SH3GLB2 and KRTAP4-5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SH3GLB2	KRTAP4-5
Description		SH3 domain containing GRB2 like, endophilin B2	keratin associated protein 4-5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Membrane	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Protein Binding Identical Protein Binding Cadherin Binding	Protein Binding
	Biological Process	Membrane Organization	Hair Cycle
Pathways			Keratinization
Drugs
Diseases
GWAS		Blood metabolite levels ( 26401656) Serum metabolite concentrations in chronic kidney disease ( 33838163)
Interacting Genes		39 interacting genes: CCDC158 CCND3 CDKN2D CNOT7 EFHC1 EXOSC1 EXOSC5 FHL3 FXR1 GAA GADD45G GIT2 GOLGA2 KDM1A KRTAP10-1 KRTAP10-8 KRTAP4-5 KRTAP5-11 KRTAP9-3 LGALS14 LNX2 LSM3 MAGEA1 MORF4L1 NMI NTAQ1 NXF1 OGT PICK1 RSPH1 SH3GLB1 SH3KBP1 SREK1 STX4 TBC1D7 TEX11 TRAF1 TSG101 YES1	74 interacting genes: AXIN2 BAG4 CRCT1 CREB5 CYSRT1 FAM76B FBXO34 GATA1 GLRX3 HOXA1 KPRP KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP13-2 KRTAP4-2 KRTAP4-4 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-1 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 MEOX2 NBPF19 NOTCH2NLA NUFIP2 OTX1 PEAR1 POTEB3 POU4F2 PRKAB2 RORB SH3GLB2 SHFL SLC4A7 SMCP TRIM42 TSPAN4 VASN YY1 ZNF552 ZNF774 ZNF835 ZNF837
Entrez ID		56904	85289
HPRD ID		15334	13946
Ensembl ID		ENSG00000148341	ENSG00000198271
Uniprot IDs		B7ZC38 B7ZC39 Q9NR46	Q9BYR2
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Exonuclease Activity Cytosol Intermediate Filament Autophagic Cell Death Keratin Filament Cell Death Programmed Cell Death Nucleolar Exosome (RNase Complex)	Intermediate Filament Keratinization Epidermis Development Keratin Filament Tissue Development Identical Protein Binding Protein Binding
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