KCTD6 and TBC1D2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KCTD6	TBC1D2
Description		potassium channel tetramerization domain containing 6	TBC1 domain family member 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol M Band	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cell Junction Cytoplasmic Vesicle Anchoring Junction
	Molecular Function	Protein Binding Ankyrin Binding Identical Protein Binding Cullin Family Protein Binding	GTPase Activator Activity Protein Binding Cadherin Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Negative Regulation Of Smoothened Signaling Pathway Protein Homooligomerization	Positive Regulation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		RUNX1 regulates estrogen receptor mediated transcription Neddylation Estrogen-dependent gene expression Antigen processing: Ubiquitination & Proteasome degradation	TBC/RABGAPs
Drugs
Diseases
GWAS		Hepcidin/transferrin saturation ratio ( 27846281) Refractive error ( 32231278) Systemic lupus erythematosus ( 28714469) vWF levels ( 30586737)	Femur bone mineral density x serum urate levels interaction ( 34046847) Metabolite levels ( 23823483) Post-traumatic stress disorder ( 26114229) Rate of ventricular enlargement ( 31711042) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		26 interacting genes: ACTN1 ACTN3 ANK1 BAG4 C8orf33 CDC23 CTNND1 ERBB2 FAM124B GOLGA8EP GOLGA8F GRB7 GSDMD LNX1 MOS NTAQ1 PICK1 PPIG PRPF31 PSMA1 REL SDCBP TBC1D2 TCEANC TEPSIN ZCCHC10	10 interacting genes: AURKA BUB1 CCND1 DCC GABARAPL1 KCTD6 MAP1LC3A MLH3 PDGFRL UBC
Entrez ID		200845	55357
HPRD ID		13769	11624
Ensembl ID		ENSG00000168301	ENSG00000095383
Uniprot IDs		Q8NC69	Q9BYX2
PDB IDs			2DHK
Enriched GO Terms of Interacting Partners?			Ubiquitin Protein Ligase Binding Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Liver Regeneration Response To Iron Ion Positive Regulation Of Cell Cycle Process Animal Organ Regeneration Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric Histone H2A Kinase Activity Mitophagy Autophagosome Maturation Autophagosome Membrane Regulation Of Mitotic Cell Cycle Phase Transition Cyclin D1-CDK4 Complex Cyclin D1-CDK6 Complex Positive Regulation Of Cell Cycle Platelet-derived Growth Factor Beta-receptor Activity Platelet-derived Growth Factor Receptor Activity Microtubule Autophagy Of Mitochondrion Autophagosome Chiasma Microtubule Organizing Center Response To Nutrient Levels Re-entry Into Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Cell Division Regulation Of Cell Cycle Phase Transition Regulation Of G2/M Transition Of Mitotic Cell Cycle Liver Development Cytosol Regulation Of Mitotic Nuclear Division Meiotic Sister Chromatid Cohesion, Centromeric Dorsal/ventral Axon Guidance Spinal Cord Ventral Commissure Morphogenesis Platelet Activating Factor Receptor Activity Macromolecule Catabolic Process Spindle Assembly Involved In Female Meiosis I Germinal Vesicle Histone H3S10 Kinase Activity Positive Regulation Of Oocyte Maturation Autophagosome Organization Phospholipid Binding Autophagosome Assembly Satellite DNA Binding Cellular Response To Oxygen-glucose Deprivation Positive Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Protein Kinase Activity Regeneration
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?