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DYNC1I1 and NUDT21
Number of citations of the paper that reports this interaction (PubMedID
21900206
)
0
Data Source:
BioGRID
(two hybrid)
DYNC1I1
NUDT21
Description
dynein cytoplasmic 1 intermediate chain 1
nudix hydrolase 21
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Kinetochore
Spindle Pole
Nucleus
Chromosome
Cytoplasm
Cytosol
Cytoskeleton
Cytoplasmic Dynein Complex
Microtubule
Dynein Complex
Vesicle
Cytoplasmic Ribonucleoprotein Granule
Perinuclear Region Of Cytoplasm
Recycling Endosome
Nucleus
Nucleoplasm
Cytoplasm
Centrosome
MRNA Cleavage And Polyadenylation Specificity Factor Complex
MRNA Cleavage Factor Complex
Nuclear Body
Centriolar Satellite
Paraspeckles
Molecular Function
Cytoskeletal Motor Activity
Microtubule Motor Activity
Protein Binding
Microtubule Binding
Spectrin Binding
Dynein Light Chain Binding
Dynein Heavy Chain Binding
Chromatin Binding
RNA Binding
MRNA Binding
Protein Binding
MRNA 3'-UTR AU-rich Region Binding
Identical Protein Binding
Protein Homodimerization Activity
Histone Deacetylase Binding
Biological Process
Microtubule-based Movement
Transport Along Microtubule
Vesicle Transport Along Microtubule
MRNA Processing
Post-transcriptional Regulation Of Gene Expression
Cell Differentiation
MRNA 3'-end Processing
Protein Tetramerization
Protein Heterotetramerization
MRNA Alternative Polyadenylation
Co-transcriptional MRNA 3'-end Processing, Cleavage And Polyadenylation Pathway
Positive Regulation Of Stem Cell Differentiation
Positive Regulation Of Pro-B Cell Differentiation
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
HCMV Early Events
Aggrephagy
Aggrephagy
EML4 and NUDC in mitotic spindle formation
mRNA 3'-end processing
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Transcription Termination
Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS
Dementia and core Alzheimer's disease neuropathologic changes (
25188341
)
Heel bone mineral density (
30598549
)
Hip circumference adjusted for BMI (
28552196
)
Immune reponse to smallpox (secreted IL-10) (
22610502
)
Knee osteoarthritis (
27696742
)
Multisite chronic pain (
31194737
33830993
)
Obesity-related traits (
23251661
)
Oily fish consumption (
32066663
)
Pork consumption (
32066663
)
Refractive error (
32231278
)
Interacting Genes
35 interacting genes:
ACADM
ANXA7
BICD1
CADM4
CDKN1A
DCTN1
DNM2
DYNLL1
DYNLL2
DYNLRB1
DYNLT1
DYNLT3
EMILIN1
FAM110A
FAM83D
FBP1
GRB7
GSK3B
KAT7
LCOR
MCC
NAGK
NUDT21
PIN1
RAP1GAP
RBPMS
RCC1
RUNDC3B
SMN1
STAU1
TAOK1
TK1
TRIM58
WDCP
YTHDF1
119 interacting genes:
A2M
ATXN1
CARM1
CDC42
CEBPA
CEP126
CLP1
CPSF6
CPSF7
CTNND2
DBN1
DNMT3L
DYNC1I1
EED
EEF1G
ESR1
EXOSC6
F13A1
FAM90A1
FBN3
FLAD1
FUNDC2
GOLGA2
HSF4
IKZF1
ITCH
JMJD1C
KIFAP3
KRT75
MASP1
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-2
MIR138-1
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200B
MIR205
MIR206
MIR20A
MIR214
MIR221
MIR25
MIR29A
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-2
MIR9-2
MIR92A1
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
MYL6
NEDD4
NGEF
NIF3L1
NTAQ1
POLR2C
PSMF1
PSPC1
PTN
PYCR1
RBM48
RCC1
RNF19A
RPLP1
S100PBP
SEM1
SEMA5B
SF3B1
SHC1
SLC44A1
SNCAIP
SNRNP70
SPAG8
SRPK1
TCERG1
TEPSIN
TLE1
TRA2A
TRIM23
TRIM27
WWOX
ZNF655
Entrez ID
1780
11051
HPRD ID
04798
05400
Ensembl ID
ENSG00000158560
ENSG00000167005
Uniprot IDs
A4D1I7
O14576
Q8N542
O43809
PDB IDs
2CL3
2J8Q
3BAP
3BHO
3MDG
3MDI
3N9U
3P5T
3P6Y
3Q2S
3Q2T
5R4P
5R4Q
5R4R
5R4S
5R4T
5R4U
5R64
5R65
5R66
5R67
Enriched GO Terms of Interacting Partners
?
Dynein Intermediate Chain Binding
Dynein Complex
Cytoplasmic Dynein Complex
Microtubule-based Process
Microtubule
Microtubule Associated Complex
Tau Protein Binding
Cytoplasmic Stress Granule
Microtubule-based Movement
Centrosome
Regulation Of Microtubule-based Process
Regulation Of Microtubule Cytoskeleton Organization
Regulation Of Intracellular Transport
Stress Granule Assembly
Identical Protein Binding
Microtubule Cytoskeleton Organization
Positive Regulation Of Protein Localization To Centrosome
Cellular Component Assembly
Regulation Of Long-term Synaptic Potentiation
Cytoplasm
Secretory Vesicle
Regulation Of DNA Replication
Ciliary Tip
Regulation Of Cell Cycle
Microtubule Cytoskeleton Organization Involved In Mitosis
Response To Phorbol 13-acetate 12-myristate
Intracellular MRNA Localization
Regulation Of Protein Localization To Centrosome
Positive Regulation Of Intracellular Transport
Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
MRNA Binding
Microtubule Anchoring At Microtubule Organizing Center
Microtubule Cytoskeleton
Viral Process
Mitotic Cell Cycle Phase Transition
Dynactin Binding
Replicative Senescence
Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
MRNA Export From Nucleus
Membraneless Organelle Assembly
Regulation Of DNA-templated DNA Replication Initiation
Regulation Of Cellular Component Organization
Negative Regulation Of Phosphate Metabolic Process
Cell Cycle Phase Transition
Scaffold Protein Binding
Negative Regulation Of Cellular Response To Vascular Endothelial Growth Factor Stimulus
Cytoskeleton
Protein Kinase Binding
Transport Along Microtubule
Organelle Localization
MiRNA-mediated Post-transcriptional Gene Silencing
Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
RISC Complex
MRNA Base-pairing Post-transcriptional Repressor Activity
Regulatory NcRNA-mediated Gene Silencing
Post-transcriptional Regulation Of Gene Expression
Negative Regulation Of Gene Expression
MRNA 3'-UTR Binding
MiRNA-mediated Gene Silencing By Inhibition Of Translation
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
Extracellular Vesicle
MiRNA-mediated Gene Silencing By MRNA Destabilization
Negative Regulation Of Angiogenesis
Negative Regulation Of Vasculature Development
Negative Regulation Of Translation
Regulation Of Angiogenesis
Regulation Of Vasculature Development
Negative Regulation Of Vascular Endothelial Growth Factor Production
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Blood Vessel Endothelial Cell Migration
MRNA Destabilization
Positive Regulation Of MRNA Metabolic Process
Negative Regulation Of Cell Migration
RNA Destabilization
Negative Regulation Of Cytokine Production
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Cell Motility
Positive Regulation Of MRNA Catabolic Process
Negative Regulation Of Locomotion
Regulation Of Macromolecule Metabolic Process
Regulation Of Endothelial Cell Migration
Negative Regulation Of Multicellular Organismal Process
Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Negative Regulation Of Endothelial Cell Migration
Positive Regulation Of Tissue Remodeling
Negative Regulation Of Developmental Process
Negative Regulation Of Sprouting Angiogenesis
Regulation Of Metabolic Process
Positive Regulation Of Connective Tissue Replacement
Regulation Of Translation
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Regulation Of Anatomical Structure Morphogenesis
Negative Regulation Of Signal Transduction
Regulation Of Sprouting Angiogenesis
Negative Regulation Of Protein Metabolic Process
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