CXCL9 and BMF

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CXCL9	BMF
Gene Name		chemokine (C-X-C motif) ligand 9	Bcl2 modifying factor
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space External Side Of Plasma Membrane	Acrosomal Vesicle Mitochondrial Outer Membrane Cytosol Plasma Membrane Myosin Complex
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity CXCR3 Chemokine Receptor Binding	Protein Binding
	Biological Process	Positive Regulation Of Leukocyte Chemotaxis Chemotaxis Defense Response Inflammatory Response Immune Response Cellular Defense Response Signal Transduction G-protein Coupled Receptor Signaling Pathway Cell-cell Signaling T Cell Chemotaxis Positive Regulation Of CAMP Metabolic Process Response To Lipopolysaccharide Regulation Of Cell Proliferation Positive Regulation Of CAMP-mediated Signaling Positive Regulation Of Myoblast Differentiation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Defense Response To Virus Chemokine-mediated Signaling Pathway Positive Regulation Of Myoblast Fusion	Apoptotic Process Positive Regulation Of Protein Homooligomerization Anoikis Positive Regulation Of Release Of Cytochrome C From Mitochondria Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Negative Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Programmed Cell Death Activation of BH3-only proteins BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members Activation of BMF and translocation to mitochondria Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS			Dehydroepiandrosterone sulphate levels ( 21533175) Ewing sarcoma ( 22327514)
Protein-Protein Interactions		9 interactors: BMF CCDC155 CCR3 CXCR3 DPP4 PAX8 PTPN5 SFTPC SYNE4	15 interactors: BCL2 BCL2A1 BCL2L1 BCL2L2 CXCL9 DYNLL1 DYNLL2 MAPK8 MCL1 MYO5A NNMT REL SEC14L4 TCF12 TFIP11
Entrez ID		4283	90427
HPRD ID		03416	05881
Ensembl ID		ENSG00000138755	ENSG00000104081
Uniprot IDs		Q07325	Q96LC9
PDB IDs
Enriched GO Terms of Interacting Partners?		Chemokine-mediated Signaling Pathway Chromosome Localization To Nuclear Envelope Involved In Synapsis Regulation Of Thyroid-stimulating Hormone Secretion Regulation Of Endothelial Cell Proliferation Pronephric Field Specification Negative Regulation Of Apoptotic Process Involved In Metanephric Collecting Duct Development Negative Regulation Of Apoptotic Process Involved In Metanephric Nephron Tubule Development Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephric Nephron Morphogenesis Positive Regulation Of Metanephric DCT Cell Differentiation Chemokine (C-C Motif) Ligand 11 Production Positive Regulation Of Angiogenesis Positive Regulation Of Thyroid Hormone Generation Kidney Rudiment Formation Thyroid-stimulating Hormone Signaling Pathway Metanephric Nephron Tubule Formation Positive Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Negative Regulation Of Extracellular Matrix Organization Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Nephron Morphogenesis Negative Regulation Of Extracellular Matrix Disassembly Positive Regulation Of Cytosolic Calcium Ion Concentration Metanephric Comma-shaped Body Morphogenesis Establishment Of Epithelial Cell Apical/basal Polarity Response To Cytokine Cytosolic Calcium Ion Homeostasis Metanephric Tubule Formation Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephros Development Metanephric S-shaped Body Morphogenesis Regulation Of Thyroid Hormone Generation Comma-shaped Body Morphogenesis Anoikis Establishment Of Apical/basal Cell Polarity Metanephric Distal Convoluted Tubule Development Metanephric Nephron Tubule Morphogenesis Polarized Epithelial Cell Differentiation Positive Regulation Of Cell Proliferation Regulation Of Angiogenesis Pronephros Development Negative Regulation Of Execution Phase Of Apoptosis Positive Regulation Of Protein Homooligomerization S-shaped Body Morphogenesis Positive Regulation Of Intracellular Transport T Cell Chemotaxis Metanephric Distal Tubule Development Regulation Of Cell-cell Adhesion Mediated By Integrin Chemokine Production Establishment Of Monopolar Cell Polarity Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation	Intrinsic Apoptotic Signaling Pathway Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrion Organization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Apoptotic Process Positive Regulation Of Mitochondrion Organization Regulation Of Signal Transduction Programmed Cell Death Cell Death Death Regulation Of Cell Death Negative Regulation Of Anoikis Regulation Of Signaling Regulation Of Anoikis Positive Regulation Of Intracellular Transport Positive Regulation Of Signal Transduction Intracellular Signal Transduction Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Cell Death Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Intracellular Signal Transduction Negative Regulation Of Intracellular Signal Transduction Regulation Of Intracellular Transport Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Apoptotic Mitochondrial Changes Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Immune System Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Cellular Localization Regulation Of Neuron Death Cellular Response To Stimulus Regulation Of Establishment Of Protein Localization Response To Stimulus Response To Organic Substance Response To Cytokine Melanin Metabolic Process Positive Regulation Of Transport
Tagcloud ?		academic assessing auc bacilli centre chemoattractant cxcl10 cxcl11 cxcr3 diagnosing differentiating gamma grades ifn immunoassays inducible ligands mig monokine pulmonary radiographic smear sputum surrogate tac tb tertiary usefulness	70z bcgf begin bpa call chromatographic die discrete etc glycoproteins glycosylated hcgf helper heterogeneously ig implying lymphokine lymphokines mcgf mildly permeation psf purifies purify splenic supernatants synthesize variously wehi
Tagcloud (Difference) ?		academic assessing auc bacilli centre chemoattractant cxcl10 cxcl11 cxcr3 diagnosing differentiating gamma grades ifn immunoassays inducible ligands mig monokine pulmonary radiographic smear sputum surrogate tac tb tertiary usefulness	70z bcgf begin bpa call chromatographic die discrete etc glycoproteins glycosylated hcgf helper heterogeneously ig implying lymphokine lymphokines mcgf mildly permeation psf purifies purify splenic supernatants synthesize variously wehi
Tagcloud (Intersection) ?