SFTPC and CXCL9

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SFTPC	CXCL9
Gene Name		surfactant protein C	chemokine (C-X-C motif) ligand 9
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Multivesicular Body Alveolar Lamellar Body	Extracellular Region Extracellular Space External Side Of Plasma Membrane
	Molecular Function	Protein Binding Protein Homodimerization Activity	Cytokine Activity Protein Binding Chemokine Activity CXCR3 Chemokine Receptor Binding
	Biological Process	Respiratory Gaseous Exchange Circadian Rhythm Response To Glucose Response To Lipopolysaccharide Response To Retinoic Acid Response To Vitamin A Protein Homooligomerization Response To Glucocorticoid Response To CAMP Response To Hyperoxia Response To Interleukin-6 Response To Growth Factor Cellular Response To Mechanical Stimulus Cellular Response To Nitric Oxide	Positive Regulation Of Leukocyte Chemotaxis Chemotaxis Defense Response Inflammatory Response Immune Response Cellular Defense Response Signal Transduction G-protein Coupled Receptor Signaling Pathway Cell-cell Signaling T Cell Chemotaxis Positive Regulation Of CAMP Metabolic Process Response To Lipopolysaccharide Regulation Of Cell Proliferation Positive Regulation Of CAMP-mediated Signaling Positive Regulation Of Myoblast Differentiation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Defense Response To Virus Chemokine-mediated Signaling Pathway Positive Regulation Of Myoblast Fusion
Pathways			Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS		Hypertriglyceridemia ( 23505323)
Protein-Protein Interactions		9 interactors: CXCL9 NEDD4 PQBP1 SEC22A SEC61G SYNE4 TMEM79 WWP1 WWP2	9 interactors: BMF CCDC155 CCR3 CXCR3 DPP4 PAX8 PTPN5 SFTPC SYNE4
Entrez ID		6440	4283
HPRD ID		01520	03416
Ensembl ID		ENSG00000168484	ENSG00000138755
Uniprot IDs		P11686	Q07325
PDB IDs		2YAD
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Interaction With Host Regulation Of Potassium Ion Transmembrane Transporter Activity Protein K63-linked Ubiquitination Regulation Of Potassium Ion Transmembrane Transport Viral Entry Into Host Cell Entry Into Host Cell Regulation Of Potassium Ion Transport Regulation Of Dendrite Morphogenesis Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Regulation Of Dendrite Development Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Locomotion Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Cuticle Development Protein Modification By Small Protein Conjugation Protein Catabolic Process Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Ion Transport Cornification Protein Polyubiquitination Cytoplasmic Transport Establishment Of Epithelial Cell Apical/basal Polarity Progesterone Receptor Signaling Pathway Viral Life Cycle Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Glucocorticoid Receptor Signaling Pathway Vesicle Fusion With Golgi Apparatus Cellular Macromolecule Catabolic Process Positive Regulation Of Intracellular Transport T Cell Chemotaxis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Establishment Of Monopolar Cell Polarity Proteasomal Protein Catabolic Process Establishment Of Localization In Cell Protein Targeting To Lysosome Regulation Of Membrane Potential Negative Regulation Of Sodium Ion Transport Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of CAMP-mediated Signaling Alternative MRNA Splicing, Via Spliceosome	Chemokine-mediated Signaling Pathway Chromosome Localization To Nuclear Envelope Involved In Synapsis Regulation Of Thyroid-stimulating Hormone Secretion Regulation Of Endothelial Cell Proliferation Pronephric Field Specification Negative Regulation Of Apoptotic Process Involved In Metanephric Collecting Duct Development Negative Regulation Of Apoptotic Process Involved In Metanephric Nephron Tubule Development Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephric Nephron Morphogenesis Positive Regulation Of Metanephric DCT Cell Differentiation Chemokine (C-C Motif) Ligand 11 Production Positive Regulation Of Angiogenesis Positive Regulation Of Thyroid Hormone Generation Kidney Rudiment Formation Thyroid-stimulating Hormone Signaling Pathway Metanephric Nephron Tubule Formation Positive Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Negative Regulation Of Extracellular Matrix Organization Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Nephron Morphogenesis Negative Regulation Of Extracellular Matrix Disassembly Positive Regulation Of Cytosolic Calcium Ion Concentration Metanephric Comma-shaped Body Morphogenesis Establishment Of Epithelial Cell Apical/basal Polarity Response To Cytokine Cytosolic Calcium Ion Homeostasis Metanephric Tubule Formation Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephros Development Metanephric S-shaped Body Morphogenesis Regulation Of Thyroid Hormone Generation Comma-shaped Body Morphogenesis Anoikis Establishment Of Apical/basal Cell Polarity Metanephric Distal Convoluted Tubule Development Metanephric Nephron Tubule Morphogenesis Polarized Epithelial Cell Differentiation Positive Regulation Of Cell Proliferation Regulation Of Angiogenesis Pronephros Development Negative Regulation Of Execution Phase Of Apoptosis Positive Regulation Of Protein Homooligomerization S-shaped Body Morphogenesis Positive Regulation Of Intracellular Transport T Cell Chemotaxis Metanephric Distal Tubule Development Regulation Of Cell-cell Adhesion Mediated By Integrin Chemokine Production Establishment Of Monopolar Cell Polarity Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation
Tagcloud ?		activating adenocarcinomas alveolar cdkn2a conditional deaths devastating embryogenesis epithelium foxm1 g12d ikbkb jnk jnk1 jun k kras lung myc nfkb1 nfkb2 oncogene pttg1 ras rela respiratory stimulates sufficient transgenic	academic assessing auc bacilli centre chemoattractant cxcl10 cxcl11 cxcr3 diagnosing differentiating gamma grades ifn immunoassays inducible ligands mig monokine pulmonary radiographic smear sputum surrogate tac tb tertiary usefulness
Tagcloud (Difference) ?		activating adenocarcinomas alveolar cdkn2a conditional deaths devastating embryogenesis epithelium foxm1 g12d ikbkb jnk jnk1 jun k kras lung myc nfkb1 nfkb2 oncogene pttg1 ras rela respiratory stimulates sufficient transgenic	academic assessing auc bacilli centre chemoattractant cxcl10 cxcl11 cxcr3 diagnosing differentiating gamma grades ifn immunoassays inducible ligands mig monokine pulmonary radiographic smear sputum surrogate tac tb tertiary usefulness
Tagcloud (Intersection) ?