GMCL1 and PARP16

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		GMCL1	PARP16
Gene Name		germ cell-less, spermatogenesis associated 1	poly (ADP-ribose) polymerase family, member 16
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Nuclear Matrix	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Endoplasmic Reticulum Tubular Network
	Molecular Function		NAD+ ADP-ribosyltransferase Activity Protein Binding Kinase Binding Protein Serine/threonine Kinase Activator Activity
	Biological Process	Regulation Of Transcription, DNA-templated Multicellular Organismal Development Spermatogenesis Cell Differentiation	Protein ADP-ribosylation Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of Cell Death Protein Auto-ADP-ribosylation Positive Regulation Of Protein Serine/threonine Kinase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		61 interactors: APLF APOL6 BYSL C21orf2 C5orf60 CCDC25 CHIC2 CIB3 CLK2 CUL3 EMD FAM167A FAM63A FKBP1B FOSL2 FOXR1 FRMD6 GAGE1 GAGE12B GAGE12I GAGE2E GAGE5 GLRX3 GMCL1P1 GRAMD1A HYKK IL17F KAT5 KIFC3 KPNA2 MID1 MID2 MORF4L1 MPPE1 MTRR NEBL NUMA1 PARD6B PARP16 PAX4 PBXIP1 PTPN7 QRICH1 RAD54B SHQ1 SLC15A3 SNX20 STK3 SUMO1 SUMO1P1 SYT17 TCEB3 TMPO TRIM13 TRIM38 TRIM54 TSG101 TSSC4 XAGE2 XAGE3 ZNF250	2 interactors: GMCL1 NEDD4
Entrez ID		64395	54956
HPRD ID		13587	07919
Ensembl ID			ENSG00000138617
Uniprot IDs		Q53SE7 Q96IK5	Q8N5Y8
PDB IDs			4F0D
Enriched GO Terms of Interacting Partners?		Protein Localization To Microtubule Double-strand Break Repair Regulation Of Viral Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Viral Transcription Negative Regulation Of Viral Release From Host Cell Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Axon Regeneration Regulation Of Viral Entry Into Host Cell Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Viral Transcription Protein Localization To Cytoskeleton Regulation Of Viral Release From Host Cell DNA Metabolic Process Cellular Protein Modification Process DNA Repair Trophectodermal Cell Differentiation Protein Modification By Small Protein Conjugation Cellular Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of RNA Metabolic Process Proteasomal Protein Catabolic Process Nucleus Organization Regulation Of Gene Expression Positive Regulation Of NF-kappaB Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Cellular Localization Negative Regulation Of Microtubule Depolymerization Cardiac Muscle Thin Filament Assembly Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Ubiquitin-dependent Protein Catabolic Process Blastocyst Formation Response To Ionizing Radiation Modification-dependent Protein Catabolic Process Cellular Response To Interferon-gamma	Transmission Of Virus Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Development Involved In Symbiotic Interaction Progesterone Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Glucocorticoid Receptor Signaling Pathway Protein Targeting To Lysosome Negative Regulation Of Sodium Ion Transport Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Protein Localization To Lysosome Receptor Catabolic Process Protein Targeting To Vacuole Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Establishment Of Protein Localization To Vacuole Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Protein K63-linked Ubiquitination Endocardial Cushion Development Regulation Of Potassium Ion Transmembrane Transport Protein Monoubiquitination Receptor Internalization Lysosomal Transport Neuromuscular Junction Development Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Response To UV Regulation Of Potassium Ion Transport Outflow Tract Morphogenesis Regulation Of Sodium Ion Transport Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Dendrite Morphogenesis Intracellular Steroid Hormone Receptor Signaling Pathway Vacuolar Transport Receptor Metabolic Process Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Synapse Organization Regulation Of Synapse Structure Or Activity Cellular Response To Light Stimulus Negative Regulation Of Ion Transport Interaction With Host Regulation Of Dendrite Development Negative Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Nucleocytoplasmic Transport Response To Calcium Ion
Tagcloud ?		asm atm bouquet compensate conjugating dmc1 doubling dsbs gadd45a haploid hop2 hr6b insignificant joining ku80 m1jcs mei1 meiosis mlh1 pairing preleptotene prophase segregates spermatocytes spermatogenesis spermiogenesis spo11 terf1 tnp1	adp artd1 artd15 cisternae endoplasmic folding interconnected karyopherin localisation membranous moiety mono nad nicotinamide nucleocytoplasmic organelles poly reticulum ribose ribosylation ribosyltransferase ribosyltransferases shed shuttling specialised subcellular trafficking tubules
Tagcloud (Difference) ?		asm atm bouquet compensate conjugating dmc1 doubling dsbs gadd45a haploid hop2 hr6b insignificant joining ku80 m1jcs mei1 meiosis mlh1 pairing preleptotene prophase segregates spermatocytes spermatogenesis spermiogenesis spo11 terf1 tnp1	adp artd1 artd15 cisternae endoplasmic folding interconnected karyopherin localisation membranous moiety mono nad nicotinamide nucleocytoplasmic organelles poly reticulum ribose ribosylation ribosyltransferase ribosyltransferases shed shuttling specialised subcellular trafficking tubules
Tagcloud (Intersection) ?