CLK2 and YTHDC1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CLK2	YTHDC1
Gene Name		CDC-like kinase 2	YTH domain containing 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck	Nucleus Nuclear Body
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding	RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Protein Phosphorylation Response To Ionizing Radiation Peptidyl-tyrosine Phosphorylation Response To Retinoic Acid Regulation Of RNA Splicing Negative Regulation Of Gluconeogenesis Protein Autophosphorylation	MRNA Splice Site Selection
Pathways
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		30 interactors: AKT1 CLK3 CPSF7 ECE1 GMCL1 KLHL2 LNX1 LUZP4 MRPL4 PRPF38A PTPN1 RBM39 RNPS1 RSRP1 SDCBP SNIP1 SNRNP70 SRPK2 SRRM1 TRIM27 U2AF1 UBE2I UBL5 YTHDC1 YWHAG ZNF263 ZNF394 ZNF398 ZNF473 ZRSR2	34 interactors: ABL1 ADAMTS4 CFH CLK2 CORO1A DVL3 EDC4 EMD FYN GOLGA2 HNRNPK KHDRBS1 KHDRBS2 KHDRBS3 KRT18 LAMC3 LAMTOR5 LZTS2 MPRIP PLG PROSER2 RBMY1F SDCBP2 SEPT10 SOX13 SRC SRPK1 SRPK2 SRSF1 SRSF2 TRA2A TRA2B TXK VPS51
Entrez ID		1196	91746
HPRD ID		04289	11689
Ensembl ID		ENSG00000176444	ENSG00000083896
Uniprot IDs		A8K7I0 B1AVT0 B7Z8N6 P49760 Q9BRG8	J3QR07 Q96MU7
PDB IDs		3NR9	2YUD
Enriched GO Terms of Interacting Partners?		MRNA Processing RNA Processing RNA Splicing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression Termination Of RNA Polymerase II Transcription RNA Metabolic Process DNA-templated Transcription, Termination MRNA 3'-end Processing Cellular Nitrogen Compound Metabolic Process RNA 3'-end Processing Cellular Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Splicing Spliceosomal Complex Assembly Regulation Of MRNA Splicing, Via Spliceosome MRNA Export From Nucleus RNA Export From Nucleus Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Regulation Of RNA Metabolic Process Regulation Of MRNA Processing Transcription, DNA-templated RNA Biosynthetic Process Nucleocytoplasmic Transport Nuclear Transport Cellular Process Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Cellular Macromolecule Biosynthetic Process Nuclear Export MRNA Transport Negative Regulation Of Transferase Activity Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Protein Phosphorylation Protein Ubiquitination Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway RNA Transport Protein Modification By Small Protein Conjugation RNA Localization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Phosphorylation	MRNA Metabolic Process MRNA Processing RNA Splicing RNA Processing Peptidyl-tyrosine Autophosphorylation Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Protein Autophosphorylation Regulation Of Cell-cell Adhesion RNA Metabolic Process Peptidyl-tyrosine Phosphorylation Regulation Of Wnt Signaling Pathway Gene Expression Viral Process Innate Immune Response Regulation Of Cell Proliferation Cellular Response To Platelet-derived Growth Factor Stimulus Response To Platelet-derived Growth Factor Regulation Of Cell Adhesion Anatomical Structure Development Leukocyte Migration Regulation Of Canonical Wnt Signaling Pathway Immune Response Regulation Of RNA Metabolic Process Regulation Of Intracellular Transport Cytoplasmic Transport Defense Response Cell Cycle Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Localization Activated T Cell Proliferation Phagocytosis Positive Regulation Of Viral Genome Replication Regulation Of Neuron Death Heterocycle Metabolic Process Immune Response-activating Cell Surface Receptor Signaling Pathway Cellular Aromatic Compound Metabolic Process Nuclear Export Regulation Of T Cell Activation Nucleus Organization Regulation Of Gene Expression Developmental Process Regulation Of Nitrogen Compound Metabolic Process Antigen Receptor-mediated Signaling Pathway Cellular Nitrogen Compound Metabolic Process Cellular Process Golgi To Plasma Membrane Transport
Tagcloud ?		chek2 comprehensively escc esophageal fance fen1 gc genetics genotyped germline gtf2h3 han hel308 linxian mpg mre11a pole polq propensity rad54b rad54l resampling shanxi smug1 snps sum tdg validate warranted
Tagcloud (Difference) ?		chek2 comprehensively escc esophageal fance fen1 gc genetics genotyped germline gtf2h3 han hel308 linxian mpg mre11a pole polq propensity rad54b rad54l resampling shanxi smug1 snps sum tdg validate warranted
Tagcloud (Intersection) ?