MTERF4 and CRYAA

Number of citations of the paper that reports this interaction (PubMedID 24453475)
30

Data Source:
BioGRID (pull down)

		MTERF4	CRYAA
Description		mitochondrial transcription termination factor 4	crystallin alpha A
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Cytosol	Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding RRNA Binding	Structural Molecule Activity Structural Constituent Of Eye Lens Protein Binding Identical Protein Binding Metal Ion Binding Unfolded Protein Binding
	Biological Process	RRNA Processing Mitochondrial Transcription Protein Targeting To Mitochondrion Heart Development Ribosome Assembly Camera-type Eye Development Mitochondrial Ribosome Assembly Regulation Of Mitochondrial Transcription	Response To Hypoxia Lens Development In Camera-type Eye Lens Morphogenesis In Camera-type Eye Apoptotic Process Mitochondrion Organization Actin Filament Organization Microtubule-based Process Tubulin Complex Assembly Visual Perception Response To Heat Negative Regulation Of Gene Expression Positive Regulation Of Cell Growth Negative Regulation Of Intracellular Transport Protein Refolding Response To Hydrogen Peroxide Camera-type Eye Development Negative Regulation Of Apoptotic Process Embryonic Camera-type Eye Morphogenesis Protein Stabilization Apoptotic Process Involved In Morphogenesis Response To UV-A Lens Fiber Cell Morphogenesis
Pathways		rRNA modification in the mitochondrion
Drugs
Diseases
GWAS			Age-related nuclear cataracts ( 24951543 33311586) Diastolic blood pressure ( 27618452 27841878 28135244 28739976) Metabolite levels ( 23823483) Systolic blood pressure ( 27618452 27841878 28739976)
Interacting Genes		11 interacting genes: APP ATXN1 BANP CIDEB CRYAA DGAT2L6 EMD FOS OSGIN1 TNFRSF10D UBC	134 interacting genes: - ADPRHL1 AKT3 ALB ALDH1L2 ANKRD44 APPL2 ARFGAP1 ARMCX4 ARRDC1-AS1 ATG16L1 BCL2L1 BORA BTRC CAMKK2 CD209 CDC40 CEBPZ CENPH CER1 CNOT8 COPB2 CRTAC1 CRYAB CRYBA1 CRYBB2 CRYGC CRYGD CRYZ CS CSTF2T DCAF11 DCAF8 DCK DDX3X DUS4L E2F7 EEPD1 ETFB EYA4 FAM131B FAM131C FAM182A FASN GIGYF2 GLYATL1 GNAI2 GORASP2 GSTZ1 HABP4 HCLS1 HSPB1 HSPB2 IGHG1 IGKV1-5 JKAMP KBTBD12 KIZ KNG1 LALBA LARP6 LIMA1 MAP3K7CL MAPKBP1 MCM7 MCRS1 MINDY1 MIP MPHOSPH6 MTERF4 MYO5C NAT9 NCF4 NTAQ1 NUP43 OSBPL3 OTOGL OTULIN PABIR2 PAFAH1B1 PCYT2 PHC1 PLAUR PMS2 PRM2 PSMB6 PTPN2 PTTG2 QRICH1 RAB24 RAB29 RAB3C RAB40B RAB43 RAD51 RBBP7 RNASEH1 RNGTT RPS6KA5 SDCBP SEC24C SEH1L SESN2 SGCD SLC20A1 SLC25A25 SLC25A26 SLC25A28 SPG21 SSBP4 SULF1 SYK TASL TEAD4 TFDP1 TGOLN2 TLE4 TMEM254 TMEM52B TSR3 TTC27 TTC39B TUBAL3 TUBGCP5 UBR2 UPP1 WDR55 WDR83 WIPI2 WWC2 ZIM2 ZNF3 ZNF639 ZSCAN20
Entrez ID		130916	1409
HPRD ID		14699	00427
Ensembl ID		ENSG00000122085	ENSG00000160202
Uniprot IDs		B4DFP7 Q7Z6M4	A0A8C8KJZ9 P02489
PDB IDs		4FP9 4FZV 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF3 7OF5 7OF7 7OIC 7PD3 8PK0 8QSJ	6T1R
Enriched GO Terms of Interacting Partners?		Response To Light Stimulus Associative Learning Memory Learning Response To Radiation Amyloid Fibril Formation Amyloid-beta Complex Growth Cone Lamellipodium Visual Behavior Regulation Of Response To Calcium Ion Learning Or Memory Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Response To Growth Factor Stimulus Visual Learning Identical Protein Binding TMEM240-body Skeletal Muscle Cell Differentiation Medium-term Memory Cellular Response To Prolactin Acetylcholine Receptor Activator Activity PTB Domain Binding Apoptotic Process Cognition Adult Locomotory Behavior Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Response To Growth Factor Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle System Process Endoplasmic Reticulum Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Nervous System Process Response To Prolactin Conditioned Taste Aversion Acylglycerol Acyl-chain Remodeling Programmed Cell Death Cell Death Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus	Structural Constituent Of Eye Lens Lens Development In Camera-type Eye
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