SFTPC and PQBP1

Number of citations of the paper that reports this interaction (PMID 19366705)
5

Data Source:
BioGRID (pull down)

		SFTPC	PQBP1
Gene Name		surfactant protein C	polyglutamine binding protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Multivesicular Body Alveolar Lamellar Body	Nucleus Nucleoplasm Cytoplasm Cytoplasmic Stress Granule Nuclear Speck Neuronal Ribonucleoprotein Granule
	Molecular Function	Protein Binding Protein Homodimerization Activity	DNA Binding Transcription Coactivator Activity Ribonucleoprotein Complex Binding
	Biological Process	Respiratory Gaseous Exchange Circadian Rhythm Response To Glucose Response To Lipopolysaccharide Response To Retinoic Acid Response To Vitamin A Protein Homooligomerization Response To Glucocorticoid Response To CAMP Response To Hyperoxia Response To Interleukin-6 Response To Growth Factor Cellular Response To Mechanical Stimulus Cellular Response To Nitric Oxide	Alternative MRNA Splicing, Via Spliceosome Transcription, DNA-templated Regulation Of Transcription, DNA-templated Neuron Projection Development Regulation Of RNA Splicing Regulation Of Dendrite Morphogenesis
Pathways
Drugs
Diseases
GWAS		Hypertriglyceridemia ( 23505323)
Protein-Protein Interactions		9 interactors: CXCL9 NEDD4 PQBP1 SEC22A SEC61G SYNE4 TMEM79 WWP1 WWP2	23 interactors: APBB1 APP AQR ATXN1 C14orf1 CLTB EEF1A1 GOLGA2 HNRNPH2 LNX1 LRIF1 LZTS2 MAPRE1 MED31 POLR2A POU3F2 RAB8A RCVRN SFTPC TLX3 TXNL4A WBP11 WDR77
Entrez ID		6440	10084
HPRD ID		01520	02354
Ensembl ID		ENSG00000168484	ENSG00000102103
Uniprot IDs		P11686	O60828
PDB IDs		2YAD
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Interaction With Host Regulation Of Potassium Ion Transmembrane Transporter Activity Protein K63-linked Ubiquitination Regulation Of Potassium Ion Transmembrane Transport Viral Entry Into Host Cell Entry Into Host Cell Regulation Of Potassium Ion Transport Regulation Of Dendrite Morphogenesis Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Regulation Of Dendrite Development Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Locomotion Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Cuticle Development Protein Modification By Small Protein Conjugation Protein Catabolic Process Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Ion Transport Cornification Protein Polyubiquitination Cytoplasmic Transport Establishment Of Epithelial Cell Apical/basal Polarity Progesterone Receptor Signaling Pathway Viral Life Cycle Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Glucocorticoid Receptor Signaling Pathway Vesicle Fusion With Golgi Apparatus Cellular Macromolecule Catabolic Process Positive Regulation Of Intracellular Transport T Cell Chemotaxis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Establishment Of Monopolar Cell Polarity Proteasomal Protein Catabolic Process Establishment Of Localization In Cell Protein Targeting To Lysosome Regulation Of Membrane Potential Negative Regulation Of Sodium Ion Transport Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of CAMP-mediated Signaling Alternative MRNA Splicing, Via Spliceosome	RNA Processing MRNA Processing MRNA Metabolic Process RNA Splicing RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression Visual Learning Visual Behavior Associative Learning Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Component Assembly Response To Light Stimulus Learning Regulation Of Protein Binding Nitrogen Compound Metabolic Process Mitotic Cell Cycle Cell Division Response To Radiation Negative Regulation Of Neuron Differentiation Negative Regulation Of Thymidylate Synthase Biosynthetic Process Respiratory Gaseous Exchange Cell Cycle Regulation Of Neuron Differentiation Regulation Of Binding Learning Or Memory Neurohypophysis Development Synaptic Growth At Neuromuscular Junction Transcription, RNA-templated Cell Cycle Process Negative Regulation Of Neurogenesis Cognition Positive Regulation Of Microtubule Plus-end Binding Collateral Sprouting In Absence Of Injury Golgi Vesicle Fusion To Target Membrane Regulation Of Nitrogen Compound Metabolic Process Mitotic Nuclear Division Response To Abiotic Stimulus Positive Regulation Of Cellular Biosynthetic Process Ribonucleoprotein Complex Biogenesis Mitotic Cell Cycle Process Neuron Differentiation Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Development Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Regulation Of Nucleic Acid-templated Transcription
Tagcloud ?		activating adenocarcinomas alveolar cdkn2a conditional deaths devastating embryogenesis epithelium foxm1 g12d ikbkb jnk jnk1 jun k kras lung myc nfkb1 nfkb2 oncogene pttg1 ras rela respiratory stimulates sufficient transgenic	amygdala causative cleaved cognition confirming correspondingly dark declined declines efficiently endogenously exploration kd knock maze object obvious ordinary phenylbutyric polyglutamine possessed prefrontal repetitive rescued retardation suppressing syndromic transgene underlie
Tagcloud (Difference) ?		activating adenocarcinomas alveolar cdkn2a conditional deaths devastating embryogenesis epithelium foxm1 g12d ikbkb jnk jnk1 jun k kras lung myc nfkb1 nfkb2 oncogene pttg1 ras rela respiratory stimulates sufficient transgenic	amygdala causative cleaved cognition confirming correspondingly dark declined declines efficiently endogenously exploration kd knock maze object obvious ordinary phenylbutyric polyglutamine possessed prefrontal repetitive rescued retardation suppressing syndromic transgene underlie
Tagcloud (Intersection) ?