SF3B4 and HNRNPF

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		SF3B4	HNRNPF
Gene Name		splicing factor 3b, subunit 4, 49kDa	heterogeneous nuclear ribonucleoprotein F
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex	Nucleus Nucleoplasm Membrane Catalytic Step 2 Spliceosome
	Molecular Function	Nucleotide Binding Protein Binding Poly(A) RNA Binding	Nucleotide Binding RNA Binding Single-stranded RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression Positive Regulation Of MRNA Splicing, Via Spliceosome	MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing Gene Expression Regulation Of RNA Splicing
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Height ( 20881960 18391951)
Protein-Protein Interactions		42 interactors: APBB1 BAG3 BAIAP2 BMPR1A CHERP CWF19L2 DDX17 DDX42 EFTUD2 EWSR1 FKBP1A FRK GRB2 HNRNPD HNRNPF HNRNPH1 HNRNPUL1 HSPB7 ILF3 ITSN1 MAPK9 METTL17 NCK2 NUB1 PPP1R16B PRPF40A RBM39 RBM4 SEC24D SF1 SF3B2 SRSF6 SS18L1 STK19 SUMO4 TCAF1 TCERG1 UBASH3A UBC WBP4 WDR77 ZCCHC10	33 interactors: AES C1orf94 CCDC33 DZIP3 EIF4ENIF1 ERG HNRNPA0 HNRNPD HNRNPH1 HNRNPH3 HNRNPM HNRNPUL1 HSFY1 IKZF3 NCBP1 NCBP2 NDRG1 POLR2A PRPF40A RBFOX1 RBFOX2 RBM4 SF1 SF3B4 SNRPC SUMO4 TFG TGM2 TOE1 TXNL4A VAV2 YWHAQ ZNF689
Entrez ID		10262	3185
HPRD ID		12028	03023
Ensembl ID		ENSG00000143368	ENSG00000169813
Uniprot IDs		B3KUJ0 Q15427	P52597
PDB IDs		1X5T 1X5U	2HGL 2HGM 2HGN 2KFY 2KG0 2KG1 3TFY
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Regulation Of RNA Metabolic Process Regulation Of Gene Expression Circadian Regulation Of Translation Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated RNA Biosynthetic Process Enzyme Linked Receptor Protein Signaling Pathway Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuron Projection Development Cellular Response To Growth Factor Stimulus Regulation Of ERBB Signaling Pathway Response To Growth Factor Negative Regulation Of Protein Metabolic Process Immune System Process Response To External Stimulus Regulation Of Circadian Rhythm Regulation Of Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neuron Development Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Signal Transduction Regulation Of Cellular Process Stress-activated MAPK Cascade Fc Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process	RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Nitrogen Compound Metabolic Process MRNA Cis Splicing, Via Spliceosome Regulation Of Gene Expression Ribonucleoprotein Complex Assembly Regulation Of RNA Metabolic Process Regulation Of MRNA Processing Cellular Metabolic Process 7-methylguanosine MRNA Capping 7-methylguanosine RNA Capping Regulation Of Nitrogen Compound Metabolic Process Spliceosomal SnRNP Assembly Circadian Regulation Of Translation Positive Regulation Of Viral Transcription Ribonucleoprotein Complex Biogenesis Transcription, DNA-templated Spliceosomal Complex Assembly Transcription Elongation From RNA Polymerase II Promoter Gene Silencing By RNA Regulation Of MRNA Splicing, Via Spliceosome RNA Biosynthetic Process Regulation Of Viral Transcription Regulation Of Translational Initiation Positive Regulation Of Viral Process DNA-templated Transcription, Elongation Posttranscriptional Regulation Of Gene Expression Regulation Of Metabolic Process Gene Silencing Histone MRNA Metabolic Process Regulation Of Translation Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Transport Cellular Macromolecule Biosynthetic Process RNA Localization Macromolecule Biosynthetic Process Positive Regulation Of RNA Splicing Regulation Of Viral Process Cellular Macromolecular Complex Assembly
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