GMCL1 and PTPN7

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		GMCL1	PTPN7
Gene Name		germ cell-less, spermatogenesis associated 1	protein tyrosine phosphatase, non-receptor type 7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Nuclear Matrix	Cytoplasm Cytosol Cytoskeleton Cytoplasmic Side Of Plasma Membrane
	Molecular Function		Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Multicellular Organismal Development Spermatogenesis Cell Differentiation	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation
Pathways
Drugs
Diseases
GWAS			Breast cancer ( 23535733)
Protein-Protein Interactions		61 interactors: APLF APOL6 BYSL C21orf2 C5orf60 CCDC25 CHIC2 CIB3 CLK2 CUL3 EMD FAM167A FAM63A FKBP1B FOSL2 FOXR1 FRMD6 GAGE1 GAGE12B GAGE12I GAGE2E GAGE5 GLRX3 GMCL1P1 GRAMD1A HYKK IL17F KAT5 KIFC3 KPNA2 MID1 MID2 MORF4L1 MPPE1 MTRR NEBL NUMA1 PARD6B PARP16 PAX4 PBXIP1 PTPN7 QRICH1 RAD54B SHQ1 SLC15A3 SNX20 STK3 SUMO1 SUMO1P1 SYT17 TCEB3 TMPO TRIM13 TRIM38 TRIM54 TSG101 TSSC4 XAGE2 XAGE3 ZNF250	7 interactors: APP CCDC57 GMCL1 MAPK1 MAPK14 MAPK3 PRKACA
Entrez ID		64395	5778
HPRD ID		13587	01480
Ensembl ID			ENSG00000143851
Uniprot IDs		Q53SE7 Q96IK5	B4DZD9 P35236
PDB IDs			1ZC0 2A3K 2GP0 2GPH 2HVL 2QDC 2QDM 2QDP 3D42 3D44 3O4S 3O4T 3O4U
Enriched GO Terms of Interacting Partners?		Protein Localization To Microtubule Double-strand Break Repair Regulation Of Viral Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Viral Transcription Negative Regulation Of Viral Release From Host Cell Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Axon Regeneration Regulation Of Viral Entry Into Host Cell Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Viral Transcription Protein Localization To Cytoskeleton Regulation Of Viral Release From Host Cell DNA Metabolic Process Cellular Protein Modification Process DNA Repair Trophectodermal Cell Differentiation Protein Modification By Small Protein Conjugation Cellular Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of RNA Metabolic Process Proteasomal Protein Catabolic Process Nucleus Organization Regulation Of Gene Expression Positive Regulation Of NF-kappaB Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Cellular Localization Negative Regulation Of Microtubule Depolymerization Cardiac Muscle Thin Filament Assembly Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Ubiquitin-dependent Protein Catabolic Process Blastocyst Formation Response To Ionizing Radiation Modification-dependent Protein Catabolic Process Cellular Response To Interferon-gamma	Platelet Activation Vascular Endothelial Growth Factor Receptor Signaling Pathway Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Lipopolysaccharide-mediated Signaling Pathway Wound Healing Chemotaxis Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Cell Activation Response To Wounding Regulation Of Protein Kinase Activity Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Regulation Of Kinase Activity Activation Of Protein Kinase Activity Regulation Of Golgi Inheritance Innate Immune Response Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Regulation Of MAP Kinase Activity TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Caveolin-mediated Endocytosis MyD88-dependent Toll-like Receptor Signaling Pathway Apoptotic Process Toll-like Receptor 4 Signaling Pathway Programmed Cell Death Cell Death Death Regulation Of Protein Phosphorylation Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Golgi Organization Response To Abiotic Stimulus Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Intracellular Transport Positive Regulation Of MAPK Cascade Toll-like Receptor Signaling Pathway Positive Regulation Of Protein Kinase Activity Positive Regulation Of Protein Metabolic Process Peptidyl-serine Phosphorylation Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Locomotion Response To Peptide Positive Regulation Of Kinase Activity
Tagcloud ?		asm atm bouquet compensate conjugating dmc1 doubling dsbs gadd45a haploid hop2 hr6b insignificant joining ku80 m1jcs mei1 meiosis mlh1 pairing preleptotene prophase segregates spermatocytes spermatogenesis spermiogenesis spo11 terf1 tnp1
Tagcloud (Difference) ?		asm atm bouquet compensate conjugating dmc1 doubling dsbs gadd45a haploid hop2 hr6b insignificant joining ku80 m1jcs mei1 meiosis mlh1 pairing preleptotene prophase segregates spermatocytes spermatogenesis spermiogenesis spo11 terf1 tnp1
Tagcloud (Intersection) ?