CXCL9 and BTNL9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CXCL9	BTNL9
Description		C-X-C motif chemokine ligand 9	butyrophilin like 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space External Side Of Plasma Membrane	Plasma Membrane External Side Of Plasma Membrane Membrane
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity CXCR Chemokine Receptor Binding CXCR3 Chemokine Receptor Binding	Signaling Receptor Binding Protein Binding
	Biological Process	Chemotaxis Defense Response Inflammatory Response Immune Response Cellular Defense Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Response To Bacterium Neutrophil Chemotaxis Killing Of Cells Of Another Organism Regulation Of Cell Population Proliferation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Positive Regulation Of Myoblast Fusion	Regulation Of Cytokine Production T Cell Receptor Signaling Pathway
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Butyrophilin (BTN) family interactions
Drugs
Diseases
GWAS		Hippocampal volume ( 29274321) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)	Metabolite levels ( 23823483)
Interacting Genes		76 interacting genes: AMIGO1 AQP6 ATP1B4 BMF BSCL2 BTNL9 C16orf92 CCL11 CCL13 CCL2 CCL21 CCL26 CCL28 CCL5 CCR3 CD33 CHODL CLDN2 CLDN5 CLDN7 CLEC17A CLEC2D CLEC4E CLEC7A CXCL10 CXCL11 CXCL12 CXCL14 CXCL17 CXCL2 CXCR3 DPP4 EPGN EREG FBXO7 FCGR2A FFAR2 FNDC9 FUT7 GJB1 GORAB GPR42 IFNGR2 ITM2C KASH5 KIR2DL3 LDLRAD1 LEUTX LRRC25 LSMEM2 MR1 MTIF3 MUC1 NEMP1 PAX8 PF4 PPBP PTPN5 RHCG SFTPC SLC10A1 SLC39A1 SSMEM1 SUSD3 SYNE4 TM4SF18 TMED5 TMEM106C TMEM234 TMEM237 TMEM31 TMPRSS2 TNFSF14 TNFSF8 TSPAN18 XCL1	16 interacting genes: ADAM33 ADIPOQ CXCL9 CYB5B EDDM3A GIMAP5 JAGN1 NINJ2 PLPP6 RPRM SLC38A7 SLC61A1 SMIM3 SYS1 TNF UPK2
Entrez ID		4283	153579
HPRD ID		03416	12550
Ensembl ID		ENSG00000138755	ENSG00000165810
Uniprot IDs		Q07325	A0A1S5UZ21 Q6UXG8 Q8N324
PDB IDs
Enriched GO Terms of Interacting Partners?		Chemokine Activity Cell Chemotaxis Leukocyte Chemotaxis Chemotaxis Locomotion Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Leukocyte Migration Cytokine Activity Antimicrobial Humoral Response Chemokine-mediated Signaling Pathway Mononuclear Cell Migration Granulocyte Chemotaxis Inflammatory Response Granulocyte Migration Killing Of Cells Of Another Organism Immune Response Immune System Process Humoral Immune Response Myeloid Leukocyte Migration Defense Response Cell Killing Lymphocyte Migration T Cell Migration Lymphocyte Chemotaxis CCR Chemokine Receptor Binding Cell Migration T Cell Chemotaxis Eosinophil Chemotaxis Cytokine-mediated Signaling Pathway Regulation Of Leukocyte Migration Eosinophil Migration Chemokine Receptor Binding Defense Response To Symbiont Cell Motility Defense Response To Other Organism Positive Regulation Of Chemotaxis Regulation Of Lymphocyte Chemotaxis CXCR Chemokine Receptor Binding Regulation Of Chemotaxis Regulation Of T Cell Chemotaxis Response To Other Organism Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Mononuclear Cell Migration Protein Binding Positive Regulation Of T Cell Migration Positive Regulation Of Leukocyte Migration Regulation Of Lymphocyte Migration Positive Regulation Of Lymphocyte Migration Regulation Of Immune System Process G Protein-coupled Receptor Signaling Pathway	Positive Regulation Of Neutrophil Activation Regulation Of Neutrophil Activation Cytokine-mediated Signaling Pathway Membrane Negative Regulation Of Bile Acid Secretion Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Translational Initiation By Iron Positive Regulation Of Interleukin-33 Production Protein Localization To Plasma Membrane Response To Gram-negative Bacterium Negative Regulation Of Secretion Negative Regulation Of Branching Involved In Lung Morphogenesis Response To Monosaccharide Response To Carbohydrate Negative Regulation Of Blood Pressure Negative Regulation Of Metanephric Mesenchymal Cell Migration Positive Regulation Of Renal Albumin Absorption Positive Regulation Of Metanephric Podocyte Development Positive Regulation Of Glycogen (starch) Synthase Activity Sperm Displacement L-asparagine:sodium Symporter Activity L-glutamine:sodium Symporter Activity Molybdate Ion Transmembrane Transporter Activity Molybdate Ion Transport Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process Cytokine Activity Leukocyte Migration Neutrophil Migration Regulation Of Hormone Secretion Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of MAP Kinase Activity Protein Localization To Cell Periphery Chronic Inflammatory Response To Antigenic Stimulus Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Chronic Inflammatory Response To Antigenic Stimulus Negative Regulation Of L-glutamate Import Across Plasma Membrane Positive Regulation Of Interleukin-8 Production Positive Regulation Of Fractalkine Production Positive Regulation Of Blood Microparticle Formation Response To Gold Nanoparticle Regulation Of D-glucose Import Positive Regulation Of Vitamin D Biosynthetic Process Negative Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Detection Of Oxidative Stress Negative Regulation Of Hormone Secretion Positive Regulation Of Chemokine Production Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Response To Other Organism
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