CXCL9 and MR1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CXCL9	MR1
Description		C-X-C motif chemokine ligand 9	major histocompatibility complex, class I-related
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space External Side Of Plasma Membrane	Golgi Membrane Extracellular Region Extracellular Space Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane External Side Of Plasma Membrane Membrane Early Endosome Membrane Late Endosome Membrane MHC Class I Protein Complex
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity CXCR Chemokine Receptor Binding CXCR3 Chemokine Receptor Binding	Protein Binding Beta-2-microglobulin Binding MHC Class I Receptor Activity T Cell Receptor Binding
	Biological Process	Chemotaxis Defense Response Inflammatory Response Immune Response Cellular Defense Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Response To Bacterium Neutrophil Chemotaxis Killing Of Cells Of Another Organism Regulation Of Cell Population Proliferation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Positive Regulation Of Myoblast Fusion	Immune System Process Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Regulation Of T Cell Mediated Immunity Positive Regulation Of T Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Immune Response Antigen Processing And Presentation Of Exogenous Antigen T Cell Differentiation In Thymus Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs			Antithymocyte immunoglobulin (rabbit)
Diseases
GWAS		Hippocampal volume ( 29274321) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Post bronchodilator FEV1 ( 26634245) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		76 interacting genes: AMIGO1 AQP6 ATP1B4 BMF BSCL2 BTNL9 C16orf92 CCL11 CCL13 CCL2 CCL21 CCL26 CCL28 CCL5 CCR3 CD33 CHODL CLDN2 CLDN5 CLDN7 CLEC17A CLEC2D CLEC4E CLEC7A CXCL10 CXCL11 CXCL12 CXCL14 CXCL17 CXCL2 CXCR3 DPP4 EPGN EREG FBXO7 FCGR2A FFAR2 FNDC9 FUT7 GJB1 GORAB GPR42 IFNGR2 ITM2C KASH5 KIR2DL3 LDLRAD1 LEUTX LRRC25 LSMEM2 MR1 MTIF3 MUC1 NEMP1 PAX8 PF4 PPBP PTPN5 RHCG SFTPC SLC10A1 SLC39A1 SSMEM1 SUSD3 SYNE4 TM4SF18 TMED5 TMEM106C TMEM234 TMEM237 TMEM31 TMPRSS2 TNFSF14 TNFSF8 TSPAN18 XCL1	7 interacting genes: CDS2 CXCL9 EMP3 ERMP1 FATE1 GALNT15 NINJ2
Entrez ID		4283	3140
HPRD ID		03416	09012
Ensembl ID		ENSG00000138755	ENSG00000153029
Uniprot IDs		Q07325	A0A8C8PVM5 Q95460
PDB IDs			4GUP 4L4T 4L4V 4LCW 4NQC 4NQD 4NQE 4PJ5 4PJ7 4PJ8 4PJ9 4PJA 4PJB 4PJC 4PJD 4PJE 4PJF 4PJG 4PJH 4PJI 4PJX 5D5M 5D7I 5D7J 5D7L 5U16 5U17 5U1R 5U2V 5U6Q 5U72 6MWR 6PUC 6PUD 6PUE 6PUF 6PUG 6PUH 6PUI 6PUJ 6PUK 6PUL 6PUM 6PVC 6PVD 6W9U 6W9V 6XQP 7LLI 7LLJ 7RNO 7UFJ 7UMG 7ZT2 7ZT3 7ZT4 7ZT5 7ZT7 7ZT8 7ZT9 8BP6 8Y6X 9BTX 9BTY 9BTZ 9BU0 9CGR 9CGS
Enriched GO Terms of Interacting Partners?		Chemokine Activity Cell Chemotaxis Leukocyte Chemotaxis Chemotaxis Locomotion Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Leukocyte Migration Cytokine Activity Antimicrobial Humoral Response Chemokine-mediated Signaling Pathway Mononuclear Cell Migration Granulocyte Chemotaxis Inflammatory Response Granulocyte Migration Killing Of Cells Of Another Organism Immune Response Immune System Process Humoral Immune Response Myeloid Leukocyte Migration Defense Response Cell Killing Lymphocyte Migration T Cell Migration Lymphocyte Chemotaxis CCR Chemokine Receptor Binding Cell Migration T Cell Chemotaxis Eosinophil Chemotaxis Cytokine-mediated Signaling Pathway Regulation Of Leukocyte Migration Eosinophil Migration Chemokine Receptor Binding Defense Response To Symbiont Cell Motility Defense Response To Other Organism Positive Regulation Of Chemotaxis Regulation Of Lymphocyte Chemotaxis CXCR Chemokine Receptor Binding Regulation Of Chemotaxis Regulation Of T Cell Chemotaxis Response To Other Organism Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Mononuclear Cell Migration Protein Binding Positive Regulation Of T Cell Migration Positive Regulation Of Leukocyte Migration Regulation Of Lymphocyte Migration Positive Regulation Of Lymphocyte Migration Regulation Of Immune System Process G Protein-coupled Receptor Signaling Pathway
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