LARP6 and MIR141

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		LARP6	MIR141
Description		La ribonucleoprotein 6, translational regulator	microRNA 141
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Ribonucleoprotein Complex	Extracellular Space RISC Complex
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Myosin Binding RNA Stem-loop Binding MRNA 5'-UTR Binding Sequence-specific MRNA Binding	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	RNA Processing Regulation Of Translation Positive Regulation Of Collagen Biosynthetic Process	Positive Regulation Of Cell Population Proliferation MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Notch Signaling Pathway Negative Regulation Of Inflammatory Response Negative Regulation Of Transformation Of Host Cell By Virus Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Pathways
Drugs
Diseases
GWAS		Insulin-related traits (multivariate analysis) ( 32002517) Proinsulin levels ( 21873549)
Interacting Genes		5 interacting genes: ADARB1 APP CRYAA MIR141 MIR145	87 interacting genes: ADARB1 APOBEC3B C1QBP CPSF7 DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 EDC4 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FAM98B FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP6 LARP7 LIN28A LRPPRC MARS1 MATR3 MSI2 MYEF2 NONO NUDT16L1 NUDT21 P3H1 PDCD11 PGAM5 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 QARS1 QKI RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYNCRIP TAF15 TENT2 TRA2B TRMT1L UPF1 UTP20 YBX1 YBX2 YBX3 ZC3H11A ZNF346
Entrez ID		55323	406933
HPRD ID		10966
Ensembl ID		ENSG00000166173	ENSG00000207708
Uniprot IDs		Q9BRS8
PDB IDs		2MTF 2MTG
Enriched GO Terms of Interacting Partners?		Hypoglossal Nerve Morphogenesis Negative Regulation Of Metabolic Process Muscle Tissue Morphogenesis Negative Regulation Of Macromolecule Metabolic Process Anatomical Structure Morphogenesis Regulation Of Protein Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Translation Negative Regulation Of Gene Expression Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Inflammatory Response MiRNA-mediated Gene Silencing By Inhibition Of Translation RISC Complex MRNA Base-pairing Post-transcriptional Repressor Activity Negative Regulation Of Somatic Stem Cell Division Negative Regulation Of Interleukin-16 Production Negative Regulation Of Cell Population Proliferation Regulation Of Cell Population Proliferation Axonogenesis Spinal Cord Ventral Commissure Morphogenesis Facial Nerve Morphogenesis Negative Regulation Of Protein Metabolic Process Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Post-transcriptional Regulation Of Gene Expression Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization MRNA 3'-UTR Binding Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Negative Regulation Of Transformation Of Host Cell By Virus Post-transcriptional Gene Silencing MiRNA-mediated Post-transcriptional Gene Silencing Regulation Of Transformation Of Host Cell By Virus Positive Regulation Of Cardiac Vascular Smooth Muscle Cell Differentiation Negative Regulation Of Vascular Associated Smooth Muscle Cell Dedifferentiation Establishment Or Maintenance Of Cell Type Involved In Phenotypic Switching Apoptotic Process Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Double-stranded RNA Adenosine Deaminase Activity	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing Nucleic Acid Metabolic Process MRNA Processing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Binding Macromolecule Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Nucleus Regulation Of MRNA Metabolic Process Post-transcriptional Regulation Of Gene Expression Catalytic Step 2 Spliceosome Ribonucleoprotein Complex Spliceosomal Complex Nucleoplasm Negative Regulation Of MRNA Metabolic Process Regulation Of Translation Negative Regulation Of RNA Catabolic Process MiRNA Binding Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Aminoacyl-tRNA Synthetase Multienzyme Complex Cytoplasmic Stress Granule MRNA 3'-UTR Binding Negative Regulation Of MRNA Catabolic Process RNA Stabilization MRNA Stabilization Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Translation TRNA Metabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity MRNA 5'-UTR Binding Regulation Of Macromolecule Metabolic Process TRNA Aminoacylation Positive Regulation Of Gene Expression Regulation Of MRNA Stability RNA Transport Positive Regulation Of Cytoplasmic Translation Regulation Of Primary Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Ligase Activity
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