MTERF4 and CIDEB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MTERF4	CIDEB
Description		mitochondrial transcription termination factor 4	cell death inducing DFFA like effector b
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Cytosol	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Cytosol Membrane COPII Vesicle Coat COPI-coated Vesicle Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding RRNA Binding	Protein Binding Identical Protein Binding Molecular Adaptor Activity Phosphatidic Acid Binding Lipid Transfer Activity
	Biological Process	RRNA Processing Mitochondrial Transcription Protein Targeting To Mitochondrion Heart Development Ribosome Assembly Camera-type Eye Development Mitochondrial Ribosome Assembly Regulation Of Mitochondrial Transcription	Apoptotic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Lipid Storage Response To Nutrient Levels Very-low-density Lipoprotein Particle Assembly Positive Regulation Of Apoptotic Process COPII-coated Vesicle Cargo Loading Regulation Of Triglyceride Metabolic Process Execution Phase Of Apoptosis Intermembrane Lipid Transfer Lipid Droplet Fusion
Pathways		rRNA modification in the mitochondrion
Drugs
Diseases
GWAS			Anorectal malformation ( 31136621) Height ( 28552196) Parent of origin effect on language impairment (paternal) ( 24571439)
Interacting Genes		11 interacting genes: APP ATXN1 BANP CIDEB CRYAA DGAT2L6 EMD FOS OSGIN1 TNFRSF10D UBC	68 interacting genes: ABHD16A AFG1L APOC1 ARL8B ATP5ME ATP5MJ BCL2L2 CAND2 CIDEA CLCN1 CMPK1 COL10A1 COL8A1 COX7C DFFA DFFB DHRSX DNAJA3 FAM218A FAM47E-STBD1 FKBP8 FOXD4L3 FUNDC2 GCSH GNB3 GPAM H4C7 HAPLN2 HCCS HIGD1C IRX2-DT MEST MICOS10 MPC2 MRPL36 MRPL57 MTERF4 NAALAD2 NDRG4 NFU1 NME4 PBX3 PDHX PGLYRP3 PISD PPIF RAMP2 RHBDD2 ROMO1 RTP5 SAA2 SAA4 SAR1B SCO1 SCO2 SDHAF1 SFXN1 SMARCC1 SPG21 TAOK2 TBX2 TEX44 THBD TIMM17B TMEM14B TPRG1 TSR1 UFSP1
Entrez ID		130916	27141
HPRD ID		14699	11981
Ensembl ID		ENSG00000122085	ENSG00000136305
Uniprot IDs		B4DFP7 Q7Z6M4	Q9UHD4
PDB IDs		4FP9 4FZV 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF3 7OF5 7OF7 7OIC 7PD3 8PK0 8QSJ	1D4B
Enriched GO Terms of Interacting Partners?		Response To Light Stimulus Associative Learning Memory Learning Response To Radiation Amyloid Fibril Formation Amyloid-beta Complex Growth Cone Lamellipodium Visual Behavior Regulation Of Response To Calcium Ion Learning Or Memory Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Response To Growth Factor Stimulus Visual Learning Identical Protein Binding TMEM240-body Skeletal Muscle Cell Differentiation Medium-term Memory Cellular Response To Prolactin Acetylcholine Receptor Activator Activity PTB Domain Binding Apoptotic Process Cognition Adult Locomotory Behavior Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Response To Growth Factor Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle System Process Endoplasmic Reticulum Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Nervous System Process Response To Prolactin Conditioned Taste Aversion Acylglycerol Acyl-chain Remodeling Programmed Cell Death Cell Death Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus	Mitochondrion Mitochondrial Inner Membrane Regulation Of Apoptotic DNA Fragmentation Negative Regulation Of Apoptotic DNA Fragmentation High-density Lipoprotein Particle Protein Binding Mitochondrion Organization Mitochondrial Membrane Copper Chaperone Activity Disordered Domain Specific Binding T Cell Apoptotic Process Mitochondrial Matrix Organophosphate Biosynthetic Process Cytochrome Complex Assembly Pyruvate Decarboxylation To Acetyl-CoA Activation-induced Cell Death Of T Cells Mitochondrial Respiratory Chain Complex Assembly Lymphocyte Apoptotic Process Import Into The Mitochondrion Negative Regulation Of Execution Phase Of Apoptosis Protein Localization To Mitochondrion
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