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CLK2 and SRRM1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
CLK2
SRRM1
Gene Name
CDC-like kinase 2
serine/arginine repetitive matrix 1
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nuclear Speck
Nucleus
Nucleoplasm
Cytosol
Nuclear Matrix
Nuclear Speck
Catalytic Step 2 Spliceosome
Molecular Function
Protein Serine/threonine Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Tyrosine Kinase Activity
Protein Binding
ATP Binding
DNA Binding
Poly(A) RNA Binding
Biological Process
Protein Phosphorylation
Response To Ionizing Radiation
Peptidyl-tyrosine Phosphorylation
Response To Retinoic Acid
Regulation Of RNA Splicing
Negative Regulation Of Gluconeogenesis
Protein Autophosphorylation
RNA Splicing, Via Transesterification Reactions
MRNA Splicing, Via Spliceosome
Transcription From RNA Polymerase II Promoter
Termination Of RNA Polymerase II Transcription
MRNA Export From Nucleus
RNA Splicing
Gene Expression
MRNA 3'-end Processing
Pathways
mRNA Splicing
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Transcription
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
Transport of Mature Transcript to Cytoplasm
Cleavage of Growing Transcript in the Termination Region
RNA Polymerase II Transcription Termination
mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions
30 interactors:
AKT1
CLK3
CPSF7
ECE1
GMCL1
KLHL2
LNX1
LUZP4
MRPL4
PRPF38A
PTPN1
RBM39
RNPS1
RSRP1
SDCBP
SNIP1
SNRNP70
SRPK2
SRRM1
TRIM27
U2AF1
UBE2I
UBL5
YTHDC1
YWHAG
ZNF263
ZNF394
ZNF398
ZNF473
ZRSR2
11 interactors:
ABI1
CLK2
CSNK2A1
DEK
FUS
PIN1
SPOP
SRPK1
SRPK2
SRRM2
YWHAG
Entrez ID
1196
10250
HPRD ID
04289
10441
Ensembl ID
ENSG00000176444
ENSG00000133226
Uniprot IDs
A8K7I0
B1AVT0
B7Z8N6
P49760
Q9BRG8
E9PCT1
Q8IYB3
PDB IDs
3NR9
1MP1
Enriched GO Terms of Interacting Partners
?
MRNA Processing
RNA Processing
RNA Splicing
MRNA Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Gene Expression
Termination Of RNA Polymerase II Transcription
RNA Metabolic Process
DNA-templated Transcription, Termination
MRNA 3'-end Processing
Cellular Nitrogen Compound Metabolic Process
RNA 3'-end Processing
Cellular Metabolic Process
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of RNA Splicing
Spliceosomal Complex Assembly
Regulation Of MRNA Splicing, Via Spliceosome
MRNA Export From Nucleus
RNA Export From Nucleus
Negative Regulation Of Protein Kinase Activity
Negative Regulation Of Kinase Activity
Regulation Of RNA Metabolic Process
Regulation Of MRNA Processing
Transcription, DNA-templated
RNA Biosynthetic Process
Nucleocytoplasmic Transport
Nuclear Transport
Cellular Process
Metabolic Process
Regulation Of Metabolic Process
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Cellular Macromolecule Biosynthetic Process
Nuclear Export
MRNA Transport
Negative Regulation Of Transferase Activity
Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Negative Regulation Of Protein Phosphorylation
Protein Ubiquitination
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
RNA Transport
Protein Modification By Small Protein Conjugation
RNA Localization
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Negative Regulation Of Phosphorylation
Regulation Of RNA Splicing
RNA Splicing
MRNA Processing
Positive Regulation Of Viral Genome Replication
MRNA Metabolic Process
RNA Processing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Cellular Protein Modification Process
Protein Phosphorylation
Negative Regulation Of Viral Genome Replication
Innate Immune Response
Regulation Of MRNA Splicing, Via Spliceosome
Regulation Of Viral Genome Replication
Nuclear Speck Organization
Positive Regulation Of Viral Process
Negative Regulation Of Viral Process
Regulation Of MRNA Processing
Phosphorylation
Cellular Protein Metabolic Process
Cellular Metabolic Process
Positive Regulation Of Type B Pancreatic Cell Apoptotic Process
Nucleus Organization
Regulation Of Mitotic Nuclear Division
RNA Metabolic Process
Immune Response
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Gene Expression
Lamellipodium Morphogenesis
Regulation Of Viral Process
Defense Response
Positive Regulation Of Cell Death
Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Regulation Of Apoptotic Process
Signal Transduction
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Cell Death
Sperm Chromatin Condensation
Protein Metabolic Process
Signaling
Regulation Of Metabolic Process
Regulation Of Cell Division
Negative Regulation Of Gluconeogenesis
Cell Communication
Phosphate-containing Compound Metabolic Process
Peptidyl-tyrosine Phosphorylation
Regulation Of Organelle Organization
Megakaryocyte Development
Tagcloud
?
chek2
comprehensively
escc
esophageal
fance
fen1
gc
genetics
genotyped
germline
gtf2h3
han
hel308
linxian
mpg
mre11a
pole
polq
propensity
rad54b
rad54l
resampling
shanxi
smug1
snps
sum
tdg
validate
warranted
Tagcloud (Difference)
?
chek2
comprehensively
escc
esophageal
fance
fen1
gc
genetics
genotyped
germline
gtf2h3
han
hel308
linxian
mpg
mre11a
pole
polq
propensity
rad54b
rad54l
resampling
shanxi
smug1
snps
sum
tdg
validate
warranted
Tagcloud (Intersection)
?