CLK2 and ZRSR2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CLK2	ZRSR2
Gene Name		CDC-like kinase 2	zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck	U12-type Spliceosomal Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding	Nucleotide Binding Protein Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding
	Biological Process	Protein Phosphorylation Response To Ionizing Radiation Peptidyl-tyrosine Phosphorylation Response To Retinoic Acid Regulation Of RNA Splicing Negative Regulation Of Gluconeogenesis Protein Autophosphorylation	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		30 interactors: AKT1 CLK3 CPSF7 ECE1 GMCL1 KLHL2 LNX1 LUZP4 MRPL4 PRPF38A PTPN1 RBM39 RNPS1 RSRP1 SDCBP SNIP1 SNRNP70 SRPK2 SRRM1 TRIM27 U2AF1 UBE2I UBL5 YTHDC1 YWHAG ZNF263 ZNF394 ZNF398 ZNF473 ZRSR2	10 interactors: APP CLK2 SDCBP2 SRPK1 SRPK2 SRSF1 SRSF2 SSX2IP U2AF1 U2AF2
Entrez ID		1196	8233
HPRD ID		04289	02068
Ensembl ID		ENSG00000176444	ENSG00000169249
Uniprot IDs		A8K7I0 B1AVT0 B7Z8N6 P49760 Q9BRG8	Q15696
PDB IDs		3NR9
Enriched GO Terms of Interacting Partners?		MRNA Processing RNA Processing RNA Splicing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression Termination Of RNA Polymerase II Transcription RNA Metabolic Process DNA-templated Transcription, Termination MRNA 3'-end Processing Cellular Nitrogen Compound Metabolic Process RNA 3'-end Processing Cellular Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Splicing Spliceosomal Complex Assembly Regulation Of MRNA Splicing, Via Spliceosome MRNA Export From Nucleus RNA Export From Nucleus Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Regulation Of RNA Metabolic Process Regulation Of MRNA Processing Transcription, DNA-templated RNA Biosynthetic Process Nucleocytoplasmic Transport Nuclear Transport Cellular Process Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Cellular Macromolecule Biosynthetic Process Nuclear Export MRNA Transport Negative Regulation Of Transferase Activity Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Protein Phosphorylation Protein Ubiquitination Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway RNA Transport Protein Modification By Small Protein Conjugation RNA Localization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Phosphorylation	MRNA Processing MRNA 3'-end Processing Regulation Of RNA Splicing MRNA Metabolic Process RNA 3'-end Processing RNA Processing Termination Of RNA Polymerase II Transcription RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Processing Nuclear Export MRNA Transport RNA Transport RNA Localization Intracellular Transport Nucleocytoplasmic Transport Establishment Of Localization In Cell Nuclear Transport Cellular Localization Positive Regulation Of Viral Genome Replication RNA Metabolic Process Gene Expression Cytoplasmic Transport Negative Regulation Of Viral Genome Replication Spliceosomal Complex Assembly Transcription From RNA Polymerase II Promoter Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Nuclear Speck Organization Negative Regulation Of Viral Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Synaptic Growth At Neuromuscular Junction Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Transport Nucleus Organization Cellular Nitrogen Compound Metabolic Process Collateral Sprouting In Absence Of Injury Microtubule-based Transport Protein Phosphorylation Cytoskeleton-dependent Intracellular Transport Regulation Of Viral Process Collateral Sprouting
Tagcloud ?		chek2 comprehensively escc esophageal fance fen1 gc genetics genotyped germline gtf2h3 han hel308 linxian mpg mre11a pole polq propensity rad54b rad54l resampling shanxi smug1 snps sum tdg validate warranted	bcl11b cadherin discovered dnm2 druggable exhibitedthe fat1 fbxw7 frequencies guide harboured herc1 jak jak3 lymphoblastic mll2 mutational notch1 notch2 phf6 recurrent regulators reln secretase splicing subclonal unfavourable warranted wt1
Tagcloud (Difference) ?		chek2 comprehensively escc esophageal fance fen1 gc genetics genotyped germline gtf2h3 han hel308 linxian mpg mre11a pole polq propensity rad54b rad54l resampling shanxi smug1 snps sum tdg validate	bcl11b cadherin discovered dnm2 druggable exhibitedthe fat1 fbxw7 frequencies guide harboured herc1 jak jak3 lymphoblastic mll2 mutational notch1 notch2 phf6 recurrent regulators reln secretase splicing subclonal unfavourable wt1
Tagcloud (Intersection) ?		warranted