Number of citations of the paper that reports this interaction (PMID 22573887)
7

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		KCTD6	ANK1
Gene Name		potassium channel tetramerization domain containing 6	ankyrin 1, erythrocytic
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Cytosol Cytoskeleton Plasma Membrane Spectrin-associated Cytoskeleton Basolateral Plasma Membrane Sarcoplasmic Reticulum Z Disc Axolemma Cortical Cytoskeleton M Band Sarcolemma Postsynaptic Membrane
	Molecular Function	Ankyrin Binding	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Adaptor Activity Enzyme Binding Spectrin Binding ATPase Binding
	Biological Process	Protein Homooligomerization	Porphyrin-containing Compound Biosynthetic Process Exocytosis ER To Golgi Vesicle-mediated Transport Cytoskeleton Organization Signal Transduction Axon Guidance Positive Regulation Of Organelle Organization Monovalent Inorganic Cation Transport Maintenance Of Epithelial Cell Apical/basal Polarity Erythrocyte Development Iron Ion Homeostasis Protein Targeting To Plasma Membrane
Pathways			Interaction between L1 and Ankyrins CHL1 interactions Axon guidance Neurofascin interactions NrCAM interactions L1CAM interactions
Drugs
Diseases
GWAS			Glycated hemoglobin levels ( 20858683) Pulmonary function decline ( 22424883) Type 2 diabetes ( 22456796)
Protein-Protein Interactions		19 interactors: ACTN1 ACTN3 ANK1 C8orf33 CDC23 CTNND1 CUL3 EHHADH FAM124B GOLGA8EP GOLGA8F GRB7 GSDMD LNX1 PPIG PRPF31 SDCBP UBC ZCCHC10	18 interactors: BLOC1S6 CD44 EPB42 ITPR3 KCTD6 L1CAM NBPF3 NEDD8 NFASC OBSCN RHAG SLC4A1 SLC4A3 SPTA1 SPTAN1 SPTB TIAM1 TTN
Entrez ID		200845	286
HPRD ID		13769	01693
Ensembl ID		ENSG00000168301	ENSG00000029534
Uniprot IDs		Q8NC69	B3KX39 P16157
PDB IDs			1N11 2YQF 2YVI 3F59 3KBT 3KBU 3UD1 3UD2
Enriched GO Terms of Interacting Partners?		Cellular Component Assembly Adherens Junction Organization Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Cellular Protein Catabolic Process Mitotic Metaphase Plate Congression Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Focal Adhesion Assembly Metaphase Plate Congression Modification-dependent Protein Catabolic Process Negative Regulation Of Wnt Signaling Pathway Cell Junction Assembly Proteolysis Involved In Cellular Protein Catabolic Process Cell-cell Junction Organization Cellular Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Protein Ubiquitination Regulation Of Canonical Wnt Signaling Pathway Establishment Of Chromosome Localization Regulation Of Cell Cycle Phase Transition Adherens Junction Assembly Protein Modification By Small Protein Conjugation Protein Catabolic Process Regulation Of Mitotic Sister Chromatid Separation Regulation Of Mitotic Metaphase/anaphase Transition Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Actin Filament-based Process Cell-substrate Junction Assembly Proteasomal Protein Catabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Establishment Of Localization In Cell Positive Regulation Of Proteolysis Actin Filament Bundle Assembly Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Transferase Activity Negative Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Wnt Signaling Pathway Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Mitotic Sister Chromatid Segregation Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Chromosome Segregation Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process	Cell Development Anatomical Structure Morphogenesis Axon Guidance Movement Of Cell Or Subcellular Component Neuron Projection Development Locomotion Axonogenesis Anatomical Structure Development Bicarbonate Transport Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Neuron Development Chemotaxis Response To Growth Factor Cell Differentiation Neuron Projection Morphogenesis Cell Morphogenesis Developmental Process Neuron Differentiation Cell Morphogenesis Involved In Differentiation Actin Filament Capping Cell Projection Organization Blood Coagulation Multicellular Organismal Development Hemostasis Negative Regulation Of Actin Filament Depolymerization Response To External Stimulus Cell Projection Morphogenesis Regulation Of Actin Filament Depolymerization Cell Part Morphogenesis Chemical Homeostasis System Development Negative Regulation Of Actin Filament Polymerization Homeostatic Process Cellular Chemical Homeostasis Negative Regulation Of Protein Polymerization Ion Homeostasis Regulation Of Body Fluid Levels Negative Regulation Of Protein Complex Disassembly Wound Healing Generation Of Neurons Hemopoiesis Regulation Of Protein Depolymerization Nervous System Development Neurogenesis Regulation Of Protein Complex Disassembly Response To Wounding Cellular Homeostasis Immune System Development
Tagcloud ?			antiglobulin appointment bilirubin cared cytoskeletal cytoskeleton damaged delays discharged e508k epb41 epb42 erythrocyte incompatibility kernicterus neurologic newborn parent persisted phototherapy retesting return silico slc4a1 smear spherocytes spta1 sptb ugt1a1
Tagcloud (Difference) ?			antiglobulin appointment bilirubin cared cytoskeletal cytoskeleton damaged delays discharged e508k epb41 epb42 erythrocyte incompatibility kernicterus neurologic newborn parent persisted phototherapy retesting return silico slc4a1 smear spherocytes spta1 sptb ugt1a1
Tagcloud (Intersection) ?