SNRPD1 and U2AF1

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid)

		SNRPD1	U2AF1
Description		small nuclear ribonucleoprotein D1 polypeptide	U2 small nuclear RNA auxiliary factor 1
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GO Annotations	Cellular Component	Commitment Complex Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U2-type Spliceosomal Complex U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytoplasm Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal Tri-snRNP Complex Ribonucleoprotein Complex	Nucleus Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck Catalytic Step 2 Spliceosome U2AF Complex
	Molecular Function	RNA Binding Protein Binding U1 SnRNP Binding	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding RS Domain Binding
	Biological Process	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Processing MRNA Processing RNA Splicing 7-methylguanosine Cap Hypermethylation U2-type Prespliceosome Assembly	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways		snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway SARS-CoV-2 modulates host translation machinery	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)	Blood and toenail selenium levels ( 25343990)
Interacting Genes		19 interacting genes: CEBPA CLNS1A DDX20 ERCC6 FOXP1 GEMIN2 GEMIN4 GEMIN5 IL7R LSM8 PRMT5 PTEN SMN1 SMN2 SNRPB SNRPD2 SREK1 U2AF1 WDR77	58 interacting genes: ALG13 AP1B1 AP2B1 CARNMT1 CHERP CIRSR CLK2 CPEB2 DHX38 EFHC2 EPB41 FILNC1 FRA10AC1 HINFP HMGB2 HNRNPK HNRNPM IL7R JMJD6 KRT1 KRT75 MAP1B MEOX2 MFAP1 MLH1 NDN NKAP NXF1 PABPC1 PRPF19 PRPF38A PRPF4 PRPF40A PTEN RBM10 RNPS1 RP9 SF3A3 SF3B2 SNRNP35 SNRPD1 SRPK1 SRPK2 SRRM4 SRSF1 SRSF2 SRSF3 SUV39H1 TOE1 TRA2B U2AF2 VEGFA VPS26C WEE2-AS1 ZCCHC10 ZNF417 ZRANB2 ZRSR2
Entrez ID		6632	7307
HPRD ID		03040	01871
Ensembl ID		ENSG00000167088	ENSG00000160201
Uniprot IDs		P62314	Q01081 Q7Z780
PDB IDs		1B34 3CW1 3JCR 3PGW 4F7U 4PJO 4V98 4WZJ 5MQF 5O9Z 5XJC 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6Y53 6Y5Q 7A5P 7ABG 7ABI 7B0Y 7DVQ 7EVO 7QTT 7VPX 7W59 7W5A 7W5B 8C6J 8CH6 8H6E 8H6J 8H6K 8H6L 8HK1 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 8Q7Q 8Q7V 8Q7W 8Q7X 8Q91 8QO9 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8R7N 8RC0 8RM5 8RO2 8Y6O 8Y7E 9E3B 9E3C 9FMD 9GBW 9GC0 9GCL	1JMT
Enriched GO Terms of Interacting Partners?		Spliceosomal SnRNP Assembly SMN-Sm Protein Complex Protein-RNA Complex Assembly RNA Splicing SMN Complex Gemini Of Cajal Bodies MRNA Processing RNA Metabolic Process MRNA Metabolic Process RNA Splicing, Via Transesterification Reactions Nucleoplasm Methylosome RNA Processing Nucleic Acid Metabolic Process Spliceosomal Complex Nucleobase-containing Compound Metabolic Process Spliceosomal Complex Assembly Macromolecule Metabolic Process Protein-containing Complex Assembly Protein-containing Complex Organization MRNA Splicing, Via Spliceosome Nuclear Body Nucleus Small Nuclear Ribonucleoprotein Complex Cajal Body Cellular Component Assembly DNA-templated Transcription Termination Positive Regulation Of MRNA Splicing, Via Spliceosome U4/U6 X U5 Tri-snRNP Complex RNA Binding Positive Regulation Of RNA Splicing PICln-Sm Protein Complex U2-type Precatalytic Spliceosome 7-methylguanosine Cap Hypermethylation Endothelial Cell Activation U4 SnRNP Regulation Of Cell Size Catalytic Step 2 Spliceosome U1 SnRNP Precatalytic Spliceosome Positive Regulation Of Gene Expression U5 SnRNP Regulation Of MRNA Splicing, Via Spliceosome Macromolecule Methylation U2-type Prespliceosome Assembly U12-type Spliceosomal Complex U2 SnRNP Methyl-CpG Binding Regulation Of MRNA Processing U2-type Spliceosomal Complex	RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Spliceosomal Complex Regulation Of MRNA Splicing, Via Spliceosome RNA Binding Nucleic Acid Metabolic Process Regulation Of MRNA Processing Regulation Of RNA Splicing Nuclear Speck Nucleic Acid Binding Nucleobase-containing Compound Metabolic Process Spliceosomal Complex Assembly Regulation Of MRNA Metabolic Process Catalytic Step 2 Spliceosome Nucleus Nucleoplasm Protein-RNA Complex Assembly Macromolecule Metabolic Process MRNA Binding U2-type Precatalytic Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Metabolic Process U12-type Spliceosomal Complex Negative Regulation Of RNA Splicing U2-type Spliceosomal Complex Positive Regulation Of RNA Splicing Precatalytic Spliceosome U1 SnRNP Negative Regulation Of Nucleobase-containing Compound Metabolic Process Ribonucleoprotein Complex Negative Regulation Of RNA Metabolic Process Protein-containing Complex Assembly U2-type Prespliceosome Assembly Regulation Of Nucleobase-containing Compound Metabolic Process U2 SnRNP Commitment Complex Positive Regulation Of Viral Genome Replication Pre-mRNA 3'-splice Site Binding U2AF Complex MRNA Splice Site Recognition Regulation Of RNA Metabolic Process Protein-containing Complex Organization MRNA 5'-splice Site Recognition T Cell Differentiation In Thymus
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