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CLK2 and CPSF7
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
CLK2
CPSF7
Gene Name
CDC-like kinase 2
cleavage and polyadenylation specific factor 7, 59kDa
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nuclear Speck
Nucleus
Nucleoplasm
MRNA Cleavage Factor Complex
Membrane
Molecular Function
Protein Serine/threonine Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Tyrosine Kinase Activity
Protein Binding
ATP Binding
Nucleotide Binding
Protein Binding
Poly(A) RNA Binding
Biological Process
Protein Phosphorylation
Response To Ionizing Radiation
Peptidyl-tyrosine Phosphorylation
Response To Retinoic Acid
Regulation Of RNA Splicing
Negative Regulation Of Gluconeogenesis
Protein Autophosphorylation
MRNA Splicing, Via Spliceosome
Transcription From RNA Polymerase II Promoter
Termination Of RNA Polymerase II Transcription
RNA Splicing
Gene Expression
MRNA 3'-end Processing
Protein Tetramerization
Pathways
mRNA Splicing
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Transcription
Processing of Capped Intronless Pre-mRNA
mRNA Splicing - Major Pathway
Cleavage of Growing Transcript in the Termination Region
RNA Polymerase II Transcription Termination
Processing of Intronless Pre-mRNAs
mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions
30 interactors:
AKT1
CLK3
CPSF7
ECE1
GMCL1
KLHL2
LNX1
LUZP4
MRPL4
PRPF38A
PTPN1
RBM39
RNPS1
RSRP1
SDCBP
SNIP1
SNRNP70
SRPK2
SRRM1
TRIM27
U2AF1
UBE2I
UBL5
YTHDC1
YWHAG
ZNF263
ZNF394
ZNF398
ZNF473
ZRSR2
22 interactors:
AES
APBB1
ARMC7
ATXN1
CLK2
CSNK2A1
DVL2
EPM2AIP1
EWSR1
GCC1
ITCH
NCK2
NUDT21
PRMT2
RUNX1T1
SEC23B
SMAD3
SNRNP25
SORBS3
U2AF2
WBP4
WWOX
Entrez ID
1196
79869
HPRD ID
04289
16906
Ensembl ID
ENSG00000176444
ENSG00000149532
Uniprot IDs
A8K7I0
B1AVT0
B7Z8N6
P49760
Q9BRG8
B4DGF8
Q8N684
PDB IDs
3NR9
3N9U
Enriched GO Terms of Interacting Partners
?
MRNA Processing
RNA Processing
RNA Splicing
MRNA Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Gene Expression
Termination Of RNA Polymerase II Transcription
RNA Metabolic Process
DNA-templated Transcription, Termination
MRNA 3'-end Processing
Cellular Nitrogen Compound Metabolic Process
RNA 3'-end Processing
Cellular Metabolic Process
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of RNA Splicing
Spliceosomal Complex Assembly
Regulation Of MRNA Splicing, Via Spliceosome
MRNA Export From Nucleus
RNA Export From Nucleus
Negative Regulation Of Protein Kinase Activity
Negative Regulation Of Kinase Activity
Regulation Of RNA Metabolic Process
Regulation Of MRNA Processing
Transcription, DNA-templated
RNA Biosynthetic Process
Nucleocytoplasmic Transport
Nuclear Transport
Cellular Process
Metabolic Process
Regulation Of Metabolic Process
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Cellular Macromolecule Biosynthetic Process
Nuclear Export
MRNA Transport
Negative Regulation Of Transferase Activity
Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Negative Regulation Of Protein Phosphorylation
Protein Ubiquitination
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
RNA Transport
Protein Modification By Small Protein Conjugation
RNA Localization
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Negative Regulation Of Phosphorylation
Regulation Of RNA Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
RNA Metabolic Process
Regulation Of Wnt Signaling Pathway
Positive Regulation Of Metabolic Process
Gene Expression
RNA Processing
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
RNA Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Gene Expression
Regulation Of Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Signal Transduction
Negative Regulation Of Gene Expression
Positive Regulation Of Transcription, DNA-templated
Wnt Signaling Pathway
Regulation Of Signaling
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Regulation Of Growth
Positive Regulation Of Cell Death
Regulation Of Apoptotic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Cell Growth
RNA Splicing
Regulation Of Cell Death
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Signal Transduction
Negative Regulation Of Nucleic Acid-templated Transcription
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Wnt Signaling Pathway
Negative Regulation Of Phosphorylation
Negative Regulation Of Signaling
Cellular Macromolecule Biosynthetic Process
MRNA Processing
Macromolecule Biosynthetic Process
Positive Regulation Of Signal Transduction
Negative Regulation Of Cell Cycle
Termination Of RNA Polymerase II Transcription
Tagcloud
?
chek2
comprehensively
escc
esophageal
fance
fen1
gc
genetics
genotyped
germline
gtf2h3
han
hel308
linxian
mpg
mre11a
pole
polq
propensity
rad54b
rad54l
resampling
shanxi
smug1
snps
sum
tdg
validate
warranted
Tagcloud (Difference)
?
chek2
comprehensively
escc
esophageal
fance
fen1
gc
genetics
genotyped
germline
gtf2h3
han
hel308
linxian
mpg
mre11a
pole
polq
propensity
rad54b
rad54l
resampling
shanxi
smug1
snps
sum
tdg
validate
warranted
Tagcloud (Intersection)
?