CLK2 and ZNF473

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CLK2	ZNF473
Gene Name		CDC-like kinase 2	zinc finger protein 473
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck	Nucleoplasm Cajal Body
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Protein Phosphorylation Response To Ionizing Radiation Peptidyl-tyrosine Phosphorylation Response To Retinoic Acid Regulation Of RNA Splicing Negative Regulation Of Gluconeogenesis Protein Autophosphorylation	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription Histone MRNA 3'-end Processing Histone MRNA Metabolic Process Gene Expression MRNA 3'-end Processing
Pathways			SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs RNA Polymerase II Transcription Generic Transcription Pathway Processing of Capped Intronless Pre-mRNA Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination SLBP independent Processing of Histone Pre-mRNAs
Drugs
Diseases
GWAS
Protein-Protein Interactions		30 interactors: AKT1 CLK3 CPSF7 ECE1 GMCL1 KLHL2 LNX1 LUZP4 MRPL4 PRPF38A PTPN1 RBM39 RNPS1 RSRP1 SDCBP SNIP1 SNRNP70 SRPK2 SRRM1 TRIM27 U2AF1 UBE2I UBL5 YTHDC1 YWHAG ZNF263 ZNF394 ZNF398 ZNF473 ZRSR2	14 interactors: AEN CLK2 DHX57 GPATCH2L KRTAP10-8 KRTAP10-9 LSM11 RNPS1 SLBP TRIM41 ZNF202 ZNF250 ZNF792 ZSCAN12
Entrez ID		1196	25888
HPRD ID		04289	11721
Ensembl ID		ENSG00000176444	ENSG00000142528
Uniprot IDs		A8K7I0 B1AVT0 B7Z8N6 P49760 Q9BRG8	F8WEC7 Q8WTR7
PDB IDs		3NR9	2EMB 2EMC 2EME 2EOU 2EOX 2EOY 2EOZ 2YRH 2YRJ 2YSV 2YTD 2YTE 2YTT 2YU5
Enriched GO Terms of Interacting Partners?		MRNA Processing RNA Processing RNA Splicing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression Termination Of RNA Polymerase II Transcription RNA Metabolic Process DNA-templated Transcription, Termination MRNA 3'-end Processing Cellular Nitrogen Compound Metabolic Process RNA 3'-end Processing Cellular Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Splicing Spliceosomal Complex Assembly Regulation Of MRNA Splicing, Via Spliceosome MRNA Export From Nucleus RNA Export From Nucleus Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Regulation Of RNA Metabolic Process Regulation Of MRNA Processing Transcription, DNA-templated RNA Biosynthetic Process Nucleocytoplasmic Transport Nuclear Transport Cellular Process Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Cellular Macromolecule Biosynthetic Process Nuclear Export MRNA Transport Negative Regulation Of Transferase Activity Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Protein Phosphorylation Protein Ubiquitination Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway RNA Transport Protein Modification By Small Protein Conjugation RNA Localization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Phosphorylation	Termination Of RNA Polymerase II Transcription Histone MRNA 3'-end Processing DNA-templated Transcription, Termination MRNA 3'-end Processing RNA Metabolic Process RNA 3'-end Processing Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Histone MRNA Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process RNA Processing Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process MRNA Export From Nucleus Transcription From RNA Polymerase II Promoter RNA Export From Nucleus MRNA Processing Regulation Of RNA Splicing Nuclear Export MRNA Transport MRNA Metabolic Process RNA Transport Response To Ionizing Radiation Biosynthetic Process RNA Localization Metabolic Process Negative Regulation Of Gluconeogenesis Nucleocytoplasmic Transport Nuclear Transport Regulation Of RNA Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Nuclear DNA Replication Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Gene Expression Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Nitrogen Compound Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Response To Radiation Regulation Of Gluconeogenesis Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Tagcloud ?		chek2 comprehensively escc esophageal fance fen1 gc genetics genotyped germline gtf2h3 han hel308 linxian mpg mre11a pole polq propensity rad54b rad54l resampling shanxi smug1 snps sum tdg validate warranted
Tagcloud (Difference) ?		chek2 comprehensively escc esophageal fance fen1 gc genetics genotyped germline gtf2h3 han hel308 linxian mpg mre11a pole polq propensity rad54b rad54l resampling shanxi smug1 snps sum tdg validate warranted
Tagcloud (Intersection) ?