KCTD6 and ACTN3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KCTD6	ACTN3
Gene Name		potassium channel tetramerization domain containing 6	actinin, alpha 3 (gene/pseudogene)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Cytosol Actin Filament Focal Adhesion Pseudopodium Extracellular Vesicular Exosome
	Molecular Function	Ankyrin Binding	Actin Binding Integrin Binding Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Protein Homodimerization Activity
	Biological Process	Protein Homooligomerization	Muscle Filament Sliding Regulation Of Apoptotic Process Focal Adhesion Assembly
Pathways			Striated Muscle Contraction Nephrin interactions
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Protein-Protein Interactions		19 interactors: ACTN1 ACTN3 ANK1 C8orf33 CDC23 CTNND1 CUL3 EHHADH FAM124B GOLGA8EP GOLGA8F GRB7 GSDMD LNX1 PPIG PRPF31 SDCBP UBC ZCCHC10	17 interactors: ABI3 ACTN1 ACTN2 ACTN4 ADORA2A BRCA1 C1orf94 KCTD6 MYPN NEBL NRAP PLEKHG2 REL RNF111 SUMO1P1 TRAF1 TRAF2
Entrez ID		200845	89
HPRD ID		13769	02148
Ensembl ID		ENSG00000168301	ENSG00000248746
Uniprot IDs		Q8NC69	B4DZQ2 Q08043 Q4VAM3
PDB IDs			1TJT 1WKU 3LUE
Enriched GO Terms of Interacting Partners?		Cellular Component Assembly Adherens Junction Organization Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Cellular Protein Catabolic Process Mitotic Metaphase Plate Congression Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Focal Adhesion Assembly Metaphase Plate Congression Modification-dependent Protein Catabolic Process Negative Regulation Of Wnt Signaling Pathway Cell Junction Assembly Proteolysis Involved In Cellular Protein Catabolic Process Cell-cell Junction Organization Cellular Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Protein Ubiquitination Regulation Of Canonical Wnt Signaling Pathway Establishment Of Chromosome Localization Regulation Of Cell Cycle Phase Transition Adherens Junction Assembly Protein Modification By Small Protein Conjugation Protein Catabolic Process Regulation Of Mitotic Sister Chromatid Separation Regulation Of Mitotic Metaphase/anaphase Transition Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Actin Filament-based Process Cell-substrate Junction Assembly Proteasomal Protein Catabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Establishment Of Localization In Cell Positive Regulation Of Proteolysis Actin Filament Bundle Assembly Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Transferase Activity Negative Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Wnt Signaling Pathway Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Mitotic Sister Chromatid Segregation Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Chromosome Segregation Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process	Protein Localization To Tight Junction Regulation Of Cell Death Cellular Component Assembly Protein Localization To Cell Junction Platelet Degranulation Regulation Of Apoptotic Process Actin Filament-based Process Actin Crosslink Formation Blood Coagulation Hemostasis Protein Polyubiquitination Focal Adhesion Assembly Platelet Activation Apoptotic Process Cell Junction Assembly Regulation Of Extrinsic Apoptotic Signaling Pathway NIK/NF-kappaB Signaling Cell-cell Junction Organization Programmed Cell Death Protein Autoubiquitination Cell Death Death Regulation Of Body Fluid Levels Tight Junction Assembly Adherens Junction Assembly Actin Cytoskeleton Organization Wound Healing Cytoskeleton Organization Positive Regulation Of Ion Transmembrane Transporter Activity Cell-substrate Junction Assembly Protein Homooligomerization Positive Regulation Of Transporter Activity I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Cardiac Muscle Thin Filament Assembly Actin Filament Bundle Assembly Response To Wounding Regulation Of Signal Transduction Actin Filament Organization Apical Junction Assembly Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Ion Transmembrane Transport Myofibril Assembly Exocytosis Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of Cytokine Production Adherens Junction Organization Regulation Of Signaling Cellular Response To Tumor Necrosis Factor
Tagcloud ?			ace bdkrb2 chi2 cl cmj competition counter discriminate distributions elite explosive forward genotypic italian italians jump leg look players sedentary sj soccer squat stepwise strength top traits variance
Tagcloud (Difference) ?			ace bdkrb2 chi2 cl cmj competition counter discriminate distributions elite explosive forward genotypic italian italians jump leg look players sedentary sj soccer squat stepwise strength top traits variance
Tagcloud (Intersection) ?