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DYNC1I1 and FBP1
Number of citations of the paper that reports this interaction (PubMedID
21900206
)
0
Data Source:
BioGRID
(two hybrid)
DYNC1I1
FBP1
Description
dynein cytoplasmic 1 intermediate chain 1
fructose-bisphosphatase 1
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Kinetochore
Spindle Pole
Nucleus
Chromosome
Cytoplasm
Cytosol
Cytoskeleton
Cytoplasmic Dynein Complex
Microtubule
Dynein Complex
Vesicle
Cytoplasmic Ribonucleoprotein Granule
Perinuclear Region Of Cytoplasm
Recycling Endosome
Extracellular Space
Nucleus
Cytoplasm
Cytosol
Extracellular Exosome
Molecular Function
Cytoskeletal Motor Activity
Microtubule Motor Activity
Protein Binding
Microtubule Binding
Spectrin Binding
Dynein Light Chain Binding
Dynein Heavy Chain Binding
Catalytic Activity
Protein Binding
AMP Binding
Hydrolase Activity
Phosphatase Activity
Fructose 1,6-bisphosphate 1-phosphatase Activity
Phosphoric Ester Hydrolase Activity
Identical Protein Binding
Metal Ion Binding
Monosaccharide Binding
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Biological Process
Microtubule-based Movement
Transport Along Microtubule
Vesicle Transport Along Microtubule
Negative Regulation Of Transcription By RNA Polymerase II
Carbohydrate Metabolic Process
Fructose Metabolic Process
Fructose 6-phosphate Metabolic Process
Gluconeogenesis
Regulation Of Gluconeogenesis
Negative Regulation Of Cell Growth
Fructose 1,6-bisphosphate Metabolic Process
Response To Nutrient Levels
Cellular Response To Insulin Stimulus
Negative Regulation Of Glycolytic Process
Negative Regulation Of Ras Protein Signal Transduction
Cellular Response To Magnesium Ion
Cellular Response To CAMP
Cellular Response To Xenobiotic Stimulus
Cellular Hyperosmotic Salinity Response
Cellular Hypotonic Salinity Response
Cellular Response To Raffinose
Cellular Response To Phorbol 13-acetate 12-myristate
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
HCMV Early Events
Aggrephagy
Aggrephagy
EML4 and NUDC in mitotic spindle formation
Gluconeogenesis
Drugs
Adenosine phosphate
2,5-Anhydroglucitol-1,6-Biphosphate
{4-[3-(6,7-Diethoxy-Quinazolin-4-Ylamino)-Phenyl]-Thiazol-2-Yl}-Methanol
Mdl-29951
Fructose-6-phosphate
MB-07803
Managlinat dialanetil
N-[7-(3-AMINOPHENYL)-5-METHOXY-1,3-BENZOXAZOL-2-YL]-2,5-DICHLOROBENZENESULFONAMIDE
2,5-DICHLORO-N-(5-CHLORO-1,3-BENZOXAZOL-2-YL)BENZENESULFONAMIDE
2,5-DICHLORO-N-[5-METHOXY-7-(6-METHOXYPYRIDIN-3-YL)-1,3-BENZOXAZOL-2-YL]BENZENESULFONAMIDE
4-AMINO-N-[(2-SULFANYLETHYL)CARBAMOYL]BENZENESULFONAMIDE
Diseases
Fructose-1,6-bisphosphatase deficiency
GWAS
Dementia and core Alzheimer's disease neuropathologic changes (
25188341
)
Heel bone mineral density (
30598549
)
Hip circumference adjusted for BMI (
28552196
)
Immune reponse to smallpox (secreted IL-10) (
22610502
)
Knee osteoarthritis (
27696742
)
Multisite chronic pain (
31194737
33830993
)
Obesity-related traits (
23251661
)
Oily fish consumption (
32066663
)
Pork consumption (
32066663
)
Refractive error (
32231278
)
Cerebrospinal fluid t-tau:AB1-42 ratio (
28641921
)
Colorectal or endometrial cancer (
26621817
)
Obesity-related traits (
23251661
)
Interacting Genes
35 interacting genes:
ACADM
ANXA7
BICD1
CADM4
CDKN1A
DCTN1
DNM2
DYNLL1
DYNLL2
DYNLRB1
DYNLT1
DYNLT3
EMILIN1
FAM110A
FAM83D
FBP1
GRB7
GSK3B
KAT7
LCOR
MCC
NAGK
NUDT21
PIN1
RAP1GAP
RBPMS
RCC1
RUNDC3B
SMN1
STAU1
TAOK1
TK1
TRIM58
WDCP
YTHDF1
40 interacting genes:
ACTN1
APC
ASCC2
ASL
ATP5MF
AXIN2
BCL10
BCL2L1
BIN1
BMPR1A
BRAF
BUB1
CSNK1E
CTNNA1
DCC
DNMT1
DYNC1I1
ERBB2
FLCN
FXR2
HDAC6
HSPA8
KLRC2
LNX1
MLH3
MSH2
NOTCH1
PCNX4
PIM2
POT1
PRKN
PTK2
PTPRJ
RB1
RELA
RNF183
STK11
TERF1
TLR2
TRIM28
Entrez ID
1780
2203
HPRD ID
04798
01973
Ensembl ID
ENSG00000158560
ENSG00000165140
Uniprot IDs
A4D1I7
O14576
Q8N542
P09467
Q2TU34
PDB IDs
1FTA
2FHY
2FIE
2FIX
2JJK
2VT5
2WBB
2WBD
2Y5K
2Y5L
3A29
3KBZ
3KC0
3KC1
4MJO
5LDZ
5PZQ
5PZR
5PZS
5PZT
5PZU
5PZV
5PZW
5PZX
5PZY
5PZZ
5Q00
5Q01
5Q02
5Q03
5Q04
5Q05
5Q06
5Q07
5Q08
5Q09
5Q0A
5Q0B
5ZWK
6LS5
6LW2
7C9Q
7CVH
7CVN
7CWE
7EZF
7EZP
7EZR
7WJV
7WVB
8XBK
Enriched GO Terms of Interacting Partners
?
Dynein Intermediate Chain Binding
Dynein Complex
Cytoplasmic Dynein Complex
Microtubule-based Process
Microtubule
Microtubule Associated Complex
Tau Protein Binding
Cytoplasmic Stress Granule
Microtubule-based Movement
Centrosome
Regulation Of Microtubule-based Process
Regulation Of Microtubule Cytoskeleton Organization
Regulation Of Intracellular Transport
Stress Granule Assembly
Identical Protein Binding
Microtubule Cytoskeleton Organization
Positive Regulation Of Protein Localization To Centrosome
Cellular Component Assembly
Regulation Of Long-term Synaptic Potentiation
Cytoplasm
Secretory Vesicle
Regulation Of DNA Replication
Ciliary Tip
Regulation Of Cell Cycle
Microtubule Cytoskeleton Organization Involved In Mitosis
Response To Phorbol 13-acetate 12-myristate
Intracellular MRNA Localization
Regulation Of Protein Localization To Centrosome
Positive Regulation Of Intracellular Transport
Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
MRNA Binding
Microtubule Anchoring At Microtubule Organizing Center
Microtubule Cytoskeleton
Viral Process
Mitotic Cell Cycle Phase Transition
Dynactin Binding
Replicative Senescence
Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
MRNA Export From Nucleus
Membraneless Organelle Assembly
Regulation Of DNA-templated DNA Replication Initiation
Regulation Of Cellular Component Organization
Negative Regulation Of Phosphate Metabolic Process
Cell Cycle Phase Transition
Scaffold Protein Binding
Negative Regulation Of Cellular Response To Vascular Endothelial Growth Factor Stimulus
Cytoskeleton
Protein Kinase Binding
Transport Along Microtubule
Organelle Localization
Regulation Of Programmed Cell Death
Regulation Of Apoptotic Process
Regulation Of Nervous System Development
Regulation Of Neurogenesis
Positive Regulation Of Metabolic Process
Negative Regulation Of Developmental Process
Regulation Of Cellular Component Organization
Cell Surface Receptor Signaling Pathway
Regulation Of Cell Development
Cellular Response To Stress
Ubiquitin Protein Ligase Binding
Positive Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Nervous System Development
Positive Regulation Of Signal Transduction
Regulation Of Cell Communication
Regulation Of Signaling
Negative Regulation Of Cellular Component Organization
Negative Regulation Of Apoptotic Process
Regulation Of Cell Population Proliferation
Regulation Of Primary Metabolic Process
Regulation Of Multicellular Organismal Process
Negative Regulation Of Programmed Cell Death
Regulation Of Developmental Process
Regulation Of Protein Localization
Immune Response-activating Cell Surface Receptor Signaling Pathway
Regulation Of Protein Metabolic Process
Regulation Of Signal Transduction
Beta-catenin Binding
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Cell Differentiation
Regulation Of Protein Modification Process
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Metabolic Process
Positive Regulation Of Multicellular Organismal Process
Anatomical Structure Morphogenesis
Positive Regulation Of Catabolic Process
Regulation Of Phosphorylation
Apoptotic Process
Regulation Of Phosphorus Metabolic Process
Negative Regulation Of Neurogenesis
Negative Regulation Of Metabolic Process
Regulation Of Macromolecule Metabolic Process
Identical Protein Binding
Positive Regulation Of Neurogenesis
Programmed Cell Death
Regulation Of Growth
Cell Death
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Tagcloud (Intersection)
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