GMCL1 and XAGE2

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		GMCL1	XAGE2
Description		germ cell-less 1, spermatogenesis associated	X antigen family member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Matrix
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Germ Cell Development Spermatogenesis Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Atrial fibrillation ( 28416818 29892015 30061737) Colorectal or endometrial cancer ( 26621817) Red cell distribution width ( 32888494) Whole brain grey matter density ( 31530798)
Interacting Genes		98 interacting genes: APLF APOL6 AXIN1 BEGAIN BSCL2 BYSL CCDC13 CCDC25 CDC37 CFAP298 CFAP410 CHIC2 CIB3 CLK2 CUL3 EHHADH ELOA EMD EXOC3 FAM50B FKBP1B FLYWCH1 FOSL2 FOXR1 FRMD6 GAGE1 GAGE10 GAGE12B GAGE12G GAGE12I GAGE12J GAGE2A GAGE2C GAGE2E GAGE5 GLRX3 GOLGA2 GRAMD1A HYKK IL17F KANK2 KAT5 KIFC3 KLHL20 KPNA2 KRT75 LNX1 MID1 MID2 MINDY1 MORF4L1 MPPE1 MTRR MYLIP MYO5B NEBL NFIL3 NTAQ1 NUMA1 PARD6B PARP16 PAX4 PBXIP1 PIBF1 PIH1D2 PPP1R18 PTPN7 QRICH1 RAD54B RANBP3 RASA1 RNF4 RNMT SHQ1 SLC15A3 SNX20 SPATA31J1 STK3 SUMO1 SUMO1P1 SYT17 SYT6 TBC1D1 TLK2 TMPO TRIM13 TRIM21 TRIM38 TRIM54 TSG101 TSSC4 UBE2I XAGE2 YY1 ZBTB24 ZMYM2 ZNF23 ZNF250	7 interacting genes: EHMT2 EPS8 FOXP4 GMCL1 GMCL2 POT1 TERF2IP
Entrez ID		64395	9502
HPRD ID		13587	02332
Ensembl ID		ENSG00000087338	ENSG00000155622
Uniprot IDs		Q53SE7 Q96IK5	Q96GT9
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Positive Regulation Of Viral Life Cycle Ubiquitin Protein Ligase Activity PML Body Protein Modification Process Regulation Of Viral Process Protein Localization To Cytoskeleton Protein Modification By Small Protein Conjugation Suppression Of Viral Release By Host Regulation Of Viral Transcription Negative Regulation Of Viral Transcription Transcription Factor Binding Protein Sumoylation Cytoplasm Post-translational Protein Modification Small Protein Activating Enzyme Binding Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Viral Process Modification-dependent Protein Catabolic Process	Nuclear Telomere Cap Complex Shelterin Complex G-rich Strand Telomeric DNA Binding Telomere Capping Telomere Maintenance Via Telomerase Germ Cell Development RNA-templated DNA Biosynthetic Process Telomeric DNA Binding Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Cellular Component Organization Negative Regulation Of Telomere Maintenance Chromosome Organization Histone H3K56 Methyltransferase Activity Positive Regulation Of Telomere Maintenance Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Negative Regulation Of Chromosome Organization DNA Biosynthetic Process Regulation Of Organelle Organization Regulation Of DNA Metabolic Process Positive Regulation Of Telomeric Loop Disassembly Telomere Maintenance Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Negative Regulation Of DNA Recombination At Telomere Phenotypic Switching 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Telomere Organization Nuclear Matrix Negative Regulation Of DNA Metabolic Process Adult Behavior Regulation Of Double-strand Break Repair Telomeric D-loop Binding Telomere Assembly Negative Regulation Of Nucleobase-containing Compound Metabolic Process Peptidyl-lysine Dimethylation Chromosome Single-stranded Telomeric DNA Binding Chromosome, Telomeric Region Histone H3K27 Methyltransferase Activity Actin Polymerization-dependent Cell Motility Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Protection From Non-homologous End Joining At Telomere Histone H3K9me2 Methyltransferase Activity DEAD/H-box RNA Helicase Binding NMDA Selective Glutamate Receptor Complex Behavioral Response To Ethanol
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?