SF3B4 and ILF3

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		SF3B4	ILF3
Gene Name		splicing factor 3b, subunit 4, 49kDa	interleukin enhancer binding factor 3, 90kDa
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Membrane Ribonucleoprotein Complex
	Molecular Function	Nucleotide Binding Protein Binding Poly(A) RNA Binding	DNA Binding RNA Binding Double-stranded RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression Positive Regulation Of MRNA Splicing, Via Spliceosome	Transcription, DNA-templated Protein Phosphorylation Negative Regulation Of Translation Negative Regulation Of Viral Genome Replication Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Defense Response To Virus
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Height ( 20881960 18391951)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		42 interactors: APBB1 BAG3 BAIAP2 BMPR1A CHERP CWF19L2 DDX17 DDX42 EFTUD2 EWSR1 FKBP1A FRK GRB2 HNRNPD HNRNPF HNRNPH1 HNRNPUL1 HSPB7 ILF3 ITSN1 MAPK9 METTL17 NCK2 NUB1 PPP1R16B PRPF40A RBM39 RBM4 SEC24D SF1 SF3B2 SRSF6 SS18L1 STK19 SUMO4 TCAF1 TCERG1 UBASH3A UBC WBP4 WDR77 ZCCHC10	26 interactors: DHX9 EIF2AK2 ERG FUS GDF9 HNRNPH2 IL7R KRTAP4-12 LNX1 MAGEA11 MDFI NDRG1 PLSCR1 PRMT1 RBM5 RBPMS RNF113A SF1 SF3B4 SMN1 SNRPC TRIP6 XAB2 XPO5 ZNF346 ZNF830
Entrez ID		10262	3609
HPRD ID		12028	04420
Ensembl ID		ENSG00000143368	ENSG00000129351
Uniprot IDs		B3KUJ0 Q15427	Q12906
PDB IDs		1X5T 1X5U	2L33 3P1X
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Regulation Of RNA Metabolic Process Regulation Of Gene Expression Circadian Regulation Of Translation Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated RNA Biosynthetic Process Enzyme Linked Receptor Protein Signaling Pathway Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuron Projection Development Cellular Response To Growth Factor Stimulus Regulation Of ERBB Signaling Pathway Response To Growth Factor Negative Regulation Of Protein Metabolic Process Immune System Process Response To External Stimulus Regulation Of Circadian Rhythm Regulation Of Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neuron Development Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Signal Transduction Regulation Of Cellular Process Stress-activated MAPK Cascade Fc Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process Gene Expression RNA Metabolic Process Spliceosomal Complex Assembly Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Regulation Of Gene Expression Regulation Of Female Gonad Development Ribonucleoprotein Complex Biogenesis Regulation Of Hematopoietic Progenitor Cell Differentiation Cellular Metabolic Process Regulation Of Protein Import Into Nucleus Spliceosomal SnRNP Assembly Regulation Of Nitrogen Compound Metabolic Process MRNA Splice Site Selection Negative Regulation Of Viral Genome Replication Regulation Of Protein Localization To Nucleus Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Evasion Or Tolerance By Virus Of Host Immune Response Negative Regulation Of Potassium Ion Export Regulation Of Nucleocytoplasmic Transport In Utero Embryonic Development Regulation Of RNA Metabolic Process Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Intracellular Protein Transport Regulation Of Heart Rate By Hormone Interleukin-7-mediated Signaling Pathway Regulation Of Hematopoietic Stem Cell Differentiation Oocyte Growth Regulation Of Viral Genome Replication Negative Regulation Of Viral Process Cellular Response To Stress Cellular Macromolecular Complex Assembly Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Intestinal Epithelial Structure Maintenance Evasion Or Tolerance Of Host Defenses By Virus Regulation Of Metabolic Process Regulation Of MRNA Processing Regulation Of Transcription Factor Import Into Nucleus Regulation Of Translational Initiation By EIF2 Alpha Phosphorylation
Tagcloud ?			acting analogues axis cll cytotoxicity dca dichloroacetate emphasize exhibits harboring hl indeed invariably knocking leukemic lymphocytic maver mec mediating merits options p21 p53mutated p53null p53wild proteomic purine sirnas underscored
Tagcloud (Difference) ?			acting analogues axis cll cytotoxicity dca dichloroacetate emphasize exhibits harboring hl indeed invariably knocking leukemic lymphocytic maver mec mediating merits options p21 p53mutated p53null p53wild proteomic purine sirnas underscored
Tagcloud (Intersection) ?