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DDX42 and SF3B4
Number of citations of the paper that reports this interaction (PMID
22365833
)
24
Data Source:
BioGRID
(two hybrid)
DDX42
SF3B4
Gene Name
DEAD (Asp-Glu-Ala-Asp) box helicase 42
splicing factor 3b, subunit 4, 49kDa
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cajal Body
Membrane
Nuclear Speck
Nucleoplasm
Spliceosomal Complex
U12-type Spliceosomal Complex
Molecular Function
Helicase Activity
Protein Binding
ATP Binding
Poly(A) RNA Binding
Nucleotide Binding
Protein Binding
Poly(A) RNA Binding
Biological Process
Protein Localization
Metabolic Process
RNA Splicing, Via Transesterification Reactions
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Gene Expression
Positive Regulation Of MRNA Splicing, Via Spliceosome
Pathways
Processing of Capped Intron-Containing Pre-mRNA
mRNA Splicing
mRNA Splicing - Minor Pathway
mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Height (
20881960
18391951
)
Protein-Protein Interactions
10 interactors:
APP
DHX15
FBXO25
PRPF19
RECQL5
SF3A1
SF3B4
SNRPC
U2SURP
UBC
42 interactors:
APBB1
BAG3
BAIAP2
BMPR1A
CHERP
CWF19L2
DDX17
DDX42
EFTUD2
EWSR1
FKBP1A
FRK
GRB2
HNRNPD
HNRNPF
HNRNPH1
HNRNPUL1
HSPB7
ILF3
ITSN1
MAPK9
METTL17
NCK2
NUB1
PPP1R16B
PRPF40A
RBM39
RBM4
SEC24D
SF1
SF3B2
SRSF6
SS18L1
STK19
SUMO4
TCAF1
TCERG1
UBASH3A
UBC
WBP4
WDR77
ZCCHC10
Entrez ID
11325
10262
HPRD ID
09909
12028
Ensembl ID
ENSG00000198231
ENSG00000143368
Uniprot IDs
Q86XP3
B3KUJ0
Q15427
PDB IDs
1X5T
1X5U
Enriched GO Terms of Interacting Partners
?
RNA Processing
MRNA Processing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
MRNA Metabolic Process
RNA Splicing
Spliceosomal Complex Assembly
Nucleobase-containing Compound Metabolic Process
RNA Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Gene Expression
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Ribonucleoprotein Complex Assembly
Positive Regulation Of MRNA Splicing, Via Spliceosome
Positive Regulation Of RNA Splicing
Regulation Of Cell Cycle Phase Transition
Spliceosomal SnRNP Assembly
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
MRNA Splice Site Selection
Cellular Metabolic Process
Ribonucleoprotein Complex Biogenesis
Signal Transduction Involved In DNA Damage Checkpoint
Signal Transduction Involved In Cell Cycle Checkpoint
Regulation Of MRNA Splicing, Via Spliceosome
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Generation Of Catalytic Spliceosome For First Transesterification Step
Regulation Of ERBB Signaling Pathway
Regulation Of MRNA Processing
Signal Transduction In Response To DNA Damage
Regulation Of RNA Splicing
Synaptic Growth At Neuromuscular Junction
Regulation Of Cell Cycle Process
Collateral Sprouting In Absence Of Injury
Protein Ubiquitination
Notch Signaling Pathway
MRNA 5'-splice Site Recognition
DNA Repair
Protein Modification By Small Protein Conjugation
DNA Damage Checkpoint
Cellular Macromolecular Complex Assembly
Collateral Sprouting
Axon Midline Choice Point Recognition
MRNA 3'-splice Site Recognition
Protein Polyubiquitination
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Positive Regulation Of Gene Expression
Axon Choice Point Recognition
Negative Regulation Of Neuron Differentiation
RNA Processing
RNA Splicing
MRNA Processing
MRNA Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Gene Expression
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Nitrogen Compound Metabolic Process
Regulation Of RNA Splicing
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
Circadian Regulation Of Translation
Regulation Of Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Transcription, DNA-templated
RNA Biosynthetic Process
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Macromolecule Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Metabolic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Neuron Projection Development
Cellular Response To Growth Factor Stimulus
Regulation Of ERBB Signaling Pathway
Response To Growth Factor
Negative Regulation Of Protein Metabolic Process
Immune System Process
Response To External Stimulus
Regulation Of Circadian Rhythm
Regulation Of Protein Metabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Neuron Development
Posttranscriptional Regulation Of Gene Expression
Positive Regulation Of Signal Transduction
Regulation Of Cellular Process
Stress-activated MAPK Cascade
Fc Receptor Signaling Pathway
Regulation Of Cellular Protein Metabolic Process
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