CLK2 and GMCL1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CLK2	GMCL1
Gene Name		CDC-like kinase 2	germ cell-less, spermatogenesis associated 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck	Nuclear Envelope Nuclear Matrix
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding
	Biological Process	Protein Phosphorylation Response To Ionizing Radiation Peptidyl-tyrosine Phosphorylation Response To Retinoic Acid Regulation Of RNA Splicing Negative Regulation Of Gluconeogenesis Protein Autophosphorylation	Regulation Of Transcription, DNA-templated Multicellular Organismal Development Spermatogenesis Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		30 interactors: AKT1 CLK3 CPSF7 ECE1 GMCL1 KLHL2 LNX1 LUZP4 MRPL4 PRPF38A PTPN1 RBM39 RNPS1 RSRP1 SDCBP SNIP1 SNRNP70 SRPK2 SRRM1 TRIM27 U2AF1 UBE2I UBL5 YTHDC1 YWHAG ZNF263 ZNF394 ZNF398 ZNF473 ZRSR2	61 interactors: APLF APOL6 BYSL C21orf2 C5orf60 CCDC25 CHIC2 CIB3 CLK2 CUL3 EMD FAM167A FAM63A FKBP1B FOSL2 FOXR1 FRMD6 GAGE1 GAGE12B GAGE12I GAGE2E GAGE5 GLRX3 GMCL1P1 GRAMD1A HYKK IL17F KAT5 KIFC3 KPNA2 MID1 MID2 MORF4L1 MPPE1 MTRR NEBL NUMA1 PARD6B PARP16 PAX4 PBXIP1 PTPN7 QRICH1 RAD54B SHQ1 SLC15A3 SNX20 STK3 SUMO1 SUMO1P1 SYT17 TCEB3 TMPO TRIM13 TRIM38 TRIM54 TSG101 TSSC4 XAGE2 XAGE3 ZNF250
Entrez ID		1196	64395
HPRD ID		04289	13587
Ensembl ID		ENSG00000176444
Uniprot IDs		A8K7I0 B1AVT0 B7Z8N6 P49760 Q9BRG8	Q53SE7 Q96IK5
PDB IDs		3NR9
Enriched GO Terms of Interacting Partners?		MRNA Processing RNA Processing RNA Splicing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression Termination Of RNA Polymerase II Transcription RNA Metabolic Process DNA-templated Transcription, Termination MRNA 3'-end Processing Cellular Nitrogen Compound Metabolic Process RNA 3'-end Processing Cellular Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Splicing Spliceosomal Complex Assembly Regulation Of MRNA Splicing, Via Spliceosome MRNA Export From Nucleus RNA Export From Nucleus Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Regulation Of RNA Metabolic Process Regulation Of MRNA Processing Transcription, DNA-templated RNA Biosynthetic Process Nucleocytoplasmic Transport Nuclear Transport Cellular Process Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Cellular Macromolecule Biosynthetic Process Nuclear Export MRNA Transport Negative Regulation Of Transferase Activity Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Protein Phosphorylation Protein Ubiquitination Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway RNA Transport Protein Modification By Small Protein Conjugation RNA Localization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Phosphorylation	Protein Localization To Microtubule Double-strand Break Repair Regulation Of Viral Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Viral Transcription Negative Regulation Of Viral Release From Host Cell Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Axon Regeneration Regulation Of Viral Entry Into Host Cell Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Viral Transcription Protein Localization To Cytoskeleton Regulation Of Viral Release From Host Cell DNA Metabolic Process Cellular Protein Modification Process DNA Repair Trophectodermal Cell Differentiation Protein Modification By Small Protein Conjugation Cellular Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of RNA Metabolic Process Proteasomal Protein Catabolic Process Nucleus Organization Regulation Of Gene Expression Positive Regulation Of NF-kappaB Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Cellular Localization Negative Regulation Of Microtubule Depolymerization Cardiac Muscle Thin Filament Assembly Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Ubiquitin-dependent Protein Catabolic Process Blastocyst Formation Response To Ionizing Radiation Modification-dependent Protein Catabolic Process Cellular Response To Interferon-gamma
Tagcloud ?		chek2 comprehensively escc esophageal fance fen1 gc genetics genotyped germline gtf2h3 han hel308 linxian mpg mre11a pole polq propensity rad54b rad54l resampling shanxi smug1 snps sum tdg validate warranted	asm atm bouquet compensate conjugating dmc1 doubling dsbs gadd45a haploid hop2 hr6b insignificant joining ku80 m1jcs mei1 meiosis mlh1 pairing preleptotene prophase segregates spermatocytes spermatogenesis spermiogenesis spo11 terf1 tnp1
Tagcloud (Difference) ?		chek2 comprehensively escc esophageal fance fen1 gc genetics genotyped germline gtf2h3 han hel308 linxian mpg mre11a pole polq propensity rad54b rad54l resampling shanxi smug1 snps sum tdg validate warranted	asm atm bouquet compensate conjugating dmc1 doubling dsbs gadd45a haploid hop2 hr6b insignificant joining ku80 m1jcs mei1 meiosis mlh1 pairing preleptotene prophase segregates spermatocytes spermatogenesis spermiogenesis spo11 terf1 tnp1
Tagcloud (Intersection) ?