XIRP1 and ACTA1

Number of citations of the paper that reports this interaction (PMID 15454575)
24

Data Source:
HPRD (in vitro)

		XIRP1	ACTA1
Gene Name		xin actin-binding repeat containing 1	actin, alpha 1, skeletal muscle
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Fascia Adherens	Stress Fiber Extracellular Space Cytosol Striated Muscle Thin Filament Actin Filament Actin Cytoskeleton Sarcomere Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Actin Binding Protein Binding Poly(A) RNA Binding	Structural Constituent Of Cytoskeleton Protein Binding ATP Binding Myosin Binding ADP Binding
	Biological Process	Negative Regulation Of Cell Proliferation Regulation Of Membrane Potential Sarcomere Organization Cardiac Muscle Cell Development	Muscle Contraction Response To Mechanical Stimulus Response To Extracellular Stimulus Response To Lithium Ion Cell Growth Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Skeletal Muscle Fiber Adaptation Response To Steroid Hormone Skeletal Muscle Fiber Development
Pathways			Striated Muscle Contraction
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: ACTA1 ENAH EVL FLNC NEB NEBL VASP	107 interactors: ABL1 ABRA ACTR10 ACTR1B ADSS AFAP1 AIF1 AJUBA AMOT CCIN CCT2 CCT4 CCT5 CFL1 CLIC5 CNN1 CORO2B COTL1 CTNND1 CTTN CYFIP1 CYTH1 DHX9 DLG1 DMD DNASE1 DNMBP DTNA EGFR EPB41 EPB41L2 EPS8 FGD4 FHOD1 FSCN1 GAS2 GAS7 GC GSN HCLS1 HDAC4 HIP1R HTRA2 IQGAP1 ITGA2 ITPKA KIF23 KLHL20 LASP1 MACF1 MAP1A MIB2 MINPP1 MYL1 MYLK MYO10 MYO6 MYO7A MYO9B NEXN NR3C2 NRAP PAK1 PARVA PCYT1B PFDN1 PFN1 PHACTR1 PLD1 PPP1R9B PRKCA PRKCD PRKCE RAC1 RPS6KB1 S100A1 S100A4 SCIN SMTN SNCA SORBS1 SPRR1A SPTA1 SPTAN1 SPTBN2 TAGLN TJP1 TLN1 TMSB4X TMSB4Y TNNI1 TNNI3 TNNI3K TP53 TPM2 TPM3 TRIM55 TRIM63 TTN USP25 USP6NL UTRN VASP VAV1 VCL VIL1 XIRP1
Entrez ID		165904	58
HPRD ID		16727	00030
Ensembl ID		ENSG00000168334	ENSG00000143632
Uniprot IDs		Q702N8	P68133 Q5T8M7
PDB IDs			1T44
Enriched GO Terms of Interacting Partners?		Actin Filament-based Process Actin Filament Organization Actin Cytoskeleton Organization Cell Development Actin Polymerization Or Depolymerization Cytoskeleton Organization Muscle Structure Development Striated Muscle Cell Development Muscle Cell Development Anatomical Structure Development Movement Of Cell Or Subcellular Component Regulation Of Actin Filament Length Striated Muscle Cell Differentiation Muscle Filament Sliding Actin-myosin Filament Sliding Developmental Process Cell Differentiation Cellular Component Assembly Actin-mediated Cell Contraction Muscle Cell Differentiation Regulation Of Cellular Component Size Muscle Fiber Development Regulation Of Actin Cytoskeleton Organization Anatomical Structure Formation Involved In Morphogenesis Actin Filament-based Movement Axon Guidance Protein Homotetramerization Regulation Of Actin Filament-based Process System Development Anatomical Structure Morphogenesis Myofibril Assembly Cardiac Muscle Thin Filament Assembly Regulation Of Cytoskeleton Organization Axonogenesis Multicellular Organismal Development Protein Tetramerization Neural Tube Closure Positive Regulation Of Actin Filament Polymerization T Cell Receptor Signaling Pathway Axon Development Actomyosin Structure Organization Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Protein Polymerization Chemotaxis Skeletal Muscle Fiber Adaptation Neural Tube Formation Neuron Projection Morphogenesis Organelle Organization Antigen Receptor-mediated Signaling Pathway Embryonic Epithelial Tube Formation	Actin Filament-based Process Actin Cytoskeleton Organization Cytoskeleton Organization Actin Filament Organization Regulation Of Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Movement Of Cell Or Subcellular Component Regulation Of Actin Filament-based Process Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Cellular Component Organization Regulation Of Actin Filament Polymerization Regulation Of Organelle Organization Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Actin Filament-based Movement Muscle Contraction Muscle System Process Cell Projection Organization Organelle Organization Negative Regulation Of Protein Polymerization Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Cytoskeleton Organization Cellular Component Assembly Developmental Process Anatomical Structure Morphogenesis Anatomical Structure Development Negative Regulation Of Protein Complex Assembly System Development Actin-mediated Cell Contraction Response To Wounding Locomotion Cell Development Response To External Stimulus Cell Differentiation Wound Healing Multicellular Organismal Development Cell Morphogenesis Negative Regulation Of Cytoskeleton Organization Positive Regulation Of Cellular Component Biogenesis Tissue Development Cell Projection Morphogenesis Chemotaxis Positive Regulation Of Organelle Organization Cell Part Morphogenesis Neuron Development Actin Polymerization Or Depolymerization Blood Coagulation Hemostasis Cell Junction Assembly
Tagcloud ?		0x 1x adamts13 aspm atp6v0a2 bioinformatic bl chickens col12a1 fowl grm5 interpretations jungle lrp2 obscn plau ppp1ca prkdc resequencing rnf168 sanger sl slv smyth stab2 ubc ubiquitinylation vitiliginous vitiligo	annotation assembled biomedical contigs cox1 discover eef1a1 eef1g ends est ests expand gluconeogenesis libraries livestock loin normalized ontology pfam pig pituitary porcine singletons sla slc25a6 susflecks tags transducin wd40
Tagcloud (Difference) ?		0x 1x adamts13 aspm atp6v0a2 bioinformatic bl chickens col12a1 fowl grm5 interpretations jungle lrp2 obscn plau ppp1ca prkdc resequencing rnf168 sanger sl slv smyth stab2 ubc ubiquitinylation vitiliginous vitiligo	annotation assembled biomedical contigs cox1 discover eef1a1 eef1g ends est ests expand gluconeogenesis libraries livestock loin normalized ontology pfam pig pituitary porcine singletons sla slc25a6 susflecks tags transducin wd40
Tagcloud (Intersection) ?