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DYNC1I1 and TK1
Number of citations of the paper that reports this interaction (PubMedID
21900206
)
0
Data Source:
BioGRID
(two hybrid)
DYNC1I1
TK1
Description
dynein cytoplasmic 1 intermediate chain 1
thymidine kinase 1
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Kinetochore
Spindle Pole
Nucleus
Chromosome
Cytoplasm
Cytosol
Cytoskeleton
Cytoplasmic Dynein Complex
Microtubule
Dynein Complex
Vesicle
Cytoplasmic Ribonucleoprotein Granule
Perinuclear Region Of Cytoplasm
Recycling Endosome
Nucleus
Cytoplasm
Cytosol
Molecular Function
Cytoskeletal Motor Activity
Microtubule Motor Activity
Protein Binding
Microtubule Binding
Spectrin Binding
Dynein Light Chain Binding
Dynein Heavy Chain Binding
Nucleotide Binding
Thymidine Kinase Activity
Protein Binding
ATP Binding
Zinc Ion Binding
Kinase Activity
Transferase Activity
Identical Protein Binding
Metal Ion Binding
Biological Process
Microtubule-based Movement
Transport Along Microtubule
Vesicle Transport Along Microtubule
Nucleobase-containing Compound Metabolic Process
Deoxyribonucleoside Monophosphate Biosynthetic Process
Thymidine Metabolic Process
Thymidine Biosynthetic Process
Protein Homotetramerization
DNA Biosynthetic Process
DNA Synthesis Involved In Mitotic DNA Replication
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
HCMV Early Events
Aggrephagy
Aggrephagy
EML4 and NUDC in mitotic spindle formation
G1/S-Specific Transcription
Pyrimidine salvage
Drugs
Dithioerythritol
Thymidine 5'-triphosphate
Diseases
GWAS
Dementia and core Alzheimer's disease neuropathologic changes (
25188341
)
Heel bone mineral density (
30598549
)
Hip circumference adjusted for BMI (
28552196
)
Immune reponse to smallpox (secreted IL-10) (
22610502
)
Knee osteoarthritis (
27696742
)
Multisite chronic pain (
31194737
33830993
)
Obesity-related traits (
23251661
)
Oily fish consumption (
32066663
)
Pork consumption (
32066663
)
Refractive error (
32231278
)
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
Leukocyte telomere length (
32109421
)
Mean corpuscular hemoglobin (
27863252
32888494
)
Mean corpuscular volume (
27863252
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Red cell distribution width (
27863252
28957414
32888494
)
Interacting Genes
35 interacting genes:
ACADM
ANXA7
BICD1
CADM4
CDKN1A
DCTN1
DNM2
DYNLL1
DYNLL2
DYNLRB1
DYNLT1
DYNLT3
EMILIN1
FAM110A
FAM83D
FBP1
GRB7
GSK3B
KAT7
LCOR
MCC
NAGK
NUDT21
PIN1
RAP1GAP
RBPMS
RCC1
RUNDC3B
SMN1
STAU1
TAOK1
TK1
TRIM58
WDCP
YTHDF1
166 interacting genes:
A1BG
A2M
AAMP
ABHD4
ACTB
ACTL6B
ACTR1B
ADAMTS10
ADD1
AGAP1
ALAS1
ALB
APLP1
APP
ARFGAP1
ATG16L2
ATP5F1B
ATP6V1A
ATXN3
BAG6
BOLA2
BOLA2B
CARHSP1
CCDC90B
CDC20
CDK1
CDK4
CDKN1A
CENPB
CFTR
CHGB
CLEC3B
COL11A2
COL4A2
COL4A5
COPS6
CPNE6
CRIP2
CRMP1
CSAD
DACT1
DALRD3
DCAF13
DDAH2
DEAF1
DMPK
DOCK7
DRAP1
DUS2
DYNC1I1
DYNC2I1
DYNLT2B
EEF1A1
EIF3G
EIF4A2
EIF6
ERG28
EXT2
EZH2
F13A1
FAF1
FAM20C
FBN3
FGB
FLAD1
FST
FZR1
GAPDH
GDF9
GDI1
GET3
GLB1
GPCPD1
HADHB
HERC3
HMGXB3
HSPBAP1
IER3IP1
IGHM
IMMT
INPP5K
INTS11
ITSN1
JADE1
JMJD1C
KDM6B
KIF21B
KIF5A
KLHL23
KLHL5
KMT2B
LRIF1
MAGEA4
MAST2
MED31
METTL23
MKI67
MPP1
MPPED1
MRFAP1
MRPL20-AS1
MRPL37
MSH2
NEUROD2
NGFR
NKIRAS2
NMT2
NRBP1
ODC1
PAAF1
PDE4DIP
PJA1
PKM
PLD3
PLXNA3
PPP4C
PRMT1
PROC
PSME1
PTPN4
PTPRK
QARS1
RBBP4
RBM48
REX1BD
RPA1
RPL13
RPS2
RUVBL1
RXRA
SDF4
SEMA5B
SEPTIN6
SETDB1
SEZ6L2
SMC5
SNX1
SP110
SULT1A3
SUMO2
SUMO3
TAF1C
THOC3
TIAM2
TLE1
TMSB4X
TP53
TRIM46
TRMT2A
TSC2
TTC38
TUBA1A
TUBB2A
TUBB3
TYK2
UBC
UNC119
UPF2
USP4
VMA22
WDR18
WDR73
WIZ
ZBTB16
ZNF431
ZXDC
Entrez ID
1780
7083
HPRD ID
04798
01771
Ensembl ID
ENSG00000158560
ENSG00000167900
Uniprot IDs
A4D1I7
O14576
Q8N542
A0A384MDV9
K7ERV3
K7ES52
P04183
PDB IDs
1W4R
1XBT
2ORV
2WVJ
Enriched GO Terms of Interacting Partners
?
Dynein Intermediate Chain Binding
Dynein Complex
Cytoplasmic Dynein Complex
Microtubule-based Process
Microtubule
Microtubule Associated Complex
Tau Protein Binding
Cytoplasmic Stress Granule
Microtubule-based Movement
Centrosome
Regulation Of Microtubule-based Process
Regulation Of Microtubule Cytoskeleton Organization
Regulation Of Intracellular Transport
Stress Granule Assembly
Identical Protein Binding
Microtubule Cytoskeleton Organization
Positive Regulation Of Protein Localization To Centrosome
Cellular Component Assembly
Regulation Of Long-term Synaptic Potentiation
Cytoplasm
Secretory Vesicle
Regulation Of DNA Replication
Ciliary Tip
Regulation Of Cell Cycle
Microtubule Cytoskeleton Organization Involved In Mitosis
Response To Phorbol 13-acetate 12-myristate
Intracellular MRNA Localization
Regulation Of Protein Localization To Centrosome
Positive Regulation Of Intracellular Transport
Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
MRNA Binding
Microtubule Anchoring At Microtubule Organizing Center
Microtubule Cytoskeleton
Viral Process
Mitotic Cell Cycle Phase Transition
Dynactin Binding
Replicative Senescence
Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
MRNA Export From Nucleus
Membraneless Organelle Assembly
Regulation Of DNA-templated DNA Replication Initiation
Regulation Of Cellular Component Organization
Negative Regulation Of Phosphate Metabolic Process
Cell Cycle Phase Transition
Scaffold Protein Binding
Negative Regulation Of Cellular Response To Vascular Endothelial Growth Factor Stimulus
Cytoskeleton
Protein Kinase Binding
Transport Along Microtubule
Organelle Localization
Cytoplasm
Macromolecule Metabolic Process
Protein Metabolic Process
Platelet Alpha Granule Lumen
Chromatin Organization
Blood Microparticle
Negative Regulation Of Cell Cycle G1/S Phase Transition
Chromatin Remodeling
Regulation Of Cell Cycle G1/S Phase Transition
Negative Regulation Of Cell Cycle Phase Transition
Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Cell Cycle Phase Transition
Regulation Of Mitotic Cell Cycle
Extracellular Exosome
Cytosol
Regulation Of DNA Replication
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Protein Binding
Nucleoplasm
Positive Regulation Of Protein Catabolic Process
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Mitotic Cell Cycle
Positive Regulation Of Ubiquitin-protein Transferase Activity
Nuclear Matrix
Regulation Of Protein Catabolic Process
DNA Synthesis Involved In Mitotic DNA Replication
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Macromolecule Biosynthetic Process
Chromosome, Telomeric Region
Positive Regulation Of Protein Metabolic Process
Cytoskeleton
Negative Regulation Of Cell Cycle Process
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Protein Tag Activity
Developmental Process
Growth Cone
Protein Modification Process
Cellular Response To Norepinephrine Stimulus
Response To Norepinephrine
Mitotic DNA Damage Checkpoint Signaling
Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process
Oocyte Growth
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Tagcloud (Difference)
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Tagcloud (Intersection)
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