KCTD6 and GSDMD

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KCTD6	GSDMD
Gene Name		potassium channel tetramerization domain containing 6	gasdermin D
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component
	Molecular Function	Ankyrin Binding
	Biological Process	Protein Homooligomerization	Cellular Response To Extracellular Stimulus
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: ACTN1 ACTN3 ANK1 C8orf33 CDC23 CTNND1 CUL3 EHHADH FAM124B GOLGA8EP GOLGA8F GRB7 GSDMD LNX1 PPIG PRPF31 SDCBP UBC ZCCHC10	1 interactors: KCTD6
Entrez ID		200845	79792
HPRD ID		13769	11014
Ensembl ID		ENSG00000168301	ENSG00000104518
Uniprot IDs		Q8NC69	A8K702 P57764
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Component Assembly Adherens Junction Organization Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Cellular Protein Catabolic Process Mitotic Metaphase Plate Congression Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Focal Adhesion Assembly Metaphase Plate Congression Modification-dependent Protein Catabolic Process Negative Regulation Of Wnt Signaling Pathway Cell Junction Assembly Proteolysis Involved In Cellular Protein Catabolic Process Cell-cell Junction Organization Cellular Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Protein Ubiquitination Regulation Of Canonical Wnt Signaling Pathway Establishment Of Chromosome Localization Regulation Of Cell Cycle Phase Transition Adherens Junction Assembly Protein Modification By Small Protein Conjugation Protein Catabolic Process Regulation Of Mitotic Sister Chromatid Separation Regulation Of Mitotic Metaphase/anaphase Transition Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Actin Filament-based Process Cell-substrate Junction Assembly Proteasomal Protein Catabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Establishment Of Localization In Cell Positive Regulation Of Proteolysis Actin Filament Bundle Assembly Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Transferase Activity Negative Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Wnt Signaling Pathway Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Mitotic Sister Chromatid Segregation Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Chromosome Segregation Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
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