GMCL1 and FOXR1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		GMCL1	FOXR1
Description		germ cell-less 1, spermatogenesis associated	forkhead box R1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Matrix	Chromatin Nucleus Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Germ Cell Development Spermatogenesis Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Brain Development Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Atrial fibrillation ( 28416818 29892015 30061737) Colorectal or endometrial cancer ( 26621817) Red cell distribution width ( 32888494) Whole brain grey matter density ( 31530798)	Asthma ( 31959851)
Interacting Genes		98 interacting genes: APLF APOL6 AXIN1 BEGAIN BSCL2 BYSL CCDC13 CCDC25 CDC37 CFAP298 CFAP410 CHIC2 CIB3 CLK2 CUL3 EHHADH ELOA EMD EXOC3 FAM50B FKBP1B FLYWCH1 FOSL2 FOXR1 FRMD6 GAGE1 GAGE10 GAGE12B GAGE12G GAGE12I GAGE12J GAGE2A GAGE2C GAGE2E GAGE5 GLRX3 GOLGA2 GRAMD1A HYKK IL17F KANK2 KAT5 KIFC3 KLHL20 KPNA2 KRT75 LNX1 MID1 MID2 MINDY1 MORF4L1 MPPE1 MTRR MYLIP MYO5B NEBL NFIL3 NTAQ1 NUMA1 PARD6B PARP16 PAX4 PBXIP1 PIBF1 PIH1D2 PPP1R18 PTPN7 QRICH1 RAD54B RANBP3 RASA1 RNF4 RNMT SHQ1 SLC15A3 SNX20 SPATA31J1 STK3 SUMO1 SUMO1P1 SYT17 SYT6 TBC1D1 TLK2 TMPO TRIM13 TRIM21 TRIM38 TRIM54 TSG101 TSSC4 UBE2I XAGE2 YY1 ZBTB24 ZMYM2 ZNF23 ZNF250	6 interacting genes: BANP CEP19 DPPA4 GMCL1 MEOX2 PPCDC
Entrez ID		64395	283150
HPRD ID		13587	13551
Ensembl ID		ENSG00000087338	ENSG00000176302
Uniprot IDs		Q53SE7 Q96IK5	B0YJ16 Q6PIV2
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Positive Regulation Of Viral Life Cycle Ubiquitin Protein Ligase Activity PML Body Protein Modification Process Regulation Of Viral Process Protein Localization To Cytoskeleton Protein Modification By Small Protein Conjugation Suppression Of Viral Release By Host Regulation Of Viral Transcription Negative Regulation Of Viral Transcription Transcription Factor Binding Protein Sumoylation Cytoplasm Post-translational Protein Modification Small Protein Activating Enzyme Binding Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Viral Process Modification-dependent Protein Catabolic Process	Phosphopantothenoylcysteine Decarboxylase Activity Phosphopantothenoylcysteine Decarboxylase Complex Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment
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