GMCL1 and FKBP1B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		GMCL1	FKBP1B
Description		germ cell-less 1, spermatogenesis associated	FKBP prolyl isomerase 1B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Matrix	Cytoplasm Membrane Sarcoplasmic Reticulum Z Disc Sarcoplasmic Reticulum Membrane Calcium Channel Complex
	Molecular Function	Protein Binding Identical Protein Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Signaling Receptor Binding Calcium Channel Regulator Activity Protein Binding FK506 Binding Isomerase Activity Calcium Channel Inhibitor Activity Transmembrane Transporter Binding
	Biological Process	Germ Cell Development Spermatogenesis Cell Differentiation	Regulation Of Heart Rate Protein Folding 'de Novo' Protein Folding Smooth Muscle Contraction Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Glucose Negative Regulation Of Heart Rate Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Neuronal Action Potential Propagation Calcium-mediated Signaling Insulin Secretion Insulin Secretion Involved In Cellular Response To Glucose Stimulus Protein Refolding T Cell Proliferation Negative Regulation Of Calcium-mediated Signaling Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Sequestering Of Calcium Ion Protein Maturation Response To Redox State Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Pathways			Stimuli-sensing channels Ion homeostasis
Drugs
Diseases
GWAS		Atrial fibrillation ( 28416818 29892015 30061737) Colorectal or endometrial cancer ( 26621817) Red cell distribution width ( 32888494) Whole brain grey matter density ( 31530798)	Chronotype ( 27494321) Quantitative traits ( 19197348)
Interacting Genes		98 interacting genes: APLF APOL6 AXIN1 BEGAIN BSCL2 BYSL CCDC13 CCDC25 CDC37 CFAP298 CFAP410 CHIC2 CIB3 CLK2 CUL3 EHHADH ELOA EMD EXOC3 FAM50B FKBP1B FLYWCH1 FOSL2 FOXR1 FRMD6 GAGE1 GAGE10 GAGE12B GAGE12G GAGE12I GAGE12J GAGE2A GAGE2C GAGE2E GAGE5 GLRX3 GOLGA2 GRAMD1A HYKK IL17F KANK2 KAT5 KIFC3 KLHL20 KPNA2 KRT75 LNX1 MID1 MID2 MINDY1 MORF4L1 MPPE1 MTRR MYLIP MYO5B NEBL NFIL3 NTAQ1 NUMA1 PARD6B PARP16 PAX4 PBXIP1 PIBF1 PIH1D2 PPP1R18 PTPN7 QRICH1 RAD54B RANBP3 RASA1 RNF4 RNMT SHQ1 SLC15A3 SNX20 SPATA31J1 STK3 SUMO1 SUMO1P1 SYT17 SYT6 TBC1D1 TLK2 TMPO TRIM13 TRIM21 TRIM38 TRIM54 TSG101 TSSC4 UBE2I XAGE2 YY1 ZBTB24 ZMYM2 ZNF23 ZNF250	12 interacting genes: ADAMTSL4 BMPR1A CAMK2D GMCL1 KRT31 KRT40 KRTAP1-1 REL RYR2 RYR3 TGFBR1 TRIM69
Entrez ID		64395	2281
HPRD ID		13587	02795
Ensembl ID		ENSG00000087338	ENSG00000119782
Uniprot IDs		Q53SE7 Q96IK5	F8W6G9 P68106
PDB IDs			1C9H 4C02 4IQ2 4IQC 5HKG 5L1D 5T15 5T9M 5T9N 5T9R 5T9S 5T9V 5TA3 5TAL 5TAM 5TAN 5TAP 5TAQ 5TAS 5TAT 5TAU 5TAV 5TAW 5TAX 5TAY 5TAZ 5TB0 5TB1 5TB2 5TB3 5TB4 6JGZ 6JH6 6JHN 6JI0 6JI8 6JII 6JIU 6JIY 6JRR 6JRS 6M2W 6PV6 6W1N 6WOT 6WOU 6WOV 6X32 6X33 6X34 6X35 6X36 7CF9 7JMF 7JMG 7JMH 7JMI 7JMJ 7M6A 7M6L 7T64 7T65 7U9Q 7U9R 7U9T 7U9X 7U9Z 7UA1 7UA3 7UA4 7UA5 7UA9 7VML 7VMM 7VMN 7VMO 7VMP 7VMQ 7VMR 7VMS 8DTY 8DTZ 8DUJ 8DVE 8DVV 8SEN 8SEO 8SEP 8SEQ 8SER 8SES 8SET 8UQ2 8UQ3 8UQ4 8UXC 8UXE 8UXF 8UXG 8UXH 8UXI 8UXL 8UXM 8XJI 8XKH 8XLF 8XLH 8Y40 9C1E 9C1F 9CGP 9CGQ
Enriched GO Terms of Interacting Partners?		Protein Binding Positive Regulation Of Viral Life Cycle Ubiquitin Protein Ligase Activity PML Body Protein Modification Process Regulation Of Viral Process Protein Localization To Cytoskeleton Protein Modification By Small Protein Conjugation Suppression Of Viral Release By Host Regulation Of Viral Transcription Negative Regulation Of Viral Transcription Transcription Factor Binding Protein Sumoylation Cytoplasm Post-translational Protein Modification Small Protein Activating Enzyme Binding Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Viral Process Modification-dependent Protein Catabolic Process	Ventricular Cardiac Muscle Tissue Morphogenesis Tissue Morphogenesis Transforming Growth Factor Beta Receptor Activity, Type I Sarcoplasmic Reticulum Membrane Calcium-induced Calcium Release Activity Ryanodine-sensitive Calcium-release Channel Activity Cardiac Muscle Tissue Morphogenesis Muscle Tissue Morphogenesis Ventricular Compact Myocardium Morphogenesis Sarcoplasmic Reticulum Intracellularly Gated Calcium Channel Activity Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Cellular Response To Caffeine Release Of Sequestered Calcium Ion Into Cytosol By Endoplasmic Reticulum Transmembrane Receptor Protein Serine/threonine Kinase Activity Cellular Response To Purine-containing Compound Keratin Filament Ventricular Trabecula Myocardium Morphogenesis Sarcoplasmic Reticulum Calcium Ion Transport Response To Caffeine Sarcolemma Smooth Endoplasmic Reticulum Heart Trabecula Morphogenesis Regulation Of Sequestering Of Calcium Ion Response To Calcium Ion Intracellular Monoatomic Cation Homeostasis Inorganic Ion Homeostasis Intracellular Monoatomic Ion Homeostasis Regulation Of The Force Of Heart Contraction Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Calcium Channel Complex Intermediate Filament Regulation Of Cardiac Muscle Cell Action Potential Calcium-mediated Signaling Monoatomic Cation Homeostasis Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Monoatomic Ion Homeostasis Intracellular Calcium Ion Homeostasis Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Calmodulin Binding Cellular Response To Alkaloid Ventricular Septum Morphogenesis Regulation Of Cardiac Muscle Cell Proliferation Intracellular Chemical Homeostasis Positive Regulation Of SMAD Protein Signal Transduction Calcium Ion Homeostasis SMAD Binding Regulation Of Cardiac Muscle Cell Apoptotic Process Regulation Of Neural Crest Cell Differentiation Neural Plate Mediolateral Regionalization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?